Search Results - "Westlye, Lars T."
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The structure of the cerebral cortex across adult life: age-related patterns of surface area, thickness, and gyrification
Published in Cerebral cortex (New York, N.Y. 1991) (01-11-2013)“…Older adults exhibit global reductions in cortical surface area, but little is known about the regional patterns of reductions or how these relate to other…”
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White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction
Published in NeuroImage (Orlando, Fla.) (01-01-2021)“…The macro- and microstructural architecture of human brain white matter undergoes substantial alterations throughout development and ageing. Most of our…”
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3
The correlation between central and peripheral oxytocin concentrations: A systematic review and meta-analysis
Published in Neuroscience and biobehavioral reviews (01-07-2017)“…•There was a positive association between central and peripheral oxytocin concentrations.•This association was moderated by experimental context.•No…”
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Oxytocin pathway gene networks in the human brain
Published in Nature communications (08-02-2019)“…Oxytocin is a neuropeptide involved in animal and human reproductive and social behavior. Three oxytocin signaling genes have been frequently implicated in…”
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Accelerated changes in white matter microstructure during aging: a longitudinal diffusion tensor imaging study
Published in The Journal of neuroscience (12-11-2014)“…It is well established that human brain white matter structure changes with aging, but the timescale and spatial distribution of this change remain uncertain…”
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Accelerating cortical thinning: unique to dementia or universal in aging?
Published in Cerebral cortex (New York, N.Y. 1991) (01-04-2014)“…Does accelerated cortical atrophy in aging, especially in areas vulnerable to early Alzheimer's disease (AD), unequivocally signify neurodegenerative disease…”
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Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study
Published in NeuroImage (Orlando, Fla.) (15-11-2020)“…•Cardiovascular risk factors are associated with older brain age.•Blood pressure is more strongly associated with white matter compared to gray matter.•Resting…”
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Population-based neuroimaging reveals traces of childbirth in the maternal brain
Published in Proceedings of the National Academy of Sciences - PNAS (29-10-2019)“…Maternal brain adaptations have been found across pregnancy and postpartum, but little is known about the long-term effects of parity on the maternal brain…”
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Brain Maturation in Adolescence and Young Adulthood: Regional Age-Related Changes in Cortical Thickness and White Matter Volume and Microstructure
Published in Cerebral cortex (New York, N.Y. 1991) (01-03-2010)“…The development of cortical gray matter, white matter (WM) volume, and WM microstructure in adolescence is beginning to be fairly well characterized by…”
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Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging
Published in Human brain mapping (15-04-2021)“…The concept of brain maintenance refers to the preservation of brain integrity in older age, while cognitive reserve refers to the capacity to maintain…”
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Understanding the genetic determinants of the brain with MOSTest
Published in Nature communications (14-07-2020)“…Regional brain morphology has a complex genetic architecture, consisting of many common polymorphisms with small individual effects. This has proven…”
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Network-specific effects of age and in-scanner subject motion: A resting-state fMRI study of 238 healthy adults
Published in NeuroImage (Orlando, Fla.) (15-11-2012)“…Cognitive aging is accompanied by a range of structural and functional differences in the brain, even in the absence of neurodegenerative disease. Functional…”
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13
In Vivo Hippocampal Subfield Volumes in Schizophrenia and Bipolar Disorder
Published in Biological psychiatry (1969) (15-03-2015)“…Abstract Background Hippocampal dysfunction and volume reductions have been reported in patients with schizophrenia and bipolar disorder. The hippocampus…”
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Memory training impacts short-term changes in aging white matter: A Longitudinal Diffusion Tensor Imaging Study
Published in Human brain mapping (01-10-2012)“…A growing body of research indicates benefits of cognitive training in older adults, but the neuronal mechanisms underlying the effect of cognitive…”
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Heterogeneity in Subcortical Brain Development: A Structural Magnetic Resonance Imaging Study of Brain Maturation from 8 to 30 Years
Published in The Journal of neuroscience (23-09-2009)“…Brain development during late childhood and adolescence is characterized by decreases in gray matter (GM) and increases in white matter (WM) and ventricular…”
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Effects of memory training on cortical thickness in the elderly
Published in NeuroImage (Orlando, Fla.) (01-10-2010)“…The brain's ability to alter its functional and structural architecture in response to experience and learning has been extensively studied. Mental stimulation…”
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Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease
Published in Nature genetics (01-05-2015)“…Stacy Steinberg, Hreinn Stefansson, Thorlakur Jonsson and colleagues found that rare variants predicted to alter the function of ABCA7 are associated with risk…”
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Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology
Published in NeuroImage (Orlando, Fla.) (01-12-2021)“…•Genetic variants affecting one cortical region often affect other cortical regions.•Standard mass-univariate methods ignore the distributed nature of genetic…”
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Waves of Maturation and Senescence in Micro-structural MRI Markers of Human Cortical Myelination over the Lifespan
Published in Cerebral cortex (New York, N.Y. 1991) (01-03-2019)“…Abstract Seminal human brain histology work has demonstrated developmental waves of myelination. Here, using a micro-structural magnetic resonance imaging…”
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The maternal brain: Region‐specific patterns of brain aging are traceable decades after childbirth
Published in Human brain mapping (01-11-2020)“…Pregnancy involves maternal brain adaptations, but little is known about how parity influences women's brain aging trajectories later in life. In this study,…”
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