Search Results - "Wever, Claudia M"

Stoichiometry of the human glycine receptor revealed by direct subunit counting by Durisic, Nela, Godin, Antoine G, Wever, Claudia M, Heyes, Colin D, Lakadamyali, Melike, Dent, Joseph A

“…The subunit stoichiometry of heteromeric glycine-gated channels determines fundamental properties of these key inhibitory neurotransmitter receptors; however,…”
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The Validation of Nematode-Specific Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug Targets by Wever, Claudia M, Farrington, Danielle, Dent, Joseph A

“…New compounds are needed to treat parasitic nematode infections in humans, livestock and plants. Small molecule anthelmintics are the primary means of nematode…”
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Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors by Duguet, Thomas B, Charvet, Claude L, Forrester, Sean G, Wever, Claudia M, Dent, Joseph A, Neveu, Cedric, Beech, Robin N

“…Helminth parasites rely on fast-synaptic transmission in their neuromusculature to experience the outside world and respond to it. Acetylcholine plays a…”
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A 10-color flow cytometry panel for diagnosis and minimal residual disease in chronic lymphocytic leukemia by Bazinet, Alexandre, Rys, Ryan N., Barry, Amadou, Greenwood, Celia M. T., Young, Yoon Kow, Mendoza, Alma, LaPorta, Ida, Wever, Claudia M., Mercier, François E., Johnson, Nathalie A.

“…Diagnosis and minimal residual disease (MRD) monitoring of chronic lymphocytic leukemia (CLL) by flow cytometry currently requires multiple antibody panels. We…”
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Apoptotic Blocks in Primary Non-Hodgkin B Cell Lymphomas Identified by BH3 Profiling by Rys, Ryan N, Wever, Claudia M, Geoffrion, Dominique, Goncalves, Christophe, Ghassemian, Artin, Brailovski, Eugene, Ryan, Jeremy, Stoica, Liliana, Hébert, Josée, Petrogiannis-Haliotis, Tina, Dmitrienko, Svetlana, Frenkiel, Saul, Staiger, Annette, Ott, German, Steidl, Christian, Scott, David W, Sesques, Pierre, Del Rincon, Sonia, Mann, Koren K, Letai, Anthony, Johnson, Nathalie A

“…To determine causes of apoptotic resistance, we analyzed 124 primary B cell NHL samples using BH3 profiling, a technique that measures the mitochondrial…”
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The genomic landscape of two Burkitt lymphoma cases and derived cell lines: comparison between primary and relapse samples by Wever, Claudia M., Geoffrion, Dominique, Grande, Bruno M., Yu, Stephen, Alcaide, Miguel, Lemaire, Maryse, Riazalhosseini, Yasser, Hébert, Josée, Gavino, Christina, Vinh, Donald C., Petrogiannis-Haliotis, Tina, Dmitrienko, Svetlana, Mann, Koren K., Morin, Ryan D., Johnson, Nathalie A.

“…Relapse occurs in 10-40% of Burkitt lymphoma (BL) patients that have completed intensive chemotherapy regimens and is typically fatal. While treatment-naive BL…”
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A 10-Color Flow Cytometry Panel for Both Diagnosis and Minimal Residual Disease Measurement in Chronic Lymphocytic Leukemia by Bazinet, Alexandre, Rys, Ryan N, Wever, Claudia M, Barry, Amadou, Greenwood, Celia, Young, Christian, Mendoza, Alma, LaPorta, Ida, Gimmig, Sylvain, Mercier, François, Johnson, Nathalie

“…Background: Chronic lymphocytic leukemia (CLL) has a classic immunophenotype, consisting of light chain restriction, CD5+, CD19+, dim CD20, CD23+, CD43+,…”
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Understanding Apoptotic Blocks in “Double Hit” and Other Non-Hodgkin Lymphomas By BH3 Profiling by Wever, Claudia M, Geoffrion, Dominique, Sesques, Pierre, Stoica, Liliana, Hebert, Josee, Ryan, Jeremy, Letai, Anthony, Johnson, Nathalie A

“…Background: The anti-apoptotic protein BCL2 is expressed in chronic lymphocytic leukemias (CLL), 85% of follicular lymphomas (FL) and 60% of diffuse large B…”
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Abstract 2447: The mutational landscape of chemo-refractory Burkitt lymphoma by Wever, Claudia M., Lemaire, Maryse, Vinh, Donald C., Hébert, Josée, Riazalhosseini, Yasser, Morin, Ryan, Johnson, Nathalie A.

“…Abstract Background: Burkitt Lymphoma (BL) is characterized by rapid cellular proliferation driven by the canonical IG-MYC translocation. BL can evade…”
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Apoptotic Blocks in Primary Non-Hodgkin B-Cell Lymphomas Identified By BH3 Profiling by Johnson, Nathalie A, Wever, Claudia M, Geoffrion, Dominique, Artin, Ghassemian, Eugene, Brailovski, Sesques, Pierre, Ryan, Jeremy A., Stoica, Liliana, Hebert, Josee, Petrogiannis-Haliotis, Tina, Dmitrienko, Svetlana, Saul, Frenkiel, Ott, German, Staiger, Annette, Steidl, Christian, Scott, David W., Mann, Koren Kathleen, Letai, Anthony

“…Background: The anti-apoptotic protein BCL2 is expressed in most non-Hodgkin lymphomas (NHL) including chronic lymphocytic leukemias (CLL), mantle cell…”
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The Validation of Nematode-Specific Acetylcholine-Gated Chloride Channels as Potential Anthelmintic Drug Targets: e0138804 by Wever, Claudia M, Farrington, Danielle, Dent, Joseph A

“…New compounds are needed to treat parasitic nematode infections in humans, livestock and plants. Small molecule anthelmintics are the primary means of nematode…”
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