Search Results - "Weston, Douglas"

Heterogeneity of enrolment criteria for ongoing smouldering myeloma trials by Soomro, Mohammad Ahsen, Hoffman, James, Goodman, Aaron Michael, Sborov, Douglas Weston, Mohyuddin, Ghulam Rehman

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Early postnatal exposure to ultrafine particulate matter air pollution: persistent ventriculomegaly, neurochemical disruption, and glial activation preferentially in male mice by Allen, Joshua L, Liu, Xiufang, Pelkowski, Sean, Palmer, Brian, Conrad, Katherine, Oberdörster, Günter, Weston, Douglas, Mayer-Pröschel, Margot, Cory-Slechta, Deborah A

“…Air pollution has been associated with adverse neurological and behavioral health effects in children and adults. Recent studies link air pollutant exposure to…”
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Sex-dependent impacts of low-level lead exposure and prenatal stress on impulsive choice behavior and associated biochemical and neurochemical manifestations by Weston, Hiromi I., Weston, Douglas D., Allen, Joshua L., Cory-Slechta, Deborah A.

“…•Pb±PS reduced impulsive choice behavior of male offspring at the indifference point in a delay discounting task.•Pb±PS slowed acquisition of impulsive choice…”
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Developmental Exposure to Concentrated Ambient Ultrafine Particulate Matter Air Pollution in Mice Results in Persistent and Sex-Dependent Behavioral Neurotoxicity and Glial Activation by Allen, Joshua L., Liu, Xiufang, Weston, Douglas, Prince, Lisa, Oberdörster, Günter, Finkelstein, Jacob N., Johnston, Carl J., Cory-Slechta, Deborah A.

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Developmental exposure to concentrated ambient ultrafine particulate matter air pollution in mice results in persistent and sex-dependent behavioral neurotoxicity and glial activation by Allen, Joshua L, Liu, Xiufang, Weston, Douglas, Prince, Lisa, Oberdörster, Günter, Finkelstein, Jacob N, Johnston, Carl J, Cory-Slechta, Deborah A

“…The brain appears to be a target of air pollution. This study aimed to further ascertain behavioral and neurobiological mechanisms of our previously observed…”
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Oncolytic virus pelareorep plus carfilzomib phase I trial in carfilzomib-refractory patients (NCI 9603): Responses with cytokine storm by Sborov, Douglas Weston, Viola, Domenico, Dona, Ada A, Nooka, Ajay K., Kaufman, Jonathan L., Lonial, Sagar, Boise, Lawrence, Dhodapkar, Madhav V., Joseph, Nisha, Pichiorri, Flavia, Hofmeister, Craig C.

“…Abstract only 8535 Background: Viral oncolytic therapy with intravenous Pelareorep, the infusible form of reovirus, is supported by preclinical data indicating…”
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Consequences of developmental exposure to concentrated ambient ultrafine particle air pollution combined with the adult paraquat and maneb model of the Parkinson's disease phenotype in male mice by ALLEN, Joshua L, XIUFANG LIU, WESTON, Douglas, CONRAD, Katherine, OBERDÖRSTER, Günter, CORY-SLECHTA, Deborah A

“…Current evidence suggests suceptibility of both the substantia nigra and striatum to exposure to components of air pollution. Further, air pollution has been…”
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Pivotal DREAMM-2 study: Single-agent belantamab mafodotin (GSK2857916) in patients with relapsed/refractory multiple myeloma (RRMM) refractory to proteasome inhibitors (PIs), immunomodulatory agents, and refractory and/or intolerant to anti-CD38 monoclonal antibodies (mAbs) by Lonial, Sagar, Lee, Hans Chulhee, Badros, Ashraf, Trudel, Suzanne, Nooka, Ajay K., Chari, Ajai, Abdallah, Al-Ola A., Callander, Natalie Scott, Sborov, Douglas Weston, Suvannasankha, Attaya, Weisel, Katja, Voorhees, Peter Michael, Hoos, Axel, Zhi, Eric, Baron, January, Piontek, Trisha, Jewell, Roxanne C., Opalinska, Joanna, Gupta, Ira, Cohen, Adam D.

“…Abstract only 8536 Background: Single-agent belantamab mafodotin (B-cell maturation antigen targeting immunoconjugate) showed clinically meaningful activity…”
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DREAMM-2: Single-agent belantamab mafodotin (GSK2857916) in patients with relapsed/refractory multiple myeloma (RRMM) and renal impairment by Lee, Hans Chulhee, Cohen, Adam D., Chari, Ajai, Hultcrantz, Malin, Nooka, Ajay K., Callander, Natalie Scott, Suvannasankha, Attaya, Badros, Ashraf, Libby, Edward N., Trudel, Suzanne, Richardson, Paul G., Sborov, Douglas Weston, Rodríguez Otero, Paula, Lonial, Sagar, Zhi, Eric, Lewis, Eric, Gupta, Ira, Opalinska, Joanna

“…Abstract only 8519 Background: Renal impairment, a frequent complication and poor prognostic factor in RRMM, often leads to poor tolerability of standard…”
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Variations in the nature of behavioral experience can differentially alter the consequences of developmental exposures to lead, prenatal stress, and the combination by Cory-Slechta, Deborah A, Merchant-Borna, Kian, Allen, Joshua L, Liu, Sue, Weston, Douglas, Conrad, Katherine

“…Behavioral experience (BE) can critically influence later behavior and brain function, but the central nervous system (CNS) consequences of most developmental…”
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Brain hemispheric differences in the neurochemical effects of lead, prenatal stress, and the combination and their amelioration by behavioral experience by Cory-Slechta, Deborah A, Weston, Douglas, Liu, Sue, Allen, Joshua L

“…Brain lateralization, critical to mediation of cognitive functions and to "multitasking," is disrupted in conditions such as attention deficit disorder and…”
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A feasibility study of electronic geriatric assessment for real-time morbidity evaluation by Bhatt, Geetika, Hofmeister, Craig C., Efebera, Yvonne Adeduni, Benson, Don M., Sborov, Douglas Weston, Jaglowski, Samantha Mary, Devine, Steven Michael, Wildes, Tanya Marya, Jones, Desiree, Huang, Ying, Rosko, Ashley Elizabeth

“…Abstract only…”
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Lifetime Consequences of Combined Maternal Lead and Stress by Cory‐Slechta, Deborah A., Virgolini, Miriam B., Rossi‐George, Alba, Thiruchelvam, Mona, Lisek, Renata, Weston, Douglas

“…:  Elevated lead (Pb) exposure and high stress both target low socio‐economic status populations. Both also act on the hypothalamic–pituitary–adrenal (HPA)…”
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MM-219: Pivotal DREAMM-2 Study: Single-Agent Belantamab Mafodotin (Belamaf; GSK2857916) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM) Refractory to Proteasome Inhibitors and Immunomodulatory Agents, and Refractory and/or Intolerant to Anti-CD38 Monoclonal Antibodies (mAbs), Including Subgroups with Renal Impairment (RI) and High-Risk (HR) Cytogenetics by Lonial, Sagar, Lee, Hans Chulhee, Badros, Ashraf, Trudel, Suzanne, Nooka, Ajay K, Chari, Ajai, Abdallah, Al-Ola, Callander, Natalie Scott, Sborov, Douglas Weston, Suvannasankha, Attaya, Weisel, Katja, Voorhees, Peter M, Hultcrantz, Malin, Libby, Edward N, Richardson, Paul G, Otero, Paula Rodriguez, Besemer, Britta, Facon, Thierry, Hoos, Axel, Zhi, Eric, Baron, January, Piontek, Trisha, Jewell, Roxanne C, Lewis, Eric, Opalinska, Joanna, Gupta, Ira, Cohen, Adam D

“…Belamaf showed deep and durable single-agent activity in the pivotal DREAMM-2 study primary analysis (NCT03525678) (1–7) in a patient population that…”
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A phase 1 study of AR-42 in patients with advanced solid tumors, including nervous system tumors by Valencia, Hugo, Newton, Herbert B., Hade, Erinn, Sborov, Douglas Weston, Cavaliere, Robert, Poi, Ming, Phelps, Mitch, Wang, Jiang, Coss, Christopher C, Khountham, Soun, Monk, Paul, Olencki, Thomas, Shapiro, Charles L, Piekarz, Richard, Hofmeister, Craig C., Grever, Michael R., Welling, D. Bradley, Mortazavi, Amir

“…Abstract only…”
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Geology and economic significance of Pleistocene channel and terrace deposits on the San Diego mainland shelf, California by Sprague, Douglas Weston

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