Liposomes as a model for the study of high frequency dielectrophoresis

Liposomes as a model for the study of high frequency dielectrophoresis

Liposomes were used as a physical model to study the dielectrophoretic response of single‐shelled particles at high frequencies. For a typical particle, the single‐shelled theoretical model predicts a lower cross‐over frequency that depends upon the dielectric properties of the shell and an upper cr...

Full description

Saved in:
Bibliographic Details
Published in:Electrophoresis Vol. 36; no. 13; pp. 1423 - 1428
Main Authors: Hadady, Hanieh, Montiel, Caroline, Wetta, Daniel, Geiger, Emil J.
Format: Journal Article
Language:English
Published: Germany Blackwell Publishing Ltd 01-07-2015
Subjects:
Crossovers
Devices
Dielectric properties
Dielectrophoresis
Electric Conductivity
Electrophoresis
Electrophoresis - methods
High frequencies
High frequency
Liposomes
Liposomes - chemistry
Mathematical models
Microalgae
Models, Chemical
Microalgae
Liposomes
Dielectrophoresis
High frequency
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Liposomes were used as a physical model to study the dielectrophoretic response of single‐shelled particles at high frequencies. For a typical particle, the single‐shelled theoretical model predicts a lower cross‐over frequency that depends upon the dielectric properties of the shell and an upper crossover frequency that depends upon the dielectric properties of the interior. Dried liposomes were rehydrated in media with conductivity ranging from 100 to 2000 μS/cm. The high frequency dielectrophoresis response of the liposomes was observed in the range of 1–80 MHz at 30 volts peak‐to‐peak, and the upper cross‐over frequency was recorded. The experimental results closely matched the theoretical expectations. In particular, the upper cross‐over frequency ranged from 9 to 60 MHz and was found to depend linearly on the interior conductivity of the liposome. These results further confirm the single‐shell model at high‐frequencies. Moreover, they suggest liposomes may be a useful model particle for use during the development of dielectrophoresis‐based devices.
Bibliography:University of Nevada
ark:/67375/WNG-72VX12WW-9
National Science Foundation - No. 1265075
istex:5B98DF7773631633BBCF3043A2973E5BC1E4FEBD
ArticleID:ELPS5464
in colour.
See the article online to view Figs.
and
Colour Online
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0173-0835
1522-2683
DOI:10.1002/elps.201400480