Search Results - "Weston, Matthew"

Effectiveness of High-Intensity Interval Training (HIT) and Continuous Endurance Training for VO2max Improvements: A Systematic Review and Meta-Analysis of Controlled Trials by Milanović, Zoran, Sporiš, Goran, Weston, Matthew

“…Background Enhancing cardiovascular fitness can lead to substantial health benefits. High-intensity interval training (HIT) is an efficient way to develop…”
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KCN Channels “Cue” Up GABA Release from Astrocytes by Weston, Matthew C.

“…Glial KCNQ K+ Channels Control Neuronal Output by Regulating GABA Release From Glia in C. elegans Graziano B, Wang L, White OR, Kaplan DH, Fernandez-Abascal J,…”
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The Relationships Between Internal and External Measures of Training Load and Intensity in Team Sports: A Meta-Analysis by McLaren, Shaun J., Macpherson, Tom W., Coutts, Aaron J., Hurst, Christopher, Spears, Iain R., Weston, Matthew

“…Background The associations between internal and external measures of training load and intensity are important in understanding the training process and the…”
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The Effects of Repeated-Sprint Training on Field-Based Fitness Measures: A Meta-Analysis of Controlled and Non-Controlled Trials by Taylor, Jonathan, Macpherson, Tom, Spears, Iain, Weston, Matthew

“…Background Repeated-sprint training appears to be an efficient and practical means for the simultaneous development of different components of fitness relevant…”
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Distinct Features of Interictal Activity Predict Seizure Localization and Burden in a Mouse Model of Childhood Epilepsy by Tobin, William F, Weston, Matthew C

“…The epileptic brain is distinguished by spontaneous seizures and interictal epileptiform discharges (IEDs). Basic patterns of mesoscale brain activity outside…”
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Experimental observation of the liquid-liquid transition in bulk supercooled water under pressure by Kim, Kyung Hwan, Amann-Winkel, Katrin, Giovambattista, Nicolas, Späh, Alexander, Perakis, Fivos, Pathak, Harshad, Parada, Marjorie Ladd, Yang, Cheolhee, Mariedahl, Daniel, Eklund, Tobias, Lane, Thomas J, You, Seonju, Jeong, Sangmin, Weston, Matthew, Lee, Jae Hyuk, Eom, Intae, Kim, Minseok, Park, Jaeku, Chun, Sae Hwan, Poole, Peter H, Nilsson, Anders

“…We prepared bulk samples of supercooled liquid water under pressure by isochoric heating of high-density amorphous ice to temperatures of 205 ± 10 kelvin,…”
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Identification of diverse astrocyte populations and their malignant analogs by John Lin, Chia-Ching, Yu, Kwanha, Hatcher, Asante, Huang, Teng-Wei, Lee, Hyun Kyoung, Carlson, Jeffrey, Weston, Matthew C, Chen, Fengju, Zhang, Yiqun, Zhu, Wenyi, Mohila, Carrie A, Ahmed, Nabil, Patel, Akash J, Arenkiel, Benjamin R, Noebels, Jeffrey L, Creighton, Chad J, Deneen, Benjamin

“…The nature of astrocyte diversity in the adult brain has remained poorly defined. The authors identify five astrocyte subpopulations in the brain that exhibit…”
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Interplay between VGLUT Isoforms and Endophilin A1 Regulates Neurotransmitter Release and Short-Term Plasticity by Weston, Matthew C., Nehring, Ralf B., Wojcik, Sonja M., Rosenmund, Christian

“…Vesicular glutamate transporters (VGLUTs) are essential for filling synaptic vesicles with glutamate and mammals express three VGLUT isoforms (VGLUT1–3) with…”
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Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission by Weston, Matthew C, Chen, Hongmei, Swann, John W

“…The mammalian target of rapamycin (mTOR) signaling pathway in neurons integrates a variety of extracellular signals to produce appropriate translational…”
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mTORC2 Inhibition Improves Morphological Effects of PTEN Loss, But Does Not Correct Synaptic Dysfunction or Prevent Seizures by Cullen, Erin R, Tariq, Kamran, Shore, Amy N, Luikart, Bryan W, Weston, Matthew C

“…Hyperactivation of PI3K/PTEN-mTOR signaling during neural development is associated with focal cortical dysplasia (FCD), autism, and epilepsy. mTOR can signal…”
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Hyperactivity of mTORC1- and mTORC2-dependent signaling mediates epilepsy downstream of somatic PTEN loss by Cullen, Erin R, Safari, Mona, Mittelstadt, Isabelle, Weston, Matthew C

“…Gene variants that hyperactivate PI3K-mTOR signaling in the brain lead to epilepsy and cortical malformations in humans. Some gene variants associated with…”
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The effect of 12 weeks of combined upper- and lower-body high-intensity interval training on muscular and cardiorespiratory fitness in older adults by Hurst, Christopher, Weston, Kathryn L., Weston, Matthew

“…Background High-intensity interval training (HIT) can impact cardiorespiratory and muscular fitness simultaneously, yet protocols typically focus on lower-body…”
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PSPI: A deep learning approach for prokaryotic small protein identification by Weston, Matthew, Hu, Haiyan, Li, Xiaoman

“…Small Proteins (SPs) are pivotal in various cellular functions such as immunity, defense, and communication. Despite their significance, identifying them is…”
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The effects of same-session combined exercise training on cardiorespiratory and functional fitness in older adults: a systematic review and meta-analysis by Hurst, Christopher, Weston, Kathryn L., McLaren, Shaun J., Weston, Matthew

“…Endurance and strength training are effective strategies for counteracting age-associated reductions in physical performance in older adults, with a…”
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A tRNA Variant Translates Into Seizure Resistance by Weston, Matthew C.

“…Expression of the Neuronal tRNA n-Tr20 Regulates Synaptic Transmission and Seizure Susceptibility Kapur M, Ganguly A, Nagy G, Adamson SI, Chuang JH, Frankel…”
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The Heated Relationship Between Neural Activity and Seizures by Weston, Matthew C.

“…Interneuron Desynchronization Precedes Seizures in a Mouse Model of Dravet Syndrome Tran CH, Vaiana M, Nakuci J, et al. J Neurosci. 2020 Mar…”
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Evaluating intervention fidelity: an example from a high-intensity interval training study by Taylor, Kathryn L, Weston, Matthew, Batterham, Alan M

“…Intervention fidelity refers to the degree to which an experimental manipulation has been implemented as intended, but simple, robust methods for quantifying…”
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Intensities of exercise during match-play in FA Premier League referees and players by Weston, Matthew, Drust, Barry, Gregson, Warren

“…The aim of the present study was to examine the relationship between intensities of exercise during match-play of elite-standard soccer referees with those of…”
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Altered excitatory transmission onto hippocampal interneurons in the IQSEC2 mouse model of X-linked neurodevelopmental disease by Sah, Megha, Shore, Amy N., Petri, Sabrina, Kanber, Ayla, Yang, Mu, Weston, Matthew C., Frankel, Wayne N.

“…Mutations in the X-linked gene IQSEC2 are associated with multiple cases of epilepsy, epileptic encephalopathy, intellectual disability and autism spectrum…”
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Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission by McCabe, Matthew P, Cullen, Erin R, Barrows, Caitlynn M, Shore, Amy N, Tooke, Katherine I, Laprade, Kathryn A, Stafford, James M, Weston, Matthew C

“…Although mTOR signaling is known as a broad regulator of cell growth and proliferation, in neurons it regulates synaptic transmission, which is thought to be a…”
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