Search Results - "Westerkamp, C."
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Dual hypothermic oxygenated machine perfusion in liver transplants donated after circulatory death
Published in British journal of surgery (01-06-2017)“…Background Experimental studies have suggested that end‐ischaemic dual hypothermic oxygenated machine perfusion (DHOPE) may restore hepatocellular energy…”
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Injury to peribiliary glands and vascular plexus before liver transplantation predicts formation of non-anastomotic biliary strictures
Published in Journal of hepatology (01-06-2014)“…Background & Aims The peribiliary glands of large bile ducts have been identified as a niche of progenitor cells that contribute to regeneration of biliary…”
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Oxygenated Hypothermic Machine Perfusion After Static Cold Storage Improves Hepatobiliary Function of Extended Criteria Donor Livers
Published in Transplantation (01-04-2016)“…BACKGROUNDThe mechanism through which oxygenated hypothermic machine perfusion (HMP) improves viability of human extended criteria donor (ECD) livers is not…”
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Ex vivo Normothermic Machine Perfusion and Viability Testing of Discarded Human Donor Livers
Published in American journal of transplantation (01-05-2013)“…In contrast to traditional static cold preservation of donor livers, normothermic machine perfusion may reduce preservation injury, improve graft viability and…”
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Normothermic machine perfusion reduces bile duct injury and improves biliary epithelial function in rat donor livers
Published in Liver transplantation (01-07-2016)“…Bile duct injury may occur during liver procurement and transplantation, especially in livers from donation after circulatory death (DCD) donors. Normothermic…”
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End‐ischemic machine perfusion reduces bile duct injury in donation after circulatory death rat donor livers independent of the machine perfusion temperature
Published in Liver transplantation (01-10-2015)“…A short period of oxygenated machine perfusion (MP) after static cold storage (SCS) may reduce biliary injury in donation after cardiac death (DCD) donor…”
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Oxygenated hypothermic machine perfusion after static cold storage improves endothelial function of extended criteria donor livers
Published in HPB (Oxford, England) (01-06-2017)“…Abstract Background Lack of oxygen and biomechanical stimulation during static cold storage (SCS) of donor livers compromises endothelial cell function. We…”
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MiR-324-5p inhibition after intrahippocampal kainic acid-induced status epilepticus does not prevent epileptogenesis in mice
Published in Frontiers in neurology (16-11-2023)“…Acquired epilepsies are caused by an initial brain insult that is followed by epileptogenesis and finally the development of spontaneous recurrent seizures…”
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Ricochet pollination in Senna (Fabaceae) - petals deflect pollen jets and promote division of labour among flower structures
Published in Plant biology (Stuttgart, Germany) (01-11-2017)“…Naturalists Fritz and Hermann Müller hypothesised that heteranthery often leads to a division of labour into 'feeding' and 'pollinating' stamens; the latter…”
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Metformin Preconditioning and Postconditioning to Reduce Ischemia Reperfusion Injury in an Isolated Ex Vivo Rat and Porcine Kidney Normothermic Machine Perfusion Model
Published in Clinical and translational science (01-01-2021)“…Metformin may act renoprotective prior to kidney transplantation by reducing ischemia‐reperfusion injury (IRI). This study examined whether metformin…”
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Diffuse reflectance spectroscopy accurately quantifies various degrees of liver steatosis in murine models of fatty liver disease
Published in Journal of translational medicine (21-09-2015)“…A real-time objective evaluation for the extent of liver steatosis during liver transplantation is currently not available. Diffuse reflectance spectroscopy…”
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Strict Selection Alone of Patients Undergoing Liver Transplantation for Hilar Cholangiocarcinoma Is Associated with Improved Survival
Published in PloS one (08-06-2016)“…Liver transplantation for hilar cholangiocarcinoma (hCCA) has regained attention since the Mayo Clinic reported their favorable results with the use of a…”
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Intraoperative frozen section analysis of the proximal bile ducts in hilar cholangiocarcinoma is of limited value
Published in Cancer medicine (Malden, MA) (01-07-2016)“…Frozen section analysis (FS) during cancer surgery is widely used to assess resection margins. However, in hilar cholangiocarcinoma (HCCA), FS may be less…”
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Increasing metformin concentrations and its excretion in both rat and porcine ex vivo normothermic kidney perfusion model
Published in BMJ open diabetes research & care (01-01-2020)“…IntroductionMetformin can accumulate and cause lactic acidosis in patients with renal insufficiency. Metformin is known to inhibit mitochondria, while renal…”
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Normothermic machine perfusion of donor livers without the need for human blood products
Published in Liver transplantation (01-04-2018)“…Normothermic machine perfusion (NMP) enables viability assessment of donor livers prior to transplantation. NMP is frequently performed by using human blood…”
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Keel flowers of the Polygalaceae and Fabaceae: a functional comparison
Published in Botanical journal of the Linnean Society (01-03-1999)“…Although the superficial similarity between Polygalaceae and Fabaceae flowers is well known, a comparison between their recently more precisely defined ‘keel…”
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High-Dose Methylphenidate and Carboxylesterase 1 Genetic Variability in Patients With Attention-Deficit/Hyperactivity Disorder: A Case Series
Published in Journal of clinical psychopharmacology (01-01-2024)“…Methylphenidate (MPH) is widely used to reduce symptoms of attention-deficit/hyperactivity disorder. Methylphenidate is metabolized by the carboxylesterase 1…”
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Metformin Preconditioning Improves Hepatobiliary Function and Reduces Injury in a Rat Model of Normothermic Machine Perfusion and Orthotopic Transplantation
Published in Transplantation (01-09-2020)“…BACKGROUND.Preconditioning of donor livers before organ retrieval may improve organ quality after transplantation. We investigated whether preconditioning with…”
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Delayed autonomous self-pollination in the colonizer Crotalaria micans (Fabaceae: Papilionoideae): structural and functional aspects
Published in Plant systematics and evolution (01-06-2003)“…We investigated the reproductive biology of Crotalaria micans, a colonizing species that occurs in disturbed sites. The flowers have two whorls of stamens with…”
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Activation of Fibrinolysis, But Not Coagulation, During End-Ischemic Ex Situ Normothermic Machine Perfusion of Human Donor Livers
Published in Transplantation (01-02-2017)“…BACKGROUNDEx situ normothermic machine perfusion (NMP) can be performed after traditional static cold preservation to assess graft function and viability…”
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