Search Results - "Whatley, Angela S"
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High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase
Published in Nucleic acids research (01-02-2013)“…Systematic evolution of ligands through exponential enrichment (SELEX) is a well-established method for generating nucleic acid populations that are enriched…”
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Potent Inhibition of HIV-1 Reverse Transcriptase and Replication by Nonpseudoknot, “UCAA-motif” RNA Aptamers
Published in Molecular therapy. Nucleic acids (01-02-2013)“…RNA aptamers that bind the reverse transcriptase (RT) of human immunodeficiency virus (HIV) compete with nucleic acid primer/template for access to RT, inhibit…”
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Biochemical, inhibition and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase
Published in Nucleic acids research (01-01-2012)“…We report key mechanistic differences between the reverse transcriptases (RT) of human immunodeficiency virus type-1 (HIV-1) and of xenotropic murine leukemia…”
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Behavioral Health Information Technology: From Chaos To Clarity
Published in Health Affairs (01-06-2016)“…The use of health information technology (IT) in general health care has been shown to have significant potential to facilitate the delivery of safe,…”
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Robust Suppression of HIV Replication by Intracellularly Expressed Reverse Transcriptase Aptamers Is Independent of Ribozyme Processing
Published in Molecular therapy (01-12-2012)“…RNA aptamers that bind human immunodeficiency virus 1 (HIV-1) reverse transcriptase (RT) also inhibit viral replication, making them attractive as therapeutic…”
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