Search Results - "Whatley, R.E."
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Synthesis of platelet-activating factor by endothelial cells. The role of G proteins
Published in The Journal of biological chemistry (15-09-1990)“…Production of the potent lipid autacoid, platelet-activating factor (PAF), is a stimulated response of the endothelium which has important physiologic…”
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Activation of the acetyl-coenzyme A:lysoplatelet-activating factor acetyltransferase regulates platelet-activating factor synthesis in human endothelial cells
Published in The Journal of biological chemistry (15-11-1992)“…Platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine; PAF) is a phospholipid with many physiological actions. It is synthesized by…”
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P-selectin is acylated with palmitic acid and stearic acid at cysteine 766 through a thioester linkage
Published in The Journal of biological chemistry (25-05-1993)“…We report that the adhesion receptor P-selectin can be metabolically labeled with [3H]palmitic acid in human platelets. Analysis of alkaline methanolysis…”
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Growth-dependent changes in arachidonic acid release from endothelial cells are mediated by protein kinase C and changes in diacylglycerol
Published in The Journal of biological chemistry (05-08-1993)“…When stimulated, endothelial cells release arachidonic acid from phospholipids and oxidize it to eicosanoids. The rate-limiting step in this pathway is the…”
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Relative amounts of 1-O-alkyl- and 1-acyl-2-acetyl-sn-glycero-3-phosphocholine in stimulated endothelial cells
Published in Prostaglandins (01-01-1992)“…The specific precursor for platelet-activating factor, 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine, constitutes 10 per cent of the…”
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