Search Results - "Wewetzer, Konstantin"
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Intranasal Borna Disease Virus (BoDV-1) Infection: Insights into Initial Steps and Potential Contagiosity
Published in International journal of molecular sciences (15-03-2019)“…Mammalian Bornavirus (BoDV-1) typically causes a fatal neurologic disorder in horses and sheep, and was recently shown to cause fatal encephalitis in humans…”
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Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation
Published in PloS one (21-07-2015)“…Gliogenesis under pathophysiological conditions is of particular clinical relevance since it may provide evidence for regeneration promoting cells recruitable…”
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Prominent Microglial Activation in the Early Proinflammatory Immune Response in Naturally Occurring Canine Spinal Cord Injury
Published in Journal of neuropathology and experimental neurology (01-08-2011)“…Better understanding of the pathogenesis of spinal cord injury (SCI) is needed for the development of new therapeutic strategies. Spinal cord injury has been…”
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Transcriptional changes in canine distemper virus-induced demyelinating leukoencephalitis favor a biphasic mode of demyelination
Published in PloS one (01-04-2014)“…Canine distemper virus (CDV)-induced demyelinating leukoencephalitis in dogs (Canis familiaris) is suggested to represent a naturally occurring translational…”
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Toward defining the regenerative potential of olfactory mucosa: establishment of Schwann cell-free adult canine olfactory ensheathing cell preparations suitable for transplantation
Published in Cell transplantation (01-01-2013)“…Olfactory mucosa (OM)-derived olfactory ensheathing cells (OECs) are attractive candidates for autologous cell transplantation-based therapy of nervous system…”
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Transcriptional profiling predicts overwhelming homology of schwann cells, olfactory ensheathing cells, and schwann cell-like glia
Published in Glia (01-10-2014)“…Schwann cells (SCs), olfactory ensheathing cells (OECs), and central nervous system Schwann cell‐like glia (SG) represent a group of nerve growth factor…”
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Schwann cell-free adult canine olfactory ensheathing cell preparations from olfactory bulb and mucosa display differential migratory and neurite growth-promoting properties in vitro
Published in BMC neuroscience (13-11-2013)“…Transplantation of olfactory ensheathing cells (OEC) and Schwann cells (SC) is a promising therapeutic strategy to promote axonal growth and remyelination…”
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Transplantation of olfactory ensheathing cells as adjunct cell therapy for peripheral nerve injury
Published in Cell transplantation (01-03-2011)“…Traumatic events, such as work place trauma or motor vehicle accident violence, result in a significant number of severe peripheral nerve lesions, including…”
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Vimentin-positive astrocytes in canine distemper: a target for canine distemper virus especially in chronic demyelinating lesions?
Published in Acta neuropathologica (01-12-2007)“…In canine distemper demyelinating leukoencephalitis (DL), caused by canine distemper virus (CDV), astrocytes represent the main virus target. In these cells,…”
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Olfactory ensheathing glia and Schwann cells: two of a kind?
Published in Cell and tissue research (01-09-2002)“…Both olfactory ensheathing cells (OECs) and Schwann cells have been shown to promote axonal regrowth and remyelination in the central (CNS) and peripheral…”
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Phagocytosis of O4+ axonal fragments in vitro by p75− neonatal rat olfactory ensheathing cells
Published in Glia (01-03-2005)“…Olfactory ensheathing cells (OECs) have gained wide interest because of their unique regeneration‐promoting capacity. However, despite their frequent use in…”
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Highly malignant behavior of a murine oligodendrocyte precursor cell line following transplantation into the demyelinated and nondemyelinated central nervous system
Published in Cell transplantation (01-01-2012)“…Understanding the basic mechanisms that control CNS remyelination is of direct clinical relevance. Suitable model systems include the analysis of naturally…”
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Remyelination of the nonhuman primate spinal cord by transplantation of H‐transferase transgenic adult pig olfactory ensheathing cells
Published in The FASEB journal (01-02-2004)“…Olfactory ensheathing cells (OECs) have been shown to mediate remyelination and to stimulate axonal regeneration in a number of in vivo rodent spinal cord…”
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Expression of interleukin-6 and its receptor in the sciatic nerve and cultured Schwann cells: relation to 18-kD fibroblast growth factor-2
Published in Brain research (08-12-2000)“…Expression of interleukin-6 (IL-6) and fibroblast growth factor-2 (FGF-2) in Schwann cells is modulated by external stimuli. To study possible interactions of…”
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Cell-cell interaction appears to represent a pivotal factor for susceptibility of adult canine Schwann cell-like brain glia to canine distemper virus infection in vitro
Published in Wētchasān sattawaphāet (01-06-2011)“…Recently, we reported the preferential infection of a novel glial cell type from adult canine brain, termed Schwann cell-like brain glia (SCBG) with canine…”
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Translating basic research into clinical practice or what else do we have to learn about olfactory ensheathing cells?
Published in Neuroscience letters (12-06-2009)“…Olfactory ensheathing cells (OECs) are Schwann cell-like glial cells of the olfactory system that have been shown to promote axonal regeneration and…”
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Species-specific control of cellular proliferation and the impact of large animal models for the use of olfactory ensheathing cells and Schwann cells in spinal cord repair
Published in Experimental neurology (01-05-2011)“…Autologous transplantation of olfactory ensheathing cells (OECs) and Schwann cells (SCs) is considered a promising option to promote axonal regrowth and…”
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Regeneration of a transected peripheral nerve by transplantation of spinal cord encapsulated in a vein
Published in Neuroreport (08-05-2001)“…The objective was to investigate the regeneration of a transected peripheral nerve after transplantation of fragmented embryonic (E14–15) spinal cord cells…”
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Immunocytochemical localization of the heparin-binding growth-associated molecule (HB-GAM) in the developing and adult rat cerebellar cortex
Published in Brain research (25-09-1995)“…The heparin-binding, growth-associated molecule (HB-GAM) is a developmentally regulated protein that belongs to a new family of heparin-binding molecules, not…”
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