Search Results - "Westerhof, M."

Engineered Tools to Study Intercellular Communication by Yang, Benjamin A., Westerhof, Trisha M., Sabin, Kaitlyn, Merajver, Sofia D., Aguilar, Carlos A.

“…All multicellular organisms rely on intercellular communication networks to coordinate physiological functions. As members of a dynamic social network, each…”
Get full text

Effect of the Fast Pyrolysis Temperature on the Primary and Secondary Products of Lignin by Zhou, Shuai, Garcia-Perez, Manuel, Pecha, Brennan, Kersten, Sascha R. A, McDonald, Armando G, Westerhof, Roel J. M

“…This paper presents results on the primary pyrolysis products of organosolv lignin at temperatures between 360 and 700 °C. To study the primary products, a…”
Get full text

Heterogeneous and homogeneous reactions of pyrolysis vapors from pine wood by Hoekstra, Elly, Westerhof, Roel J. M., Brilman, Wim, Van Swaaij, Wim P.M., Kersten, Sascha R. A., Hogendoorn, Kees J. A., Windt, Michael

“…To maximize oil yields in the fast pyrolysis of biomass it is generally accepted that vapors need to be rapidly quenched. The influence of the heterogeneous…”
Get full text

Secondary Vapor Phase Reactions of Lignin-Derived Oligomers Obtained by Fast Pyrolysis of Pine Wood by Zhou, Shuai, Garcia-Perez, Manuel, Pecha, Brennan, McDonald, Armando G, Kersten, Sascha R. A, Westerhof, Roel J. M

“…In this paper, the effect of secondary reactions in vapor phase on the yield and composition of pyrolytic lignin (PL) oligomers was investigated. The Pine wood…”
Get full text

Dynamics of genetic rescue in inbred Drosophila melanogaster populations by Bijlsma, R, Westerhof, M. D. D, Roekx, L. P, Pen, I

“…Genetic rescue has been proposed as a management strategy to improve the fitness of genetically eroded populations by alleviating inbreeding depression. We…”
Get full text

Blood–Brain Barrier Remodeling in an Organ‐on‐a‐Chip Device Showing Dkk1 to be a Regulator of Early Metastasis by Westerhof, Trisha M., Yang, Benjamin A., Merill, Nathan M., Yates, Joel A., Altemus, Megan, Russell, Liam, Miller, Anna J., Bao, Liwei, Wu, Zhifen, Ulintz, Peter J., Aguilar, Carlos A., Morikawa, Aki, Castro, Maria G., Merajver, Sofia D., Oliver, Christopher R.

“…Brain metastases are the most lethal progression events, in part because the biological processes underpinning brain metastases are poorly understood. There is…”
Get full text

Blood–Brain Barrier Remodeling in an Organ‐on‐a‐Chip Device Showing Dkk1 to be a Regulator of Early Metastasis by Westerhof, Trisha M., Yang, Benjamin A., Merrill, Nathan M., Yates, Joel A., Altemus, Megan, Russell, Liam, Miller, Anna J., Bao, Liwei, Wu, Zhifen, Ulintz, Peter J., Aguilar, Carlos A., Morikawa, Aki, Castro, Maria G., Merajver, Sofia D., Oliver, Christopher R.

Get full text

The roles of resident, central and effector memory CD4 T‐cells in protective immunity following infection or vaccination by Gray, Joshua I., Westerhof, Lotus M., MacLeod, Megan K. L.

“…Summary Immunological memory provides rapid protection to pathogens previously encountered through infection or vaccination. CD4 T‐cells play a central role in…”
Get full text

Effect of Temperature in Fluidized Bed Fast Pyrolysis of Biomass: Oil Quality Assessment in Test Units by Westerhof, Roel J. M, Brilman, Derk W. F. (Wim), van Swaaij, Wim P. M, Kersten, Sacha R. A

“…Pine wood was pyrolyzed in a 1 kg/h fluidized bed fast pyrolysis reactor that allows a residence time of pine wood particles up to 25 min. The reactor…”
Get full text

Multifunctional cytokine production reveals functional superiority of memory CD4 T cells by Westerhof, Lotus M, McGuire, Kris, MacLellan, Lindsay, Flynn, Ashley, Gray, Joshua I, Thomas, Matthew, Goodyear, Carl S, MacLeod, Megan KL

“…T cell protective immunity is associated with multifunctional memory cells that produce several different cytokines. Currently, our understanding of when and…”
Get full text

Multifunctional cytokine production marks influenza A virus-specific CD4 T cells with high expression of survival molecules by Westerhof, Lotus M, Noonan, Jonathan, Hargrave, Kerrie E, Chimbayo, Elizabeth T, Cheng, Zhiling, Purnell, Thomas, Jackson, Mark R, Borcherding, Nicholas, MacLeod, Megan K L

“…Cytokine production by memory T cells is a key mechanism of T cell mediated protection. However, we have limited understanding of the persistence of cytokine…”
Get full text

A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche by Oliver, C Ryan, Altemus, Megan A, Westerhof, Trisha M, Cheriyan, Hannah, Cheng, Xu, Dziubinski, Michelle, Wu, Zhifen, Yates, Joel, Morikawa, Aki, Heth, Jason, Castro, Maria G, Leung, Brendan M, Takayama, Shuichi, Merajver, Sofia D

“…Brain metastases are the most lethal complication of advanced cancer; therefore, it is critical to identify when a tumor has the potential to metastasize to…”
Get more information

Stepwise Fast Pyrolysis of Pine Wood by Westerhof, Roel J. M, Brilman, D. Wim. F, Garcia-Perez, Manuel, Wang, Zhouhong, Oudenhoven, Stijn R. G, Kersten, Sascha R. A

“…This paper reports the yields and product composition obtained from the stepwise pyrolysis of pine wood in a fluidized bed reactor. The first step temperature…”
Get full text

Effect of Cellulose Crystallinity on Solid/Liquid Phase Reactions Responsible for the Formation of Carbonaceous Residues during Pyrolysis by Wang, Zhouhong, Pecha, Brennan, Westerhof, Roel J. M, Kersten, Sascha R. A, Li, Chun-Zhu, McDonald, Armando G, Garcia-Perez, Manuel

“…This study reports changes in solid phase composition when samples of Avicel cellulose (crystallinity: 60.5%) and ball-milled microcrystalline cellulose…”
Get full text

Effect of particle size on the composition of lignin derived oligomers obtained by fast pyrolysis of beech wood by Zhou, Shuai, Garcia-Perez, Manuel, Pecha, Brennan, McDonald, Armando G., Westerhof, Roel J.M.

“…•Pyrolysis of beech wood particles (0.3 and 14mm).•The yield of pyrolytic lignin decreased as particle size increased.•Two different pyrolysis regimes were…”
Get full text

Microfluidic filter device with nylon mesh membranes efficiently dissociates cell aggregates and digested tissue into single cells by Qiu, Xiaolong, Lombardo, Jeremy A, Westerhof, Trisha M, Pennell, Marissa, Ng, Anita, Alshetaiwi, Hamad, Luna, Brian M, Nelson, Edward L, Kessenbrock, Kai, Hui, Elliot E, Haun, Jered B

“…Tissues are increasingly being analyzed at the single cell level in order to characterize cellular diversity and identify rare cell types. Single cell analysis…”
Get more information

Quantifying the Brain Metastatic Tumor Micro-Environment using an Organ-On-A Chip 3D Model, Machine Learning, and Confocal Tomography by Oliver, C Ryan, Westerhof, Trisha M, Castro, Maria G, Merajver, Sofia D

“…Brain metastases are the most lethal cancer lesions; 10-30% of all cancers metastasize to the brain, with a median survival of only ~5-20 months, depending on…”
Get more information

Whole-blood sorting, enrichment and in situ immunolabeling of cellular subsets using acoustic microstreaming by Garg, Neha, Westerhof, Trisha M., Liu, Vick, Liu, Robin, Nelson, Edward L., Lee, Abraham P.

“…Analyzing undiluted whole human blood is a challenge due to its complex composition of hematopoietic cellular populations, nucleic acids, metabolites, and…”
Get full text

Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue by Qiu, Xiaolong, Huang, Jen-Huang, Westerhof, Trisha M., Lombardo, Jeremy A., Henrikson, Katrina M., Pennell, Marissa, Pourfard, Pedram P., Nelson, Edward L., Nath, Pulak, Haun, Jered B.

“…Maximizing the speed and efficiency at which single cells can be liberated from tissues would dramatically advance cell-based diagnostics and therapies…”
Get full text

A hybrid resistive pulse-optical detection platform for microfluidic experiments by Hinkle, Preston, Westerhof, Trisha M., Qiu, Yinghua, Mallin, David J., Wallace, Matthew L., Nelson, Edward L., Taborek, Peter, Siwy, Zuzanna S.

“…Resistive-pulse sensing is a label-free method for characterizing individual particles as they pass through ion-conducting channels or pores. During a…”
Get full text