Search Results - "Westerheide, S D"

Multifaceted roles of CCAR family proteins in the DNA damage response and cancer by Lugano, D., Barrett, L., Westerheide, S. D., Kee, Y.

“…The cell cycle apoptosis regulator (CCAR) family of proteins consists of two proteins, CCAR1 and CCAR2, that play a variety of roles in cellular physiology and…”
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The p65 (RelA) Subunit of NF-κB Interacts with the Histone Deacetylase (HDAC) Corepressors HDAC1 and HDAC2 To Negatively Regulate Gene Expression by Ashburner, Brian P., Westerheide, Sandy D., Baldwin, Albert S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Stress Inducibility of SIRT1 and Its Role in Cytoprotection and Cancer by Raynes, Rachel, Brunquell, Jessica, Westerheide, Sandy D

“…Cells must continuously respond to stressful insults via the upregulation of cytoprotective pathways. The longevity factor and deacetylase SIRT1 plays a…”
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The putative oncoprotein Bcl-3 induces cyclin D1 to stimulate G(1) transition by Westerheide, S D, Mayo, M W, Anest, V, Hanson, J L, Baldwin, Jr, A S

“…Bcl-3 is a distinctive member of the IkappaB family of NF-kappaB inhibitors because it can function to coactivate transcription. A potential involvement of…”
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PTEN Blocks Tumor Necrosis Factor-induced NF-κB-dependent Transcription by Inhibiting the Transactivation Potential of the p65 Subunit by Mayo, Marty W., Madrid, Lee V., Westerheide, Sandy D., Jones, David R., Yuan, Xiu-Juan, Baldwin, Albert S., Whang, Young E.

“…PTEN is a lipid phosphatase responsible for down-regulating the phosphoinositide 3-kinase product phosphatidylinositol 3,4,5-triphosphate. Phosphatidylinositol…”
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The MHC-specific enhanceosome and its role in MHC class I and beta(2)-microglobulin gene transactivation by Gobin, S J, van Zutphen, M, Westerheide, S D, Boss, J M, van den Elsen, P J

“…The promoter regions of MHC class I and beta(2)-microglobulin (beta(2)m) genes possess a regulatory module consisting of S, X, and Y boxes, which is shared by…”
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Activation of class II MHC genes requires both the X box region and the class II transactivator (CIITA) by Riley, J L, Westerheide, S D, Price, J A, Brown, J A, Boss, J M

“…CIITA, a gene that can complement a transcriptional mutation of the major histocompatibility complex (MHC) class II genes, was tested for its ability to…”
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Benchmarking Organic Micropollutants in Wastewater, Recycled Water and Drinking Water with In Vitro Bioassays by Escher, Beate I, Allinson, Mayumi, Altenburger, Rolf, Bain, Peter A, Balaguer, Patrick, Busch, Wibke, Crago, Jordan, Denslow, Nancy D, Dopp, Elke, Hilscherova, Klara, Humpage, Andrew R, Kumar, Anu, Grimaldi, Marina, Jayasinghe, B. Sumith, Jarosova, Barbora, Jia, Ai, Makarov, Sergei, Maruya, Keith A, Medvedev, Alex, Mehinto, Alvine C, Mendez, Jamie E, Poulsen, Anita, Prochazka, Erik, Richard, Jessica, Schifferli, Andrea, Schlenk, Daniel, Scholz, Stefan, Shiraishi, Fujio, Snyder, Shane, Su, Guanyong, Tang, Janet Y. M, Burg, Bart van der, Linden, Sander C. van der, Werner, Inge, Westerheide, Sandy D, Wong, Chris K. C, Yang, Min, Yeung, Bonnie H. Y, Zhang, Xiaowei, Leusch, Frederic D. L

“…Thousands of organic micropollutants and their transformation products occur in water. Although often present at low concentrations, individual compounds…”
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HLA-DMA and HLA-DMB gene expression functions through the conserved S-X- Y region by Westerheide, SD, Louis-Plence, P, Ping, D, He, XF, Boss, JM

“…The MHC class II homologous proteins HLA-DMA and HLA-DMB function in the loading of peptides onto class II molecules. Like the class II genes, the HLA-DM genes…”
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Orientation and positional mapping of the subunits of the multicomponent transcription factors RFX and X2BP to the major histocompatibility complex class II transcriptional enhancer by Westerheide, Sandy D., Boss, Jeremy M.

“…Major histocompatibility complex class II genes contain a common complex enhancer that allows for their coordinate regulation. The X box element of the…”
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Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5 by Brown, J A, He, X F, Westerheide, S D, Boss, J M

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Heat Shock Response Modulators as Therapeutic Tools for Diseases of Protein Conformation by Westerheide, Sandy D., Morimoto, Richard I.

“…The disruption of protein folding quality control results in the accumulation of a non-native protein species that can form oligomers, aggregates, and…”
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The Putative Oncoprotein Bcl-3 Induces Cyclin D1 To Stimulate G1 Transition by Westerheide, Sandy D., Mayo, Marty W., Anest, Vasiliki, Hanson, Julie L., Baldwin, Albert S.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Triptolide, an Inhibitor of the Human Heat Shock Response That Enhances Stress-induced Cell Death by Westerheide, Sandy D., Kawahara, Tiara L.A., Orton, Kai, Morimoto, Richard I.

“…Molecular chaperones, inducible by heat shock and a variety of other stresses, have critical roles in protein homeostasis, balancing cell stress with…”
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Celastrols as Inducers of the Heat Shock Response and Cytoprotection[boxs] by Westerheide, Sandy D., Bosman, Joshua D., Mbadugha, Bessie N.A., Kawahara, Tiara L.A., Matsumoto, Gen, Kim, Soojin, Gu, Wenxin, Devlin, John P., Silverman, Richard B., Morimoto, Richard I.

“…Alterations in protein folding and the regulation of conformational states have become increasingly important to the functionality of key molecules in…”
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The MHC-Specific Enhanceosome and Its Role in MHC Class I and β2-Microglobulin Gene Transactivation by Gobin, Sam J. P., van Zutphen, Marlijn, Westerheide, Sandy D., Boss, Jeremy M., van den Elsen, Peter J.

“…Abstract The promoter regions of MHC class I and β2-microglobulin (β2m) genes posses a regulatory module consisting of S, X, and Y boxes, which is shared by…”
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The Putative Oncoprotein Bcl-3 Induces Cyclin D1 To Stimulate G sub(1) Transition by Westerheide, S D, Mayo, M W, Anest, V, Hanson, J L, Baldwin Jr., AS

“…Bcl-3 is a distinctive member of the I Kappa B family of NF- Kappa B inhibitors because it can function to coactivate transcription. A potential involvement of…”
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The p65 (RelA) subunit of NF-kappaB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression by Ashburner, B P, Westerheide, S D, Baldwin, Jr, A S

“…Regulation of NF-kappaB transactivation function is controlled at several levels, including interactions with coactivator proteins. Here we show that the…”
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The MHC-Specific Enhanceosome and Its Role in MHC Class I and beta sub(2)- Microglobulin Gene Transactivation by Gobin, SJP, van Zutphen, M, Westerheide, S D, Boss, J M, van den Elsen, PJ

“…The promoter regions of MHC class I and beta sub(2)-microglobulin ( beta sub(2)m) genes posses a regulatory module consisting of S, X, and Y boxes, which is…”
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Tumor Necrosis Factor alpha -induced Phosphorylation of RelA/p65 on Ser super(529) Is Controlled by Casein Kinase II by Wang, D, Westerheide, S D, Hanson, J L, Baldwin Jr., AS

“…Nuclear factor Kappa B (NF- Kappa B)/Rel transcription factors are key regulators of a variety of genes involved in immune and inflammatory responses, growth,…”
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