Search Results - "Westphalen, Christoph Benedikt"

Corrigendum to ‘Single-nucleotide variants, tumour mutational burden and microsatellite instability in patients with metastatic colorectal cancer: Next-generation sequencing results of the FIRE-3 trial’. [European Journal of Cancer 137 (2020) 250–259] by Stahler, Arndt, Stintzing, Sebastian, von Einem, Jobst C., Westphalen (Benedikt), Christoph B., Heinrich, Kathrin, Krämer, Nicole, Michl, Marlies, Modest, Dominik P., Fischer von Weikersthal, Ludwig, Decker, Thomas, Kiani, Alexander, Heintges, Tobias, Kahl, Christoph, Kullmann, Frank, Scheithauer, Werner, Moehler, Markus, Kaiser, Florian, Kirchner, Thomas, Jung, Andreas, Heinemann, Volker

Get full text

Stromal cell-derived factor-1 overexpression induces gastric dysplasia through expansion of stromal myofibroblasts and epithelial progenitors by Shibata, Wataru, Ariyama, Hiroshi, Westphalen, Christoph Benedikt, Worthley, Daniel L, Muthupalani, Sureshkumar, Asfaha, Samuel, Dubeykovskaya, Zinaida, Quante, Michael, Fox, James G, Wang, Timothy C

“…Stromal cell-derived factor-1 (SDF-1/CXCL12), the main ligand for CXCR4, is overexpressed in human cancer. This study addressed the precise contribution of…”
Get more information

Projections of cancer incidence and cancer‐related deaths in Germany by 2020 and 2030 by Quante, Anne S., Ming, Chang, Rottmann, Miriam, Engel, Jutta, Boeck, Stefan, Heinemann, Volker, Westphalen, Christoph Benedikt, Strauch, Konstantin

“…Past patterns of cancer disease and future changes in the demographic structure have a major influence on the projected incidences of human malignancies…”
Get full text

Serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death ligand 1 (sPD-L1) in advanced pancreatic cancer by Kruger, Stephan, Legenstein, Marie-Louise, Rösgen, Verena, Haas, Michael, Modest, Dominik Paul, Westphalen, Christoph Benedikt, Ormanns, Steffen, Kirchner, Thomas, Heinemann, Volker, Holdenrieder, Stefan, Boeck, Stefan

“…Up to now, the efficacy of programmed death protein 1/programmed death ligand 1 (PD-1/PD-L1) blockade in pancreatic cancer (PC) remains uncertain. Serum levels…”
Get full text

Genetically engineered mouse models of pancreatic cancer by Westphalen, Christoph Benedikt, Olive, Kenneth P

“…Pancreatic ductal adenocarcinoma is the 10th most common cancer and the fourth leading cause of cancer-related death in the United States. Despite great…”
Get full text

Patients with colorectal cancer and brain metastasis: The relevance of extracranial metastatic patterns predicting time intervals to first occurrence of intracranial metastasis and survival by Thurmaier, Johannes, Heinemann, Volker, Engel, Jutta, Schubert‐Fritschle, Gabriele, Wiedemann, Max, Nüssler, Natascha C., Ruppert, Reinhard, Kleeff, Jörg, Schepp, Wolfgang, Löhe, Florian, Karthaus, Meinolf, Neumann, Jens, Kumbrink, Jörg, Taverna, Francesco, Stahler, Arndt, Heinrich, Kathrin, Westphalen, Christoph Benedikt, Holch, Julian W., Kirchner, Thomas, Michl, Marlies

“…The aim of the study was to investigate the predictive impact of extracranial metastatic patterns on course of disease and survival in patients with colorectal…”
Get full text

Single-nucleotide variants, tumour mutational burden and microsatellite instability in patients with metastatic colorectal cancer: Next-generation sequencing results of the FIRE-3 trial by Stahler, Arndt, Stintzing, Sebastian, von Einem, Jobst C., Westphalen, Christoph B., Heinrich, Kathrin, Krämer, Nicole, Michl, Marlies, Modest, Dominik P., von Weikersthal, Ludwig Fischer, Decker, Thomas, Kiani, Alexander, Heintges, Tobias, Kahl, Christoph, Kullmann, Frank, Scheithauer, Werner, Moehler, Markus, Kaiser, Florian, Kirchner, Thomas, Jung, Andreas, Heinemann, Volker

“…Molecular biomarkers and primary tumour sidedness guide treatment decisions in metastatic colorectal cancer. Comprehensive molecular profiling aims to identify…”
Get full text

Therapeutic Concepts for Oligometastatic Gastrointestinal Tumours by Ricke, Jens, Westphalen, Christoph Benedikt, Seidensticker, Max

“…Background: Clinical trials have proven a survival benefit from applying local therapies for oligometastatic cancers of various origin. Summary: Today, the…”
Get full text

Mutational profiles of metastatic colorectal cancer treated with FOLFIRI plus cetuximab or bevacizumab before and after secondary resection (AIO KRK 0306; FIRE‐3) by Stahler, Arndt, Heinemann, Volker, Holch, Julian Walter, Einem, Jobst Christian, Westphalen, Christoph Benedikt, Heinrich, Kathrin, Schlieker, Laura, Jelas, Ivan, Alig, Annabel Helga Sophie, Fischer, Laura Elisabeth, Weiss, Lena, Modest, Dominik Paul, Weikersthal, Ludwig Fischer, Decker, Thomas, Kiani, Alexander, Moehler, Markus, Kaiser, Florian, Kirchner, Thomas, Jung, Andreas, Stintzing, Sebastian

“…Secondary resection of metastases is recommended in metastatic colorectal cancer (mCRC). Data describing changes in mutational profiles of corresponding…”
Get full text

Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy by von Baumgarten, Louisa, Kumbrink, Jörg, Jung, Andreas, Reischer, Anna, Flach, Madeleine, Liebmann, Sibylle, Metzeler, Klaus H, Holch, Julian W, Niyazi, Maximilian, Thon, Niklas, Straube, Andreas, von Bergwelt-Baildon, Michael, Heinemann, Volker, Kirchner, Thomas, Westphalen, Christoph Benedikt

“…In the era of precision medicine, cancer treatment is increasingly tailored according to tumor-specific genomic alterations. The analysis of tumor-derived…”
Get full text

Liquid Biopsy in Colorectal Cancer: Quo Vadis? Implementation of Liquid Biopsies in Routine Clinical Patient Care in Two German Comprehensive Cancer Centers by Fischer, Laura E, Stintzing, Sebastian, Heinemann, Volker, Keilholz, Ulrich, Keune, Dietmar, Vollbrecht, Claudia, Burmeister, Thomas, Kind, Andreas, Weiss, Lena, Horst, David, Kirchner, Thomas, Klauschen, Frederick, Jung, Andreas, Westphalen, Christoph Benedikt, Jelas, Ivan

“…The use of liquid biopsies (LB) in patients with solid malignancies enables comprehensive genomic profiling (CGP) of circulating tumor DNA (ctDNA) and has the…”
Get full text

Comparison of somatostatin receptor expression in patients with neuroendocrine tumours with and without somatostatin analogue treatment imaged with [ 18 F]SiTATE by Eschbach, Ralf S, Hofmann, Markus, Späth, Lukas, Sheikh, Gabriel T, Delker, Astrid, Lindner, Simon, Jurkschat, Klaus, Wängler, Carmen, Wängler, Björn, Schirrmacher, Ralf, Tiling, Reinhold, Brendel, Matthias, Wenter, Vera, Dekorsy, Franziska J, Zacherl, Mathias J, Todica, Andrei, Ilhan, Harun, Grawe, Freba, Cyran, Clemens C, Unterrainer, Marcus, Rübenthaler, Johannes, Knösel, Thomas, Paul, Tanja, Boeck, Stefan, Westphalen, Christoph Benedikt, Spitzweg, Christine, Auernhammer, Christoph J, Bartenstein, Peter, Unterrainer, Lena M, Beyer, Leonie

“…Somatostatin analogues (SSA) are frequently used in the treatment of neuroendocrine tumours. Recently, [ F]SiTATE entered the field of somatostatin receptor…”
Get full text

Significance of molecular diagnostics for therapeutic decision-making in recurrent glioma by Blobner, Jens, Dengler, Laura, Blobner, Sven, Eberle, Constantin, Weller, Jonathan, Teske, Nico, Karschnia, Philipp, Rühlmann, Katharina, Heinrich, Kathrin, Ziemann, Frank, Greif, Philipp A, Jeremias, Irmela, Wuerstlein, Rachel, Hasselmann, Korbinian, Dorostkar, Mario, Harter, Patrick N, Quach, Stefanie, Stoecklein, Veit, Albert, Nathalie L, Niyazi, Maximilian, Tonn, Joerg-Christian, Thon, Niklas, Christoph Westphalen, Benedikt, von Baumgarten, Louisa

“…Abstract Background Targeted therapies have substantially improved survival in cancer patients with malignancies outside the brain. Whether in-depth analysis…”
Get full text

P53 Gene Mutation Increases Progastrin Dependent Colonic Proliferation and Colon Cancer Formation in Mice by Ramanathan, Vigneshwaran, Jin, Guangchun, Westphalen, Christoph Benedikt, Whelan, Ashley, Dubeykovskiy, Alexander, Takaishi, Shigeo, Wang, Timothy C.

“…ABSTRACTTransgenic mice overexpressing human progastrin (hGAS) show colonic crypt hyper-proliferation and elevated susceptibility to colon carcinogenesis. We…”
Get full text

Sektorenübergreifende interdisziplinäre Zusammenarbeit der Arbeitsgemeinschaft Internistische Onkologie in der Präzisionsonkologie by Westphalen, Christoph-Benedikt, Quante, Michael, Söhlke, Bärbel, Wartenberg, Markus, Knauf, Wolfgang, Illmer, Thomas, Gökkurt, Eray, Tannapfel, Andrea, Griesinger, Frank, Reinacher-Schick, Anke, Loges, Sonja

Get full text

Panitumumab can safely and effectively be substituted for cetuximab in the treatment of BRAF V600Emut metastatic colorectal cancer (mCRC) – A case series by Rausch, Christian, Schwicht, Charlotte, Doedens, Daphne, Forstpointner, Roswitha, Westphalen, Christoph Benedikt, Heinemann, Volker

Get full text

610: Targeted RT study: results on acute toxicity of targeted therapies and radiotherapy by Konnerth, Dinah, Gaasch, Aurélie, Westphalen, Christoph Benedikt, Heinrich, Kathrin, Niyazi, Maximilian, Eze, Chukwuka, Rogowski, Paul, Marschner, Sebastian Norbert, Zinn, Annemarie, Belka, Claus, Corradini, Stefanie, Schönecker, Stephan

Get full text

Incidence, outcome and risk stratification tools for venous thromboembolism in advanced pancreatic cancer – A retrospective cohort study by Kruger, Stephan, Haas, Michael, Burkl, Carolin, Goehring, Peter, Kleespies, Axel, Roeder, Falk, Gallmeier, Eike, Ormanns, Steffen, Westphalen, Christoph Benedikt, Heinemann, Volker, Rank, Andreas, Boeck, Stefan

“…Abstract Introduction Venous thromboembolism (VTE) is frequent in advanced pancreatic cancer (APC). Recent studies demonstrated that the Khorana score - an…”
Get full text

Bacterial lipopolysaccharide as negative predictor of gemcitabine efficacy in advanced pancreatic cancer – translational results from the AIO-PK0104 Phase 3 study by Guenther, Michael, Haas, Michael, Heinemann, Volker, Kruger, Stephan, Westphalen, Christoph Benedikt, von Bergwelt-Baildon, Michael, Mayerle, Julia, Werner, Jens, Kirchner, Thomas, Boeck, Stefan, Ormanns, Steffen

“…Background Gram-negative bacteria mediated gemcitabine resistance in pre-clinical models. We determined if intratumoural lipopolysaccharide (LPS) detection by…”
Get full text

Highlights of Translational and Molecular Research Presented at the European Society for Medical Oncology Annual Meeting 2023 by Pouyiourou, Maria, Reitnauer, Lea Elisabeth, Ballhausen, Alexej, Alig, Annabel Helga Sophie, Bleckmann, Annalen, Westphalen, Christoph Benedikt, Kloft, Maximilian

Get more information