Search Results - "Wever, Kimberley"
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Ischemic preconditioning in the animal kidney, a systematic review and meta-analysis
Published in PloS one (28-02-2012)“…Ischemic preconditioning (IPC) is a potent renoprotective strategy which has not yet been translated successfully into clinical practice, in spite of promising…”
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Humans are animals, but are animals human enough? A systematic review and meta-analysis on interspecies differences in renal drug clearance
Published in Drug discovery today (01-04-2020)“…•Allometric scaling is suitable for prediction of human renal drug clearance (CLr).•The average CLr of a diverse set of 20 drugs scales to the ¾ power of body…”
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Allopurinol to reduce cardiovascular morbidity and mortality: A systematic review and meta-analysis
Published in PloS one (02-12-2021)“…To compare the effectiveness of allopurinol with no treatment or placebo for the prevention of cardiovascular events in hyperuricemic patients. Pubmed, Web of…”
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A systematic review and meta-analysis of the protective effects of metformin in experimental myocardial infarction
Published in PloS one (23-08-2017)“…Metformin improves cardiovascular prognosis in patients with diabetes mellitus, compared to alternative glucose-lowering drugs, despite similar glycemic…”
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5
Standardized mean differences cause funnel plot distortion in publication bias assessments
Published in eLife (08-09-2017)“…Meta-analyses are increasingly used for synthesis of evidence from biomedical research, and often include an assessment of publication bias based on visual or…”
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Pharmacological modulation of conditioned fear in the fear-potentiated startle test: a systematic review and meta-analysis of animal studies
Published in Psychopharmacology (01-11-2023)“…Rationale and objectives Fear conditioning is an important aspect in the pathophysiology of anxiety disorders. The fear-potentiated startle test is based on…”
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Determinants of the Efficacy of Cardiac Ischemic Preconditioning: A Systematic Review and Meta-Analysis of Animal Studies
Published in PloS one (18-11-2015)“…Ischemic preconditioning (IPC) of the heart is a protective strategy in which a brief ischemic stimulus immediately before a lethal ischemic episode potently…”
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Epidemiology and reporting characteristics of preclinical systematic reviews
Published in PLoS biology (05-05-2021)“…In an effort to better utilize published evidence obtained from animal experiments, systematic reviews of preclinical studies are increasingly more…”
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Renal Perfusion and Function during Pneumoperitoneum: A Systematic Review and Meta-Analysis of Animal Studies
Published in PloS one (22-09-2016)“…Both preclinical and clinical studies indicate that raised intra-abdominal pressure (IAP) associated with pneumoperitoneum during laparoscopic surgical…”
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A Systematic Review on Transplantation Studies of the Retinal Pigment Epithelium in Animal Models
Published in International journal of molecular sciences (01-04-2020)“…The retinal pigment epithelium (RPE) and the adjacent light-sensitive photoreceptors form a single functional unit lining the back of the eye. Both cell layers…”
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A 3-year evaluation of preclinicaltrials.eu reveals room for improvement in preregistration of animal studies
Published in PLoS biology (09-09-2021)“…In 2018, the first registry dedicated to preregistration of animal study protocols was launched. Despite international support, the overall number of…”
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The EQIPD framework for rigor in the design, conduct, analysis and documentation of animal experiments
Published in Nature methods (01-11-2022)“…The EQIPD framework for rigor in animal experiments aims to unify current recommendations based on evidence behind their rationale and was prospectively tested…”
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Teratoma Assay for Testing Pluripotency and Malignancy of Stem Cells: Insufficient Reporting and Uptake of Animal-Free Methods-A Systematic Review
Published in International journal of molecular sciences (15-02-2023)“…Pluripotency describes the ability of stem cells to differentiate into derivatives of the three germ layers. In reporting new human pluripotent stem cell…”
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Facilitating healthcare decisions by assessing the certainty in the evidence from preclinical animal studies
Published in PloS one (11-01-2018)“…Laboratory animal studies are used in a wide range of human health related research areas, such as basic biomedical research, drug research, experimental…”
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Reduced uterine perfusion pressure as a model for preeclampsia and fetal growth restriction in murine: a systematic review and meta-analysis
Published in American journal of physiology. Heart and circulatory physiology (01-07-2024)“…The reduced uterine perfusion pressure (RUPP) model is frequently used to study preeclampsia and fetal growth restriction. An improved understanding of…”
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Understanding changes in echocardiographic parameters at different ages following fetal growth restriction: a systematic review and meta-analysis
Published in American journal of physiology. Heart and circulatory physiology (01-06-2024)“…Fetal growth restriction (FGR) increases cardiovascular risk by cardiac remodeling and programming. This systematic review and meta-analysis across species…”
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Effects of postnatal corticosteroids on lung development in newborn animals. A systematic review
Published in Pediatric research (16-03-2024)“…Background Postnatal systemic corticosteroids reduce the risk of bronchopulmonary dysplasia but the effect depends on timing, dosing, and type of…”
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The transverse aortic constriction heart failure animal model: a systematic review and meta-analysis
Published in Heart failure reviews (01-11-2021)“…The transverse aortic constriction (TAC) model is frequently used to study adverse cardiac remodeling upon pressure overload. We set out to define the most…”
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Preclinical Evidence for the Efficacy of Ischemic Postconditioning against Renal Ischemia-Reperfusion Injury, a Systematic Review and Meta-Analysis
Published in PloS one (10-03-2016)“…Renal ischemia-reperfusion injury (IRI) is a major cause of kidney damage after e.g. renal surgery and transplantation. Ischemic postconditioning (IPoC) is a…”
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Navigating PROSPERO4animals: 10 top tips for efficient pre-registration of your animal systematic review protocol
Published in BMC medical research methodology (24-01-2024)“…Systematic reviews are an essential tool in identifying knowledge gaps and synthesizing evidence from in vivo animal research to improve human health. The…”
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