Search Results - "Westphalen, Robert I"

Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: basal release by Westphalen, Robert I, Hemmings, Jr, Hugh C

“…The effects of three volatile anesthetics (isoflurane, enflurane, and halothane) on basal release of glutamate and GABA from isolated rat cerebrocortical nerve…”
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Selective depression by general anesthetics of glutamate versus GABA release from isolated cortical nerve terminals by Westphalen, Robert I, Hemmings, Jr, Hugh C

“…The role of presynaptic mechanisms in general anesthetic depression of excitatory glutamatergic neurotransmission and facilitation of GABA-mediated inhibitory…”
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AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release by Bendor, Jacob, Lizardi-Ortiz, José E, Westphalen, Robert I, Brandstetter, Markus, Hemmings Jr, Hugh C, Sulzer, David, Flajolet, Marc, Greengard, Paul

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The general anesthetic isoflurane depresses synaptic vesicle exocytosis by Hemmings, Jr, Hugh C, Yan, Wayne, Westphalen, Robert I, Ryan, Timothy A

“…General anesthetics have marked effects on synaptic transmission, but the mechanisms of their presynaptic actions are unclear. We used quantitative…”
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Volatile anesthetic effects on glutamate versus GABA release from isolated rat cortical nerve terminals: 4-aminopyridine-evoked release by Westphalen, Robert I, Hemmings, Jr, Hugh C

“…Inhibition of glutamatergic excitatory neurotransmission and potentiation of GABA-mediated inhibitory transmission are possible mechanisms involved in general…”
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Effects of Isoflurane and propofol on glutamate and GABA transporters in isolated cortical nerve terminals by WESTPHALEN, Robert I, HEMMINGS, Hugh C

“…Depression of glutamate-mediated excitatory transmission and potentiation of gamma-aminobutyric acid (GABA)-mediated inhibitory transmission appear to be…”
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AGAP1/AP-3-dependent endocytic recycling of M 5 muscarinic receptors promotes dopamine release by Bendor, Jacob, Lizardi-Ortiz, José E, Westphalen, Robert I, Brandstetter, Markus, Hemmings, Hugh C, Sulzer, David, Flajolet, Marc, Greengard, Paul

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Regional differences in the effects of isoflurane on neurotransmitter release by Westphalen, Robert I., Kwak, No-Bong, Daniels, Keir, Hemmings, Hugh C.

“…Stimulus evoked neurotransmitter release requires that Na + channel-dependent nerve terminal depolarization be transduced into synaptic vesicle exocytosis…”
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Regional differences in nerve terminal Na⁺ channel subtype expression and Na⁺ channel-dependent glutamate and GABA release in rat CNS by Westphalen, Robert I, Yu, Jieying, Krivitski, Margarita, Jih, Ting-Yu, Hemmings Jr, Hugh C

“…J. Neurochem. (2010) 113, 1611-1620. We tested the hypothesis that expression of pre-synaptic voltage-gated sodium channel (Nav) subtypes coupled to…”
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General anesthetics do not affect release of the neuropeptide cholecystokinin from isolated rat cortical nerve terminals by PASHKOV, Victor N, WESTPHALEN, Robert I, HEMMINGS, Hugh C

“…General anesthetics inhibit evoked release of classic neurotransmitters. However, their actions on neuropeptide release in the central nervous system have not…”
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The identification and characterization of excitotoxic nerve-endings in Alzheimer disease by Tannenberg, Rudi K, Scott, Heather L, Westphalen, Robert I, Dodd, Peter R

“…Regionally specific neuronal loss is a distinguishing feature of Alzheimer disease (AD). Excitotoxicity is a mechanism commonly invoked to explain this. We…”
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Regional differences in nerve terminal Na+ channel subtype expression and Na+ channel-dependent glutamate and GABA release in rat central nervous system by Westphalen, Robert I., Yu, Jieying, Krivitski, Margarita, Jih, Ting-Yu, Hemmings, Hugh C.

“…We tested the hypothesis that expression of presynaptic voltage-gated Na + channel (Na v ) subtypes coupled to neurotransmitter release differs between…”
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AGAP1/AP‐3‐dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release by Bendor, Jacob, Lizardi‐Ortiz, José E, Westphalen, Robert I, Brandstetter, Markus, Hemmings, Hugh C, Sulzer, David, Flajolet, Marc, Greengard, Paul

“…Of the five mammalian muscarinic acetylcholine (ACh) receptors, M 5 is the only subtype expressed in midbrain dopaminergic neurons, where it functions to…”
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Selective Depression by Isoflurane and Propofol of Glutamate vs. GABA Release from Isolated Cortical Nerve Terminals: 2002[A-818 by Westphalen, Robert I., Hemmings, Hugh C.

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New evidence for a loss of serotonergic nerve terminals in rats treated with d,l-fenfluramine by Westphalen, R I, Dodd, P R

“…Fenfluramine has been classified as a neurotoxin because animals treated with this anorectic lose 5-HT uptake sites located on serotonergic nerve terminals…”
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Excitotoxic mechanisms in the pathogenesis of dementia by Dodd, P R, Scott, H L, Westphalen, R I

“…Alzheimer disease and related dementias, in common with most major neurological diseases, are characterized by localized brain damage. An abundance of senile…”
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