Search Results - "Weyden, L"

Widespread metastasis of a spermatocytic seminoma with concomitant hepatic peliosis in a Southern African hedgehog () by O'dell, N, O'dell, JH, van der Weyden, L

“…A six-year-old intact male Southern African hedgehog (Atelerix frontalis) presented with a history of chronic mild to moderate weight loss, and sub-acute hind…”
Get full text

The RASSF1A Isoform of RASSF1 Promotes Microtubule Stability and Suppresses Tumorigenesis by van der Weyden, L., Tachibana, K. K., Gonzalez, M. A., Adams, D. J., Ng, B. L., Petty, R., Venkitaraman, A. R., Arends, M. J., Bradley, A.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity by van der Weyden, L, Rust, A G, McIntyre, R E, Robles-Espinoza, C D, del Castillo Velasco-Herrera, M, Strogantsev, R, Ferguson-Smith, A C, McCarthy, S, Keane, T M, Arends, M J, Adams, D J

“…We performed a genetic screen in mice to identify candidate genes that are associated with leukaemogenesis in the context of Trp53 heterozygosity. To do this…”
Get full text

Loss of Rassf1a cooperates with Apc(Min) to accelerate intestinal tumourigenesis by van der Weyden, L, Arends, M J, Dovey, O M, Harrison, H L, Lefebvre, G, Conte, N, Gergely, F V, Bradley, A, Adams, D J

“…Promoter methylation of the RAS-association domain family 1, isoform A gene (RASSF1A) is one of the most frequent events found in human tumours. In this study…”
Get full text

Loss of Rassf1a cooperates with ApcMin to accelerate intestinal tumourigenesis by van der Weyden, L, Arends, M J, Dovey, O M, Harrison, H L, Lefebvre, G, Conte, N, Gergely, F V, Bradley, A, Adams, D J

“…Promoter methylation of the RAS-association domain family 1, isoform A gene ( RASSF1A ) is one of the most frequent events found in human tumours. In this…”
Get full text

Pharmacological characterisation of the P2Y11 receptor in stably transfected haematological cell lines by van der Weyden, L, Adams, D J, Luttrell, B M, Conigrave, A D, Morris, M B

“…The recently cloned P2Y11 receptor is unique amongst P2Y receptors with its coupling to the adenylyl cyclase pathway. P2Y11 has previously been shown to be…”
Get full text

cAMP controls human renin mRNA stability via specific RNA-binding proteins by Morris, B. J., Adams, D. J., Beveridge, D. J., van der Weyden, L., Mangs, H., Leedman, P. J.

“…It is now recognized that post‐transcriptional mechanisms are pivotal to renin production. These involve factors that modulate renin mRNA stability. In 2003…”
Get full text

Genetic determinants of micronucleus formation in vivo by Adams, D. J., Barlas, B., McIntyre, R. E., Salguero, I., van der Weyden, L., Barros, A., Vicente, J. R., Karimpour, N., Haider, A., Ranzani, M., Turner, G., Thompson, N. A., Harle, V., Olvera-León, R., Robles-Espinoza, C. D., Speak, A. O., Geisler, N., Weninger, W. J., Geyer, S. H., Hewinson, J., Karp, N. A., Fu, B., Yang, F., Kozik, Z., Choudhary, J., Yu, L., van Ruiten, M. S., Rowland, B. D., Lelliott, C. J., del Castillo Velasco-Herrera, M., Verstraten, R., Bruckner, L., Henssen, A. G., Rooimans, M. A., de Lange, J., Mohun, T. J., Arends, M. J., Kentistou, K. A., Coelho, P. A., Zhao, Y., Zecchini, H., Perry, J. R. B., Jackson, S. P., Balmus, G.

“…Genomic instability arising from defective responses to DNA damage 1 or mitotic chromosomal imbalances 2 can lead to the sequestration of DNA in aberrant…”
Get full text

Association of aberrant ASNS imprinting with asparaginase sensitivity and chromosomal abnormality in childhood BCP-ALL by Watanabe, Atsushi, Miyake, Kunio, Nordlund, Jessica, Syvänen, Ann-Christine, van der Weyden, Louise, Honda, Hiroaki, Yamasaki, Norimasa, Nagamachi, Akiko, Inaba, Toshiya, Ikawa, Tomokatsu, Urayama, Kevin Y., Kiyokawa, Nobutaka, Ohara, Akira, Kimura, Shunsuke, Kubota, Yasuo, Takita, Junko, Goto, Hiroaki, Sakaguchi, Kimiyoshi, Minegishi, Masayoshi, Iwamoto, Shotaro, Shinohara, Tamao, Kagami, Keiko, Abe, Masako, Akahane, Koshi, Goi, Kumiko, Sugita, Kanji, Inukai, Takeshi

“…Karyotype is an important prognostic factor in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL), but the underlying pharmacogenomics remain…”
Get full text

Signal transduction and white cell maturation via extracellular ATP and the P2Y receptor by Weyden, V L, Conigrave, A, Morris, M

“…Extracellular ATP promotes a wide range of physiological effects in many tissues. Of particular interest is the effect of ATP on leukaemia-derived HL-60 and…”
Get full text

Chromosome localization and characterization of the mouse and human zinc finger protein 265 gene by Adams, D J, van der Weyden, L, Kovacic, A, Lovicu, F J, Copeland, N G, Gilbert, D J, Jenkins, N A, Ioannou, P A, Morris, B J

“…The chromosome location and pattern of expression of the gene encoding the zinc finger protein 265 (alias "Zis") in human (ZNF265) and mouse (Zfp265) was…”
Get more information

Amino acid sequence of a neurotoxic phospholipase A2 enzyme from common death adder (Acanthophis antracticus) venom by van der Weyden, L, Hains, P, Broady, K, Shaw, D, Milburn, P

“…The amino acid sequence of the first neurotoxic phospholipase A2, acanthoxin A1, purified from the venom of the Common death adder (Acanthophis antarcticus)…”
Get more information

Functional Knockout of the Matrilin-3 Gene Causes Premature Chondrocyte Maturation to Hypertrophy and Increases Bone Mineral Density and Osteoarthritis by van der Weyden, Louise, Wei, Lei, Luo, Junming, Yang, Xu, Birk, David E., Adams, David J., Bradley, Allan, Chen, Qian

“…Mutations in the gene encoding matrilin-3 ( MATN3), a noncollagenous extracellular matrix protein, have been reported in a variety of skeletal diseases,…”
Get full text

Tools for targeted manipulation of the mouse genome by van der Weyden, Louise, Adams, David J, Bradley, Allan

“…The Wellcome Trust Sanger Institute, Hinxton, Cambs CB10 1SA, United Kingdom In the postgenomic era the mouse will be central to the challenge of ascribing a…”
Get full text

Mutagenic Insertion and Chromosome Engineering Resource (MICER) by Bradley, Allan, Adams, David J, Biggs, Patrick J, Cox, Tony, Davies, Rob, van der Weyden, Louise, Jonkers, Jos, Smith, James, Plumb, Bob, Taylor, Ruth, Nishijima, Ichiko, Yu, Yuejin, Rogers, Jane

“…Embryonic stem cell technology revolutionized biology by providing a means to assess mammalian gene function in vivo. Although it is now routine to generate…”
Get full text

A genome-wide, end-sequenced 129Sv BAC library resource for targeting vector construction by Adams, David J., Quail, Michael A., Cox, Tony, van der Weyden, Louise, Gorick, Barbara D., Su, Qin, Chan, Wei-in, Davies, Rob, Bonfield, James K., Law, Frances, Humphray, Sean, Plumb, Bob, Liu, Pentao, Rogers, Jane, Bradley, Allan

“…The majority of gene-targeting experiments in mice are performed in 129Sv-derived embryonic stem (ES) cell lines, which are generally considered to be more…”
Get full text

Extracellular ATP couples to cAMP generation and granulocytic differentiation in human NB4 promyelocytic leukaemia cells by van der Weyden, L, Rakyan, V, Luttrell, B M, Morris, M B, Conigrave, A D

“…Priming of NB4 promyelocytic cells with all-trans retinoic acid, followed by extracellular ATP in the presence of a phosphodiesterase inhibitor, elevated cAMP…”
Get full text

Loss of Rassf1a cooperates with [Apc.sup.Min] to accelerate intestinal tumourigenesis by van der Weyden, L, Arends, M.J, Dovey, O.M, Harrison, H.L, Lefebvre, G, Conte, N, Gergely, F.V, Bradley, A, Adams, D.J

Get full text

HADHB, HuR, and CP1 Bind to the Distal 3′-Untranslated Region of Human Renin mRNA and Differentially Modulate Renin Expression by Adams, David J., Beveridge, Dianne J., van der Weyden, Louise, Mangs, Helena, Leedman, Peter J., Morris, Brian J.

“…Production of renin is critically dependent on modulation of REN mRNA stability. Here we sought to elucidate the molecular mechanisms involved. Transfections…”
Get full text

Loss of Rassf1a cooperates with Apc Min to accelerate intestinal tumourigenesis by Van der Weyden, L, Arends, M J, Dovey, O M, Harrison, H L, Lefebvre, G, Conte, N, Gergely, F V, Bradley, A, Adams, D J

“…Promoter methylation of the RAS-association domain family 1, isoform A gene (RASSF1A) is one of the most frequent events found in human tumours. In this study…”
Get full text