Search Results - "Wetton, Jon H"

Mitogenome sequences of domestic cats demonstrate lineage expansions and dynamic mutation processes in a mitochondrial minisatellite by Patterson, Emily C, Lall, Gurdeep Matharu, Neumann, Rita, Ottolini, Barbara, Batini, Chiara, Sacchini, Federico, Foster, Aiden P, Wetton, Jon H, Jobling, Mark A

“…Abstract Background As a population genetic tool, mitochondrial DNA is commonly divided into the ~ 1-kb control region (CR), in which single nucleotide variant…”
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Emerging illegal wildlife trade issues: A global horizon scan by Esmail, Nafeesa, Wintle, Bonnie C., t Sas‐Rolfes, Michael, Athanas, Andrea, Beale, Colin M., Bending, Zara, Dai, Ran, Fabinyi, Michael, Gluszek, Sarah, Haenlein, Cathy, Harrington, Lauren A., Hinsley, Amy, Kariuki, Kennedy, Lam, Jack, Markus, Matthew, Paudel, Kumar, Shukhova, Sofiya, Sutherland, William J., Verissimo, Diogo, Wang, Yifu, Waugh, John, Wetton, Jon H., Workman, Catherine, Wright, Joss, Milner‐Gulland, Eleanor J.

“…Illegal wildlife trade is gaining prominence as a threat to biodiversity, but addressing it remains challenging. To help inform proactive policy responses in…”
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Recombination hotspots in an extended human pseudoautosomal domain predicted from double-strand break maps and characterized by sperm-based crossover analysis by Poriswanish, Nitikorn, Neumann, Rita, Wetton, Jon H, Wagstaff, John, Larmuseau, Maarten H D, Jobling, Mark A, May, Celia A

“…The human X and Y chromosomes are heteromorphic but share a region of homology at the tips of their short arms, pseudoautosomal region 1 (PAR1), that supports…”
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Sequencing the orthologs of human autosomal forensic short tandem repeats provides individual- and species-level identification in African great apes by Fedele, Ettore, Wetton, Jon H, Jobling, Mark A

“…Great apes are a global conservation concern, with anthropogenic pressures threatening their survival. Genetic analysis can be used to assess the effects of…”
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In the blood: the myth and reality of genetic markers of identity by Jobling, Mark A., Rasteiro, Rita, Wetton, Jon H.

“…The differences between copies of the human genome are very small, but tend to cluster in different populations. So, despite the fact that low inter-population…”
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Defining end user requirements for a field-based molecular detection system for wildlife forensic investigations by Masters, Alice, Ogden, Rob, Wetton, Jon H., Dawnay, Nick

“…•Identification of end-user requirements for field-based DNA testing in wildlife crime applications.•Instrument and assay performance defined and key species…”
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Massively parallel sequencing of autosomal STRs and identity-informative SNPs highlights consanguinity in Saudi Arabia by Khubrani, Yahya M., Hallast, Pille, Jobling, Mark A., Wetton, Jon H.

“…•Sequences of 27 autosomal STRs and 91 identity-informative SNPs (iiSNPs) generated in 89 Saudi Arabian males.•STR repeat region variants and both STR and…”
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Extensive geographical and social structure in the paternal lineages of Saudi Arabia revealed by analysis of 27 Y-STRs by Khubrani, Yahya M., Wetton, Jon H., Jobling, Mark A.

“…•Yfiler Plus (27-STR) haplotypes reported for 597 Saudi Arabian males.•Discrimination capacity only 74.7% for 17 Yfiler STRs, but increases to 95.3% for Yfiler…”
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A phylogenetic framework facilitates Y-STR variant discovery and classification via massively parallel sequencing by Huszar, Tunde I., Jobling, Mark A., Wetton, Jon H.

“…•23 Y-chromosomal STRs (PPY23) reanalysed by massively parallel sequencing.•Phylogeny-based approach captures wide range of sequence variants in 100…”
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Massively parallel sequencing and capillary electrophoresis of a novel panel of falcon STRs: Concordance with minisatellite DNA profiles from historical wildlife crime by Beasley, Jordan, Shorrock, Guy, Neumann, Rita, May, Celia A., Wetton, Jon H.

“…Birds of prey have suffered persecution for centuries through trapping, shooting, poisoning and theft from the wild to meet the demand from egg collectors and…”
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Sequencing of autosomal, mitochondrial and Y-chromosomal forensic markers in the People of the British Isles cohort detects population structure dominated by patrilineages by Huszar, Tunde I., Bodmer, Walter F., Hutnik, Katarzyna, Wetton, Jon H., Jobling, Mark A.

“…Short tandem repeat (STR) polymorphisms are traditionally assessed by measuring allele lengths via capillary electrophoresis (CE). Massively parallel…”
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Inferring the population of origin of DNA evidence within the UK by allele-specific hybridization of Y-SNPs by Wetton, Jon H., Tsang, Kam W., Khan, Haroon

“…Marked differences in Y-SNP allele frequencies between continental populations can be used to predict the biogeographic origin of a man's ancestral paternal…”
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Analysis of 21 autosomal STRs in Saudi Arabia reveals population structure and the influence of consanguinity by Khubrani, Yahya M., Wetton, Jon H., Jobling, Mark A.

“…•GlobalFiler (21-STR) genotypes reported for 523 Saudi Arabian males.•Significant differences in allele frequencies among five geographical…”
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Defining cat mitogenome variation and accounting for numts via multiplex amplification and Nanopore sequencing by Patterson, Emily C., Lall, Gurdeep Matharu, Neumann, Rita, Ottolini, Barbara, Sacchini, Federico, Foster, Aiden P., Jobling, Mark A., Wetton, Jon H.

“…Hair shed by domestic cats is a potentially useful source of forensic evidence. Analysable hair DNA is predominantly mitochondrial, but the recent…”
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Massively parallel sequencing of sex-chromosomal STRs in Saudi Arabia reveals patrilineage-associated sequence variants by Khubrani, Yahya M., Jobling, Mark A., Wetton, Jon H.

“…•Sequences of 24 Y-STRs and 6 X-STRs generated in 89 Saudi Arabian males.•SNPs and repeat array motifs in Y-STRs are associated with common Middle East…”
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Mitigating the effects of reference sequence bias in single-multiplex massively parallel sequencing of the mitochondrial DNA control region by Huszar, Tunde I., Wetton, Jon H., Jobling, Mark A.

“…•mtDNA control region of 101 diverse samples amplified in a single reaction as 10 overlapping amplicons and sequenced via MPS.•Primers create reference bias,…”
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Geographical structuring and low diversity of paternal lineages in Bahrain shown by analysis of 27 Y-STRs by Al-Snan, Noora R., Messaoudi, Safia A., Khubrani, Yahya M., Wetton, Jon H., Jobling, Mark A., Bakhiet, Moiz

“…We have determined the distribution of Y-chromosomal haplotypes and predicted haplogroups in the ethnically diverse Kingdom of Bahrain, a small archipelago in…”
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Population resequencing of European mitochondrial genomes highlights sex-bias in Bronze Age demographic expansions by Batini, Chiara, Hallast, Pille, Vågene, Åshild J., Zadik, Daniel, Eriksen, Heidi A., Pamjav, Horolma, Sajantila, Antti, Wetton, Jon H., Jobling, Mark A.

“…Interpretations of genetic data concerning the prehistory of Europe have long been a subject of great debate, but increasing amounts of ancient and modern DNA…”
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Subdividing Y-chromosome haplogroup R1a1 reveals Norse Viking dispersal lineages in Britain by Lall, Gurdeep Matharu, Larmuseau, Maarten H D, Wetton, Jon H, Batini, Chiara, Hallast, Pille, Huszar, Tunde I, Zadik, Daniel, Aase, Sigurd, Baker, Tina, Balaresque, Patricia, Bodmer, Walter, Børglum, Anders D, de Knijff, Peter, Dunn, Hayley, Harding, Stephen E, Løvvik, Harald, Dupuy, Berit Myhre, Pamjav, Horolma, Tillmar, Andreas O, Tomaszewski, Maciej, Tyler-Smith, Chris, Verdugo, Marta Pereira, Winney, Bruce, Vohra, Pragya, Story, Joanna, King, Turi E, Jobling, Mark A

“…The influence of Viking-Age migrants to the British Isles is obvious in archaeological and place-names evidence, but their demographic impact has been unclear…”
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Application of a mitochondrial DNA control region frequency database for UK domestic cats by Ottolini, Barbara, Lall, Gurdeep Matharu, Sacchini, Federico, Jobling, Mark A, Wetton, Jon H

“…Highlights • Mitochondrial control region variation is reported for 152 English cats. • A globally rare DNA variant was found in cat hairs on a murder victim…”
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