Search Results - "Westler, W. M"

A22 Disrupts the Bacterial Actin Cytoskeleton by Directly Binding and Inducing a Low-Affinity State in MreB by Bean, G. J, Flickinger, S. T, Westler, W. M, McCully, M. E, Sept, D, Weibel, D. B, Amann, K. J

“…S-(3,4-Dichlorobenzyl)isothiourea (A22) disrupts the actin cytoskeleton of bacteria, causing defects of morphology and chromosome segregation. Previous studies…”
Get full text

Natural J-Coupling Analysis:  Interpretation of Scalar J-Couplings in Terms of Natural Bond Orbitals by Wilkens, Steven J, Westler, William M, Markley, John L, Weinhold, Frank

“…The natural J-coupling (NJC) method presented here analyzes the Fermi contact portion of J-coupling in the framework of finite perturbation theory applied to…”
Get full text

Chemical structure of the hexapeptide chromophore of the Aequorea green-fluorescent protein by Cody, Chris W, Prasher, Douglas C, Westler, William M, Prendergast, Franklyn G, Ward, William W

“…The green-fluorescent proteins (GFP) are a unique class of proteins involved in bioluminescence of many cnidaria. The GFPs serve as energy-transfer acceptors,…”
Get full text

Specificity, stability, and potency of monocyclic β-lactam inhibitors of human leucocyte elastase by KNIGHT, W. B, GREEN, B. G, HAGMANN, W. K, HALE, J. J, LIESCH, J, MACCOSS, M, NAVIA, M. A, SHAH, S. K, UNDERWOOD, D, DOHERTY, J. B, CHABIN, R. M, GALE, P, MAYCOCK, A. L, WESTON, H, KUO, D. W, WESTLER, W. M, DORN, C. P, FINKE, P. E

“…Stable, potent, highly specific, time-dependent monocyclic beta-lactam inhibitors of human leucocyte elastase (HLE) are described. The heavily substituted…”
Get full text

Practical introduction to theory and implementation of multinuclear, multidimensional nuclear magnetic resonance experiments by Edison, A S, Abildgaard, F, Westler, W M, Mooberry, E S, Markley, J L

Get more information

Comparison of the accuracy of protein solution structures derived from conventional and network‐edited NOESY data by Hoogstraten, Charles G., Choe, Soheui, Westler, William M., Markley, John L.

“…Network‐editing experiments are variants of the basic NOESY experiment that allow more accurate direct measurement of interproton distances in macromolecules…”
Get full text

Specificity, stability, and potency of monocyclic .beta.-lactam inhibitors of human leukocyte elastase by Knight, W. B, Green, B. G, Chabin, R. M, Gale, P, Maycock, A. L, Weston, H, Kuo, D. W, Westler, W. M, Dorn, C. P

Get full text

NMR studies of retinoid-protein interactions : The conformation of [13C]-β-ionones bound to β-lactoglobulin B by CURLEY, R. W, SUNDARAM, A. K, FOWBLE, J. W, ABILDGAARD, F, WESTLER, W. M, MARKLEY, J. L

“…Vitamin A (retinol) and its metabolites comprise the natural retinoids. While the biological action of these molecules are thought to be primarily mediated by…”
Get full text

Solution Structure of a Type I Dockerin Domain, a Novel Prokaryotic, Extracellular Calcium-binding Domain by Lytle, Betsy L., Volkman, Brian F., Westler, William M., Heckman, Matthew P., Wu, J.H.David

“…The type I dockerin domain is responsible for incorporating its associated glycosyl hydrolase into the bacterial cellulosome, a multienzyme cellulolytic…”
Get full text

Fractionation Factors and Activation Energies for Exchange of the Low Barrier Hydrogen Bonding Proton in Peptidyl Trifluoromethyl Ketone Complexes of Chymotrypsin by Lin, Jing, Westler, William M., Cleland, W. Wallace, Markley, John L., Frey, Perry A.

“…NMR investigations have been carried out of complexes between bovine chymotrypsin Aαand a series of four peptidyl trifluoromethyl ketones, listed here in order…”
Get full text

Protonation-State Dependence of Hydrogen Bond Strengths and Exchange Rates in a Serine Protease Catalytic Triad:  Bovine Chymotrypsinogen A by Markley, John L, Westler, William M

“…Hydrogen-1 nuclear magnetic resonance spectroscopy was used to measure D/H fractionation factors and the temperature dependence of the rate of hydrogen…”
Get full text

Correlation of carbon-13 and nitrogen-15 chemical shifts in selectively and uniformly labeled proteins by heteronuclear two-dimensional NMR spectroscopy by Westler, William M, Stockman, Brian J, Hosoya, Yoshiko, Miyake, Yoko, Kainosho, Masatsune, Markley, John L

Get full text

Two-dimensional correlated spectroscopy (COSY) of intact frog muscle: spectral pattern characterization and lactate quantitation by Alonso, J, Arús, C, Westler, W M, Markley, J L

“…Two-dimensional scalar-correlated 1H spectra (COSY) were recorded from a model solution containing varying amounts of lactate and a fixed concentration of…”
Get more information

Secondary Structure and Calcium-Induced Folding of the Clostridium thermocellum Dockerin Domain Determined by NMR Spectroscopy by Lytle, Betsy L, Volkman, Brian F, Westler, William M, Wu, J.H.David

“…Assembly of the cellulosome, a large, extracellular cellulase complex, depends upon docking of a myriad of enzymatic subunits to homologous receptors, or…”
Get full text

Refinement of the NMR solution structure of a protein to remove distortions arising from neglect of internal motion by Fejzo, Jasna, Krezel, Andrzej M, Westler, William M, Macura, Slobodan, Markley, John L

“…The effect of internal motion on the quality of a protein structure derived from nuclear magnetic resonance (NMR) cross relaxation has been investigated…”
Get full text

Effects of Serpin Binding on the Target Proteinase:  Global Stabilization, Localized Increased Structural Flexibility, and Conserved Hydrogen Bonding at the Active Site by Kaslik, Gyula, Kardos, József, Szabó, Erika, Szilágyi, László, Závodszky, Péter, Westler, William M, Markley, John L, Gráf, László

“…The binding of human α1-proteinase inhibitor to rat trypsin was shown by NMR spectroscopy to raise the pK a‘ of His57 in the active site but not to disrupt the…”
Get full text

Detection and characterization of hyperfine-shifted resonances in the proton nuclear magnetic resonance spectrum of Anabaena 7120 ferredoxin at high magnetic fields by Skjeldal, L, Westler, W M, Markley, J L

“…This paper presents previously unobserved signals in the 1H NMR spectra of oxidized and reduced [2Fe-2S]-ferredoxin from Anabaena 7120 detected at 400, 500,…”
Get more information

Flavodoxin from Anabaena 7120: uniform nitrogen-15 enrichment and hydrogen-1, nitrogen-15, and phosphorus-31 NMR investigations of the flavin mononucleotide binding site in the reduced and oxidized states by Stockman, Brian J, Westler, William M, Mooberry, Eddie S, Markley, John L

“…Interactions between flavin mononucleotide (FMN) and apoprotein have been investigated in the reduced and oxidized states of the flavodoxin isolated from…”
Get full text

Novel entries in a fungal biofilm matrix encyclopedia by Zarnowski, Robert, Westler, William M, Lacmbouh, Ghislain Ade, Marita, Jane M, Bothe, Jameson R, Bernhardt, Jörg, Lounes-Hadj Sahraoui, Anissa, Fontaine, Joël, Sanchez, Hiram, Hatfield, Ronald D, Ntambi, James M, Nett, Jeniel E, Mitchell, Aaron P, Andes, David R

“…Virulence of Candida is linked with its ability to form biofilms. Once established, biofilm infections are nearly impossible to eradicate. Biofilm cells live…”
Get full text

Assignment of the 13C-NMR spectra of virgin and reactive-site modified turkey ovomucoid third domain by Robertson, A D, Rhyu, G I, Westler, W M, Markley, J L

“…The virgin (reactive-site Leu18-Glu19 peptide bond intact) and modified (reactive-site Leu18-Glu19 peptide bond hydrolyzed) forms of turkey ovomucoid third…”
Get more information