Search Results - "Westermark, P"

Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis by Eldhagen, P., Berg, S., Lund, L.H., Sörensson, P., Suhr, O.B., Westermark, P.

“…Background Wild‐type transthyretin (ATTRwt) amyloidosis is the most common systemic amyloidosis in Western countries and manifests mainly as progressive…”
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One mutation, two distinct disease variants: unravelling the impact of transthyretin amyloid fibril composition by Suhr, O. B., Lundgren, E., Westermark, P.

“…Although hereditary transthyretin (h‐ATTR) amyloidosis is a monogenetic disease, a large variation in its phenotype has been observed. The common hypothesis of…”
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The systemic amyloidoses: clearer understanding of the molecular mechanisms offers hope for more effective therapies by Merlini, G, Westermark, P

“… Knowledge about the systemic amyloidoses has increased considerably during the last few years. This group of diseases is characterized by great biochemical…”
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Amyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosis by Ihse, E, Ybo, A, Suhr, OB, Lindqvist, P, Backman, C, Westermark, P

“…Swedish familial systemic amyloidosis with polyneuropathy (FAP) depends on a mutation leading to a methionine-for-valine substitution in transthyretin. The…”
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Serum amyloid A and protein AA: Molecular mechanisms of a transmissible amyloidosis by Westermark, Gunilla T., Westermark, Per

“…Systemic AA-amyloidosis is a complication of chronic inflammatory diseases and the fibril protein AA derives from the acute phase reactant serum AA…”
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Transmissible amyloid by Tjernberg, L.O., Rising, A., Johansson, J., Jaudzems, K., Westermark, P.

“…There are around 30 human diseases associated with protein misfolding and amyloid formation, each one caused by a certain protein or peptide. Many of these…”
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Changes in pathological and biochemical findings of systemic tissue sites in familial amyloid polyneuropathy more than 10 years after liver transplantation by Oshima, Toshinori, Kawahara, Satomi, Ueda, Mitsuharu, Kawakami, Yushi, Tanaka, Rina, Okazaki, Takahiro, Misumi, Yohei, Obayashi, Konen, Yamashita, Taro, Ohya, Yuki, Ihse, Elisabet, Shinriki, Satoru, Tasaki, Masayoshi, Jono, Hirofumi, Asonuma, Katsuhiro, Inomata, Yukihiro, Westermark, Per, Ando, Yukio

“…Objective To elucidate the long-term effects of liver transplantation (LT) on familial amyloid polyneuropathy (FAP). Methods We investigated…”
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Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets by Paulsson, J F, Andersson, A, Westermark, P, Westermark, G T

“…Islet amyloid is a frequent finding in the islets of Langerhans of individuals with type 2 diabetes. The main amyloid constituent is the beta cell-derived…”
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Amyloid detection and typing: summary of current practice and recommendations of the consensus group by Picken, M. M., Westermark, P.

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The pathogenesis of amyloidosis : Understanding general principles by WESTERMARK, P

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Aspects on human amyloid forms and their fibril polypeptides by Westermark, Per

“…Amyloid is an in vivo fibrillar substance containing a fibril protein and several additional molecules. Presently, 25 proteins have been reported as main…”
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Alkali-Degradation of Amyloid: An Ancient Method Useful for Making Monoclonal Antibodies Against Amyloid Fibril Proteins by Westermark, G.T, Sletten, K, Westermark, P

“…The systemic amyloidoses constitute a group of life-threatening disorders at which one out of about 15 different proteins have polymerized into fibrils…”
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Mathematical modeling in chronobiology by Bordyugov, G, Westermark, P O, Korenčič, A, Bernard, S, Herzel, H

“…Circadian clocks are autonomous oscillators entrained by external Zeitgebers such as light-dark and temperature cycles. On the cellular level, rhythms are…”
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Nature of os labrum-associated amyloid deposits by Murphy, C., Wang, S., Macy, S., Makovitzky, J., Athanasou, N., Westermark, P., Weiss, D. T., Solomon, A.

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Islet Amyloid Polypeptide: Pinpointing Amino Acid Residues Linked to Amyloid Fibril Formation by Westermark, Per, Engström, Ulla, Johnson, Kenneth H., Westermark, Gunilla T., Betsholtz, Christer

“…Islet amyloid polypeptide (IAPP), a putative polypeptide hormone, is a product of pancreatic β-cells and the major constituent of the amyloid deposits seen…”
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Amyloid Fibrils in Human Insulinoma and Islets of Langerhans of the Diabetic Cat are Derived from a Neuropeptide-Like Protein also Present in Normal Islet Cells by WESTERMARK, P, WERNSTEDT, C, WILANDER, E, HAYDEN, D. W, O'BRIEN, T. D, JOHNSON, K. H

“…Amyloid deposits localized to the islets of Langerhans are typical of non-insulin-dependent human diabetes mellitus and of diabetes mellitus in adult cats…”
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Fibril in Senile Systemic Amyloidosis is Derived from Normal Transthyretin by Westermark, Per, Sletten, Knut, Johansson, Bjorn, Cornwell, Gibbons G.

“…The amyloid fibril in senile systemic amyloidosis (SSA), like that of familial amyloidotic polyneuropathy, is derived from transthyretin (TTR). SSA, however,…”
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Islet pathology of non-insulin-dependent diabetes mellitus (NIDDM) by Westermark, P

“…Islet amyloid polypeptide (IAPP) gives rise to islet amyloid fibrils in NIDDM. Islet amyloid tends to replace islet cells, especially beta-cells and may act as…”
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Co-localization of islet amyloid polypeptide and insulin in the B cell secretory granules of the human pancreatic islets by LUKINIUS, A, WILANDER, E, WESTERMARK, G. T, ENGSTROM, U, WESTERMARK, P

“…Islet amyloid polypeptide is a novel 37 amino-acid-residues polypeptide which has been isolated from amyloid deposits in an insulinoma, and in human and cat…”
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Diagnosing amyloidosis by Westermark, P

“…Diagnosis of amyloidosis still relies on tissue biopsy for microscopic examination. Biopsy from a symptom-giving organ may be used but more often an easily…”
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