Search Results - "Wey, Shiuan"

Role of the unfolded protein response regulator GRP78/BiP in development, cancer, and neurological disorders by Wang, Miao, Wey, Shiuan, Zhang, Yi, Ye, Risheng, Lee, Amy S

“…GRP78/BiP is a major endoplasmic reticulum (ER) chaperone protein critical for protein quality control of the ER, as well as controlling the activation of the…”
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Candid covariance-free incremental principal component analysis by Weng, Juyang, Zhang, Yilu, Hwang, Wey-Shiuan

“…Appearance-based image analysis techniques require fast computation of principal components of high-dimensional image vectors. We introduce a fast incremental…”
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Head and Neck Mesenchymal Neoplasms With GLI1 Gene Alterations: A Pathologic Entity With Distinct Histologic Features and Potential for Distant Metastasis by Xu, Bin, Chang, Koping, Folpe, Andrew L., Kao, Yu-Chien, Wey, Shiuan-Li, Huang, Hsuan-Ying, Gill, Anthony J., Rooper, Lisa, Bishop, Justin A., Dickson, Brendan C., Lee, Jen-Chieh, Antonescu, Cristina R.

“…Soft tissue tumors with GLI1 gene fusions or amplifications have been recently described as a unique pathologic entity with an established risk of malignancy…”
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Monoclonal Antibody against Cell Surface GRP78 as a Novel Agent in Suppressing PI3K/AKT Signaling, Tumor Growth, and Metastasis by REN LIU, XIUQING LI, GENYUAN ZHU, LOUIE, Stan, CONTI, Peter S, ZIBO LI, LEE, Amy S, GILL, Parkash S, WENMING GAO, YUE ZHOU, SHIUAN WEY, MITRA, Satyajit K, KRASNOPEROV, Valery, DEZHENG DONG, SHUANGLONG LIU, DAN LI

“…The ER chaperone GRP78 translocates to the surface of tumor cells and promotes survival, metastasis, and resistance to therapy. An oncogenic function of cell…”
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Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium by Fu, Yong, Wey, Shiuan, Wang, Miao, Ye, Risheng, Liao, Chun-Peng, Roy-Burman, Pradip, Lee, Amy S

“…GRP78/BiP has recently emerged as a novel biomarker for aggressive prostate cancer. Here, we report that homozygous deletion of Grp78 specifically in mouse…”
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Incremental Hierarchical Discriminant Regression by Weng, Juyang, Hwang, Wey-Shiuan

“…This paper presents incremental hierarchical discriminant regression (IHDR) which incrementally builds a decision tree or regression tree for very…”
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Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP by Ni, Min, Zhou, Hui, Wey, Shiuan, Baumeister, Peter, Lee, Amy S

“…The unfolded protein response (UPR) is an evolutionarily conserved mechanism to allow cells to adapt to stress targeting the endoplasmic reticulum (ER)…”
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Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling by Wey, Shiuan, Luo, Biquan, Lee, Amy S

“…GRP78, a master regulator of the unfolded protein response (UPR) and cell signaling, is required for inner cell mass survival during early embryonic…”
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Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling by Wey, Shiuan, Luo, Biquan, Tseng, Chun-Chih, Ni, Min, Zhou, Hui, Fu, Yong, Bhojwani, Deepa, Carroll, William L., Lee, Amy S.

“…Traditionally, GRP78 is regarded as protective against hypoxia and nutrient starvation prevalent in the microenvironment of solid tumors; thus, its role in the…”
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Antifibrotic Effect of Bletilla striata Polysaccharide-Resveratrol-Impregnated Dual-Layer Carboxymethyl Cellulose-Based Sponge for The Prevention of Epidural Fibrosis after Laminectomy by Chen, Hsuan-Yu, Lin, Tzu-Chieh, Chiang, Chih-Yung, Wey, Shiuan-Li, Lin, Feng-Huei, Yang, Kai-Chiang, Chang, Chih-Hao, Hu, Ming-Hsiao

“…The application of antifibrotic materials can alleviate epidural fibrosis by restricting excessive fibroblast proliferation and mitigating scar tissue…”
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Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling by Mao, Changhui, Wang, Miao, Luo, Biquan, Wey, Shiuan, Dong, Dezheng, Wesselschmidt, Robin, Rawlings, Stephen, Lee, Amy S

“…Glucose-regulated protein 94 (GRP94) is one of the most abundant endoplasmic reticulum (ER) resident proteins and is the ER counterpart of the cytoplasmic heat…”
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Intestinal Bleeding Caused by Combined Cytomegalovirus Enteritis and Adverse Effect of Kalimate in Elderly: A Case Report by Shiuan-Li Wey, Jie-Ying Wu

“…Gastrointestinal (GI) bleeding is one of the major indications for hospitalization in the elderly. The most common causes of GI bleeding in elders include…”
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Three dimensional rendering of the mitochondrial sheath morphogenesis during mouse spermiogenesis by Ho, Han-Chen, Wey, Shiuan

“…In the middle piece of mouse sperm tail, the idea of the mitochondria wrapping in a sinistral (left‐handed) double helical structure was generally accepted. In…”
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Novel Application of Photo-Crosslinked Urocanic-Acid-Modified Chitosan in Corneal Wounds by Lee, An-Li, Hsieh, Hao-Ying, Chen, Yun-Yu, Tsai, Li-Hui, Wey, Shiuan-Li, Chen, Dai-Shi, Chen, Yi-Jane, Young, Tai-Horng

“…In the last few years, the use of tissue adhesives in corneal perforation has gained immense popularity in clinical practices. The present study aimed to…”
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The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche by Luo, Biquan, Lam, Ben S, Lee, Sung Hyung, Wey, Shiuan, Zhou, Hui, Wang, Miao, Chen, Si-Yi, Adams, Gregor B, Lee, Amy S

“…Hematopoietic stem cell (HSC) homeostasis in the adult bone marrow (BM) is regulated by both intrinsic gene expression products and interactions with extrinsic…”
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Desmoplastic Medulloblastoma Arising From an Ovarian Teratoma: A Case Report and Review of the Literature by Wey, Shiuan-Li, Chen, Chi-Kuan, Chen, Tze-Chien, Chen, Tung-Ying

“…The primary neuroectodermal tumor of the ovary is extremely rare, and it manifests in 3 forms: differentiated, primitive, and anaplastic. The medulloblastoma…”
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Tumor-to-Tumor Metastasis: Lung Carcinoma Metastasizing to Thyroid Neoplasms by Wey, Shiuan-Li, Chang, Kuo-Ming

“…Tumor-to-tumor metastasis is extremely rare in the thyroid glands, and only seven cases of lung carcinoma metastasizing to thyroid tumors have been reported in…”
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Poorly differentiated thyroid carcinoma in a 9-year-old boy: case report by Wu, Yi-Lei, Ting, Wei-Hsin, Wey, Shiuan-Li, Chen, Chi-Kuan, Huang, Chi-Yu, Cheng, Shih-Ping, Lees, Yann-Jinn

“…Poorly differentiated thyroid carcinoma (PDTC) is a rare disease with a poor prognosis in children. We describe a 9-year-old boy with a thyroid nodule composed…”
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Auditory learning: a developmental method by Zhang, Yilu, Weng, Juyang, Hwang, Wey-Shiuan

“…Motivated by the human autonomous development process from infancy to adulthood, we have built a robot that develops its cognitive and behavioral skills…”
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Antifungal Resistance and Predictors of Response in Patients with Hematologic Malignancy by Wey, Shiuan (Shannon), Kriengkauykiat, Jane, Chan, Ayla, Tegtmeier, Bernard, Ito, James, Dadwal, Sanjeet

“…Abstract Background Invasive aspergillosis (IA) causes significant morbidity and mortality in patients with hematologic malignancies (HM). Azole resistance has…”
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