Search Results - "Wetzel, J D"

Cells and viruses with mutations affecting viral entry are selected during persistent infections of L cells with mammalian reoviruses by DERMODY, T. S, NIBERT, M. L, WETZEL, J. D, XIAO TONG, FIELDS, B. N

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Efficiency of viral entry determines the capacity of murine erythroleukemia cells to support persistent infections by mammalian reoviruses by Wetzel, J D, Chappell, J D, Fogo, A B, Dermody, T S

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Reovirus variants selected during persistent infections of L cells contain mutations in the viral S1 and S4 genes and are altered in viral disassembly by Wetzel, J D, Wilson, G J, Baer, G S, Dunnigan, L R, Wright, J P, Tang, D S, Dermody, T S

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Isolation and Molecular Characterization of a Novel Type 3 Reovirus from a Child with Meningitis by Tyler, Kenneth L., Barton, Erik S., Ibach, Maria L., Robinson, Christine, Campbell, Jacquelyn A., O'Donnell, Sean M., Valyi-Nagy, Tibor, Clarke, Penny, Wetzel, J. Denise, Dermody, Terence S.

“…Mammalian reoviruses are nonenveloped viruses that contain a segmented, double-stranded RNA genome. Reoviruses infect most mammalian species, although…”
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Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease by Barton, E S, Youree, B E, Ebert, D H, rest, J C, Connolly, J L, Valyi-Nagy, T, Washington, K, Wetzel, J D, Dermody, T S

“…Infection of neonatal mice with some reovirus strains produces a disease similar to infantile biliary atresia, but previous attempts to correlate reovirus…”
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Detection of Mammalian Reovirus RNA by Using Reverse Transcription-PCR: Sequence Diversity within the lambda 3-Encoding L1 Gene by Leary, T P, Erker, J C, Chalmers, M L, Cruz, A T, Wetzel, J D, Desai, S M, Mushahwar, I K, Dermody, T S

“…Reoviruses infect virtually all mammalian species, and infection of humans is associated with mild gastrointestinal or upper respiratory illnesses. To improve…”
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Mutations in type 3 reovirus that determine binding to sialic acid are contained in the fibrous tail domain of viral attachment protein sigma 1 by Chappell, J D, Gunn, V L, Wetzel, J D, Baer, G S, Dermody, T S

“…The reovirus attachment protein, sigma 1, determines numerous aspects of reovirus-induced disease, including viral virulence, pathways of spread, and tropism…”
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A Monoclonal Antibody Specific for Reovirus Outer-Capsid Protein sigma 3 Inhibits sigma 1-Mediated Hemagglutination by Steric Hindrance by Nason, EL, Wetzel, J D, Mukherjee, S K, Barton, E S, Prasad, BVV, Dermody, T S

“…Reovirus virions are nonenveloped icosahedral particles consisting of two concentric protein shells, termed outer capsid and core. Outer-capsid protein sigma 1…”
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Adaptation of Reovirus to Growth in the Presence of Protease Inhibitor E64 Segregates with a Mutation in the Carboxy Terminus of Viral Outer-Capsid Protein sigma 3 by Ebert, D H, Wetzel, J D, Brumbaugh, DE, Chance, SR, Stobie, LE, Baer, G S, Dermody, T S

“…Reovirus virions are internalized into cells by receptor-mediated endocytosis. Within the endocytic compartment, the viral outer capsid undergoes…”
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Persistent reovirus infections of L cells select mutations in viral attachment protein sigma 1 that alter oligomer stability by Wilson, G J, Wetzel, J D, Puryear, W, Bassel-Duby, R, Dermody, T S

“…During maintenance of L-cell cultures persistently infected with reovirus, mutations are selected in viruses and cells. Cells cured of persistent infection…”
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Persistent reovirus infections of L cells select mutations in viral attachment protein sigma1 that alter oligomer stability by Wilson, G J, Wetzel, J D, Puryear, W, Bassel-Duby, R, Dermody, T S

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Detection of reovirus by reverse transcription-polymerase chain reaction using primers corresponding to conserved regions of the viral L1 genome segment by Leary, Thomas P, Erker, James C, Chalmers, Michelle L, Wetzel, J.Denise, Desai, Suresh M, Mushahwar, Isa K, Dermody, Terence S

“…A rapid, reverse transcription-polymerase chain reaction (RT-PCR) procedure for the detection of reovirus RNA in cell culture is described. Total nucleic acids…”
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Mutations in type 3 reovirus that determine binding to sialic acid are contained in the fibrous tail domain of viral attachment protein sigma1 by Chappell, J D, Gunn, V L, Wetzel, J D, Baer, G S, Dermody, T S

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A Comparison of Atomistic and Continuum Approaches to the Study of Bonding Dynamics in Electrocatalysis: Microcantilever Stress and in Situ EXAFS Observations of Platinum Bond Expansion Due to Oxygen Adsorption during the Oxygen Reduction Reaction by Erickson, Evan M, Oruc, Muhammed E, Wetzel, David J, Cason, Michael W, Hoang, Thao T. H, Small, Matthew W, Li, Diya, Frenkel, Anatoly I, Gewirth, Andrew A, Nuzzo, Ralph G

“…Microcantilever stress measurements are examined to contrast and compare their attributes with those from in situ X-ray absorption spectroscopy to elucidate…”
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Viruses and Cells with Mutations Affecting Viral Entry Are Selected during Persistent Rotavirus Infections of MA104 Cells by Mrukowicz, J Z, Wetzel, J D, Goral, M I, Fogo, A B, Wright, P F, Dermody, T S

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Utility of urinary cytology for diagnosing human polyoma virus infection in transplant recipients: A study of 37 cases with electron microscopic analysis by De Las Casas, Luis E., Hoerl, H. Daniel, Bardales, Ricardo H., Pirsch, John D., Sempf, Joan M., Wetzel, Donna J., Stewart III, Jimmie, Oberley, Terry D., Kurtycz, Daniel F.I.

“…Human polyoma virus (HPOV) infection is associated with hemorrhagic cystitis, tubulointerstitial nephritis, and renal transplant dysfunction/allograft loss. We…”
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Brain- and intestine-specific variants of reovirus serotype 3 strain dearing are selected during chronic infection of severe combined immunodeficient mice by Haller, B L, Barkon, M L, Li, X Y, Hu, W M, Wetzel, J D, Dermody, T S, Virgin, 4th, H W

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Binding of type 3 reovirus by a domain of the sigma 1 protein important for hemagglutination leads to infection of murine erythroleukemia cells by Rubin, D H, Wetzel, J D, Williams, W V, Cohen, J A, Dworkin, C, Dermody, T S

“…The recognition of cellular receptors by the mammalian reoviruses is an important determinant of cell and tissue tropism exhibited by reovirus strains of…”
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Reovirus Preferentially Infects the Basolateral Surface and Is Released from the Apical Surface of Polarized Human Respiratory Epithelial Cells by Excoffon, Katherine J. D. A., Guglielmi, Kristen M., Wetzel, J. Denise, Gansemer, Nicholas D., Campbell, Jacquelyn A., Dermody, Terence S., Zabner, Joseph

“…Mammalian reoviruses infect respiratory and gastrointestinal epithelia and cause disease in neonates. Junctional adhesion molecule–A (JAM-A) is a…”
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Peyer's patch dendritic cells process viral antigen from apoptotic epithelial cells in the intestine of reovirus-infected mice by Fleeton, Marina N, Contractor, Nikhat, Leon, Francisco, Wetzel, J Denise, Dermody, Terence S, Kelsall, Brian L

“…We explored the role of Peyer's patch (PP) dendritic cell (DC) populations in the induction of immune responses to reovirus strain type 1 Lang (T1L)…”
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