Search Results - "Wetherby, Victoria E"

Intracellular delivery of protein drugs with an autonomously lysing bacterial system reduces tumor growth and metastases by Raman, Vishnu, Van Dessel, Nele, Hall, Christopher L., Wetherby, Victoria E., Whitney, Samantha A., Kolewe, Emily L., Bloom, Shoshana M. K., Sharma, Abhinav, Hardy, Jeanne A., Bollen, Mathieu, Van Eynde, Aleyde, Forbes, Neil S.

“…Critical cancer pathways often cannot be targeted because of limited efficiency crossing cell membranes. Here we report the development of a Salmonella-based…”
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Intracellular Salmonella delivery of an exogenous immunization antigen refocuses CD8 T cells against cancer cells, eliminates pancreatic tumors and forms antitumor immunity by Raman, Vishnu, Howell, Lars M, Bloom, Shoshana M K, Hall, Christopher L, Wetherby, Victoria E, Minter, Lisa M, Kulkarni, Ashish A, Forbes, Neil S

“…Immunotherapies have shown great promise, but are not effective for all tumors types and are effective in less than 3% of patients with pancreatic ductal…”
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