Search Results - "Westwood, B."

Prevalence of the Activating JAK2 Tyrosine Kinase Mutation V617F in the Budd–Chiari Syndrome by Patel, Raj K., Lea, Nicholas C., Heneghan, Michael A., Westwood, Nigel B., Milojkovic, Dragana, Thanigaikumar, Murugaiyan, Yallop, Deborah, Arya, Roopen, Pagliuca, Antonio, Gäken, Joop, Wendon, Julia, Heaton, Nigel D., Mufti, Ghulam J.

“…Background & Aims: Budd–Chiari Syndrome (BCS) results from obstruction to hepatic venous outflow, with myeloproliferative disorder (MPD) accounting for up to…”
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Novel TET2 Mutations Associated With UPD4q24 in Myelodysplastic Syndrome by MOHAMEDALI, Azim M, SMITH, Alexander E, GAKEN, Joop, LEA, Nicholas C, MIAN, Syed A, WESTWOOD, Nigel B, STRUPP, Corinna, GATTERMANN, Norbert, GERMING, Ulrich, MUFTI, Ghulam J

“…Cryptic chromosomal aberrations, such as regions of uniparental disomy (UPD), have been shown to harbor homozygous mutations and are a common feature in…”
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Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the Apc(Min/+) model of colon cancer by Soto-Pantoja, D R, Sipes, J M, Martin-Manso, G, Westwood, B, Morris, N L, Ghosh, A, Emenaker, N J, Roberts, D D

“…Thrombospondin 1 is a glycoprotein that regulates cellular phenotype through interactions with its cellular receptors and extracellular matrix-binding…”
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The role of medical illustration in the evolution of transsphenoidal pituitary surgery by Yu, Sophie E, Westwood, William B, Naples, James G

“…Medical illustration played a crucial, yet often overlooked, role in the evolution of pituitary surgery. From the late 1800s to the present, many preeminent…”
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Dietary fat overcomes the protective activity of thrombospondin-1 signaling in the ApcMin/+ model of colon cancer by Soto-Pantoja, D R, Sipes, J M, Martin-Manso, G, Westwood, B, Morris, N L, Ghosh, A, Emenaker, N J, Roberts, D D

“…Thrombospondin 1 is a glycoprotein that regulates cellular phenotype through interactions with its cellular receptors and extracellular matrix-binding…”
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The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent respiratory toxicity by Thistlethwaite, Fiona C., Gilham, David E., Guest, Ryan D., Rothwell, Dominic G., Pillai, Manon, Burt, Deborah J., Byatte, Andrea J., Kirillova, Natalia, Valle, Juan W., Sharma, Surinder K., Chester, Kerry A., Westwood, Nigel B., Halford, Sarah E. R., Nabarro, Stephen, Wan, Susan, Austin, Eric, Hawkins, Robert E.

“…The primary aim of this clinical trial was to determine the feasibility of delivering first-generation CAR T cell therapy to patients with advanced, CEACAM5 +…”
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Bam Lipoproteins Assemble BamA in Vitro by Hagan, Christine L, Westwood, David B, Kahne, Daniel

“…The Bam machine assembles β-barrel membrane proteins into the outer membranes of Gram-negative bacteria. The central component of the Bam complex, BamA, is a…”
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Inhibition of Angiotensin-Converting Enzyme 2 Exacerbates Cardiac Hypertrophy and Fibrosis in Ren-2 Hypertensive Rats by Trask, Aaron J., Groban, Leanne, Westwood, Brian M., Varagic, Jasmina, Ganten, Detlev, Gallagher, Patricia E., Chappell, Mark C., Ferrario, Carlos M.

“…Background Emerging evidence suggests that cardiac angiotensin-converting enzyme 2 (ACE2) may contribute to the regulation of heart function and…”
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Microarray analysis of tumour antigen expression in presentation acute myeloid leukaemia by Guinn, Barbara-ann, Gilkes, Amanda F., Woodward, Eleanor, Westwood, Nigel B., Mufti, Ghulam J., Linch, David, Burnett, Alan K., Mills, Ken I.

“…Acute myeloid leukaemia (AML) is a difficult to treat disease, especially for those patients who have no eligible haematopoietic stem cell (HSC) donor. One of…”
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Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value by Smith, Alexander E., Mohamedali, Azim M., Kulasekararaj, Austin, Lim, ZiYi, Gäken, Joop, Lea, Nicholas C., Przychodzen, Bartlomiej, Mian, Syed A., Nasser, Erick E., Shooter, Claire, Westwood, Nigel B., Strupp, Corinna, Gattermann, Norbert, Maciejewski, Jaroslaw P., Germing, Ulrich, Mufti, Ghulam J.

“…Mutations in the TET2 gene are frequent in myeloid disease, although their biologic and prognostic significance remains unclear. We analyzed 355 patients with…”
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Serum erythropoietin values in erythrocytoses and in primary thrombocythaemia by Messinezy, Maria, Westwood, Nigel B., El‐Hemaidi, Ihab, Marsden, Joanne T., Sherwood, Roy S., Pearson, Thomas C.

“…Serum erythropoietin (Epo) values were estimated in samples from 125 patients with erythrocytosis to examine the specificity and sensitivity of reduced and…”
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Presence of JAK2 V617F tyrosine kinase mutation as a myeloid-lineage-specific mutation in chronic neutrophilic leukaemia by LEA, N. C, LIM, Z, WESTWOOD, N. B, ARNO, M. J, GÄKEN, J, MOHAMEDALI, A, MUFTI, G. J

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The importance of growth hormone in the regulation of erythropoiesis, red cell mass, and plasma volume in adults with growth hormone deficiency by CHRIST, E. R, CUMMINGS, M. H, WESTWOOD, N. B, SAWYER, B. M, PEARSON, T. C, SÖNKSEN, P. H, RUSSELL-JONES, D. L

“…Total body water (TBW) is reduced in adult GH deficiency (GHD) largely due to a reduction of extracellular water. It is unknown whether total blood volume…”
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Progressive Diastolic Dysfunction in the Female mRen(2).Lewis Rat: Influence of Salt and Ovarian Hormones by Groban, Leanne, Yamaleyeva, Liliya M., Westwood, Brian M., Houle, Timothy T., Lin, Marina, Kitzman, Dalane W., Chappell, Mark C.

“…This study determined the contribution of chronic salt loading and early loss of ovarian hormones on diastolic function in the hypertensive female…”
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Diagnostic applications of haemopoietic progenitor culture techniques in polycythaemias and thrombocythaemias by Westwood, N B, Pearson, T C

“…Clonogenic cultures support the proliferation of haemopoietic cells into colonies of differentiated progeny. Using these techniques it has been established…”
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Professor Tom Connors and the development of novel cancer therapies by the Phase I II Clinical Trials Committee of Cancer Research UK by NEWELL, D. R, SEARLE, K. M, WESTWOOD, N. B, BURTLES, S. S

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A novel pycnometer for density measurements of liquids at elevated temperatures by Westwood, B.M., Kabadi, V.N.

“…A novel pycnometer has been designed for density measurements at elevated temperatures (up to T=473.15 K). The pycnometer consists of a stainless steel cell…”
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Assessment of newspaper reporting of public health and the medical model: a methodological case study by Westwood, Barbara, Westwood, Geoff

“…A case study over a 4-week period reviewed health items reported in the Australian newspaper, The [Brisbane] Courier Mail, under the two broad categories of…”
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The incidences of trisomy 8, trisomy 9 and D20S108 deletion in polycythaemia vera: an analysis of blood granulocytes using interphase fluorescence in situ hybridization by Westwood, N. B., Gruszka‐Westwood, A. M., Pearson, C. E., DeLord, C. F. M., Green, A. R., Huntly, B. J. P., Lakhani, A., McMullin, M. F., Pearson, T. C.

“…We have used interphase fluorescence in situ hybridization (IFISH) to detect trisomy 8, trisomy 9 and 20q deletion in circulating granulocytes from patients…”
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Antiapoptotic Microenvironment of Acute Myeloid Leukemia by Milojkovic, Dragana, Devereux, Stephen, Westwood, Nigel B, Mufti, Ghulam J, Thomas, N. Shaun B, Buggins, Andrea G. S

“…We showed previously that tumor-derived supernatant (TSN) from acute myeloid leukemia (AML) myeloblasts inhibits peripheral blood T cell activation and…”
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