Search Results - "Whalen, Meghan"

The Impact of Extended Treatment With Artemether-lumefantrine on Antimalarial Exposure and Reinfection Risks in Ugandan Children With Uncomplicated Malaria: A Randomized Controlled Trial by Whalen, Meghan E, Kajubi, Richard, Goodwin, Justin, Orukan, Francis, Colt, McKenzie, Huang, Liusheng, Richards, Kacey, Wang, Kaicheng, Li, Fangyong, Mwebaza, Norah, Aweeka, Francesca T, Parikh, Sunil

“…Artemether-lumefantrine (AL) is the most widely used artemisinin-based combination therapy in Sub-Saharan Africa and is threatened by the emergence of…”
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Persistent and multiclonal malaria parasite dynamics despite extended artemether-lumefantrine treatment in children by Goodwin, Justin, Kajubi, Richard, Wang, Kaicheng, Li, Fangyong, Wade, Martina, Orukan, Francis, Huang, Liusheng, Whalen, Meghan, Aweeka, Francesca T., Mwebaza, Norah, Parikh, Sunil

“…Standard diagnostics used in longitudinal antimalarial studies are unable to characterize the complexity of submicroscopic parasite dynamics, particularly in…”
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Reduced Exposure to Piperaquine, Compared to Adults, in Young Children Receiving Dihydroartemisinin‐Piperaquine as Malaria Chemoprevention by Whalen, Meghan E., Kajubi, Richard, Chamankhah, Nona, Huang, Liusheng, Orukan, Francis, Wallender, Erika, Kamya, Moses R., Dorsey, Grant, Jagannathan, Prasanna, Rosenthal, Philip J., Mwebaza, Norah, Aweeka, Francesca T.

“…Dihydroartemisinin (DHA)‐piperaquine is being evaluated as intermittent preventive therapy for malaria, but dosing has not been optimized for children. We…”
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Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children by Wallender, Erika, Ali, Ali Mohamed, Hughes, Emma, Kakuru, Abel, Jagannathan, Prasanna, Muhindo, Mary Kakuru, Opira, Bishop, Whalen, Meghan, Huang, Liusheng, Duvalsaint, Marvin, Legac, Jenny, Kamya, Moses R., Dorsey, Grant, Aweeka, Francesca, Rosenthal, Philip J., Savic, Rada M.

“…Intermittent preventive treatment (IPT) with dihydroartemisinin-piperaquine (DP) is highly protective against malaria in children, but is not standard in…”
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Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092 by Owor, Maxensia, Tierney, Camlin, Ziemba, Lauren, Browning, Renee, Moye, John, Graham, Bobbie, Reding, Christina, Costello, Diane, Norman, Jennifer, Wiesner, Lubbe, Hughes, Emma, Whalen, Meghan E., Purdue, Lynette, Mmbaga, Blandina Theophil, Kamthunzi, Portia, Kawalazira, Rachel, Nathoo, Kusum, Bradford, Sarah, Coletti, Anne, Aweeka, Francesca, Musoke, Philippa

“…Severe acute malnutrition (SAM) may alter the pharmacokinetics (PK), efficacy, and safety of antiretroviral therapy. The phase IV study, IMPAACT P1092,…”
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Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance–Mediating Polymorphisms in Uganda by Conrad, Melissa D., Mota, Daniel, Foster, Marissa, Tukwasibwe, Stephen, Legac, Jennifer, Tumwebaze, Patrick, Whalen, Meghan, Kakuru, Abel, Nayebare, Patience, Wallender, Erika, Havlir, Diane V., Jagannathan, Prasanna, Huang, Liusheng, Aweeka, Francesca, Kamya, Moses R., Dorsey, Grant, Rosenthal, Philip J.

“…In a recent trial of intermittent preventive treatment in pregnancy (IPTp) in Uganda, dihydroartemisinin-piperaquine (DP) was superior to…”
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Determination of unbound piperaquine in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry by Huang, Liusheng, Sok, Vong, Aslam-Mir, Usman, Marzan, Florence, Whalen, Meghan, Rosenthal, Philip J., Aweeka, Francesca

“…•Paradoxical matrix effects for PQ and PQ-d6 observed in ESI+ diminished in APCI+.•Interference found in clinical sample analysis leads to UHPLC method…”
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Sodalis ligni Strain 159R Isolated from an Anaerobic Lignin-Degrading Consortium by Chaput, Gina, Ford, Jacob, DeDiego, Lani, Narayanan, Achala, Tam, Wing Yin, Whalen, Meghan, Huntemann, Marcel, Clum, Alicia, Spunde, Alex, Pillay, Manoj, Palaniappan, Krishnaveni, Varghese, Neha, Mikhailova, Natalia, Chen, I-Min, Stamatis, Dimitrios, Reddy, T B K, O'Malley, Ronan, Daum, Chris, Shapiro, Nicole, Ivanova, Natalia, Kyrpides, Nikos C, Woyke, Tanja, Glavina Del Rio, Tijana, DeAngelis, Kristen M

“…Novel bacterial isolates with the capabilities of lignin depolymerization, catabolism, or both, could be pertinent to lignocellulosic biofuel applications. In…”
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Combined Enzyme- and Transition Metal-Catalyzed Strategy for the Enantioselective Syntheses of Nitrogen Heterocycles: (−)-Coniine, DAB-1, and Nectrisine by Deardorff, Donald R, Niman, Scott W, Paulsen, Mark I, Sookezian, Anasheh, Whalen, Meghan E, Finlayson, Christopher J, Frivold, Collrane, Brown, Hilary C, Cannon, Jeffrey S

“…The enantioselective syntheses of (−)-coniine, DAB-1, and nectrisine have been developed, utilizing a complementary strategy of enzyme- and transition…”
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Optimization of Malaria Treatment Strategies: A Pharmacokinetic and Pharmacodynamic Analysis of Artemether-Lumefantrine in the Context of Pediatrics and HIV by Whalen, Meghan

“…Malaria remains a leading cause of morbidity and mortality worldwide, with young children at particular risk for severe, or complicated disease. The…”
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Comparative effectiveness of aerosolized versus oral ribavirin for the treatment of respiratory syncytial virus infections: A single‐center retrospective cohort study and review of the literature by Trang, Tracy P., Whalen, Meghan, Hilts‐Horeczko, Alexandra, Doernberg, Sarah B., Liu, Catherine

“…Background Respiratory syncytial virus (RSV) is a leading cause of viral infections in immunocompromised hosts and is associated with significant morbidity and…”
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Pharmacokinetics and Safety of Zidovudine, Lamivudine, and Lopinavir/Ritonavir in HIV-infected Children With Severe Acute Malnutrition in Sub-Saharan Africa: IMPAACT Protocol P1092 by Owor, Maxensia, Tierney, Camlin, Ziemba, Lauren, Browning, Renee, Moye, John, Graham, Bobbie, Reding, Christina, Costello, Diane, Norman, Jennifer, Wiesner, Lubbe, Hughes, Emma, Whalen, Meghan E., Purdue, Lynette, Mmbaga, Blandina Theophil, Kamthunzi, Portia, Kawalazira, Rachel, Nathoo, Kusum, Bradford, Sarah, Coletti, Anne, Aweeka, Francesca, Musoke, Philippa

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Complete Genome Sequence of Serratia quinivorans Strain 124R, a Facultative Anaerobe Isolated on Organosolv Lignin as a Sole Carbon Source by Chaput, Gina, Ford, Jacob, DeDiego, Lani, Narayanan, Achala, Tam, Wing Yin, Whalen, Meghan, Huntemann, Marcel, Clum, Alicia, Spunde, Alex, Pillay, Manoj, Palaniappan, Krishnaveni, Varghese, Neha, Mikhailova, Natalia, Chen, I-Min, Stamatis, Dimitrios, Reddy, T B K, O'Malley, Ronan, Daum, Chris, Shapiro, Nicole, Ivanova, Natalia, Kyrpides, Nikos C, Woyke, Tanja, Glavina Del Rio, Tijana, DeAngelis, Kristen

“…The complete genome sequence of the gammaproteobacterial isolate 124R consists of 5 Mb over 2 scaffolds and a G+C content of 52.85%. Genes relating to aromatic…”
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