Search Results - "Westerberg, L. S."

Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells by Madapura, H S, Nagy, N, Ujvari, D, Kallas, T, Kröhnke, M C L, Amu, S, Björkholm, M, Stenke, L, Mandal, P K, McMurray, J S, Keszei, M, Westerberg, L S, Cheng, H, Xue, F, Klein, G, Klein, E, Salamon, D

“…B-cell CLL/lymphoma 6 (BCL6) exerts oncogenic effects in several human hematopoietic malignancies including chronic myeloid leukemia (CML), where BCL6…”
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Characterization of clonal evolution in pediatric lymphoma using single‐cell transcriptomics by D'aulerio, R., Yong, T., Oertlin, C., Record, J. A., Kwiecinska, A., Baecklund, F., Westerberg, L. S.

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Breakdown of T cell tolerance and autoimmunity in primary immunodeficiency—lessons learned from monogenic disorders in mice and men by Westerberg, Lisa S, Klein, Christoph, Snapper, Scott B

“…A key feature of the immune system is the capacity to monitor and control infections from non-self pathogens while maintaining tolerance to self-antigens…”
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The Small Rho GTPases Rac1 and Rac2 Are Important for T-Cell Independent Antigen Responses and for Suppressing Switching to IgG2b in Mice by Gerasimčik, Natalija, He, Minghui, Dahlberg, Carin I M, Kuznetsov, Nikolai V, Severinson, Eva, Westerberg, Lisa S

“…The Rho GTPases Cdc42, Rac1, and Rac2 coordinate receptor signaling to cell adhesion, migration, and proliferation. Deletion of Rac1 and Rac2 early during B…”
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17th International Conference on Malignant Lymphoma, Palazzo dei Congressi, Lugano, Switzerland, 13 - 17 June, 2023 by D'aulerio, R, Yong, T, Oertlin, C, Record, J A, Kwiecinska, A, Baecklund, F, Westerberg, L S

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Retraction: Akt2 Regulates the Differentiation and Function of NKT17 Cells via FoxO-1-ICOS Axis

“…[This retracts the article DOI: 10.3389/fimmu.2018.01940.]…”
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Interferon [gamma] is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells by Madapura, H S, Nagy, N, Ujvari, D, Kallas, T, Kröhnke, M C L, Amu, S, Björkholm, M, Stenke, L, Mandal, P K, McMurray, J S, Keszei, M, Westerberg, L S, Cheng, H, Xue, F, Klein, G, Klein, E, Salamon, D

“…B-cell CLL/lymphoma 6 (BCL6) exerts oncogenic effects in several human hematopoietic malignancies including chronic myeloid leukemia (CML), where BCL6…”
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CD73 immune checkpoint defines regulatory NK cells within the tumor microenvironment by Neo, Shi Yong, Yang, Ying, Record, Julien, Ma, Ran, Chen, Xinsong, Chen, Ziqing, Tobin, Nicholas P, Blake, Emily, Seitz, Christina, Thomas, Ron, Wagner, Arnika Kathleen, Andersson, John, de Boniface, Jana, Bergh, Jonas, Murray, Shannon, Alici, Evren, Childs, Richard, Johansson, Martin, Westerberg, Lisa S, Haglund, Felix, Hartman, Johan, Lundqvist, Andreas

“…High levels of ecto-5'-nucleotidase (CD73) have been implicated in immune suppression and tumor progression, and have also been observed in cancer patients who…”
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Pharmacologic Activation of p53 Triggers Viral Mimicry Response Thereby Abolishing Tumor Immune Evasion and Promoting Antitumor Immunity by Zhou, Xiaolei, Singh, Madhurendra, Sanz Santos, Gema, Guerlavais, Vincent, Carvajal, Luis A, Aivado, Manuel, Zhan, Yue, Oliveira, Mariana M S, Westerberg, Lisa S, Annis, D Allen, Johnsen, John Inge, Selivanova, Galina

“…The repression of repetitive elements is an important facet of p53's function as a guardian of the genome. Paradoxically, we found that p53 activated by MDM2…”
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T cell responses at diagnosis of amyotrophic lateral sclerosis predict disease progression by Yazdani, Solmaz, Seitz, Christina, Cui, Can, Lovik, Anikó, Pan, Lu, Piehl, Fredrik, Pawitan, Yudi, Kläppe, Ulf, Press, Rayomand, Samuelsson, Kristin, Yin, Li, Vu, Trung Nghia, Joly, Anne-Laure, Westerberg, Lisa S., Evertsson, Björn, Ingre, Caroline, Andersson, John, Fang, Fang

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease, involving neuroinflammation and T cell infiltration in the central nervous system…”
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Alternative Splicing of FOXP3 Controls Regulatory T Cell Effector Functions and Is Associated With Human Atherosclerotic Plaque Stability by Joly, Anne-Laure, Seitz, Christina, Liu, Sang, Kuznetsov, Nikolai V, Gertow, Karl, Westerberg, Lisa S, Paulsson-Berne, Gabrielle, Hansson, Göran K, Andersson, John

“…RATIONALE:Regulatory T (Treg) cells suppress immune responses and have been shown to attenuate atherosclerosis. The Treg cell lineage-specification factor…”
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Cytoskeletal regulation of dendritic cells: An intricate balance between migration and presentation for tumor therapy by Oliveira, Mariana M.S., Westerberg, Lisa S.

“…Dendritic cells (DCs) are the main players in many approaches for cancer therapy. The idea with DC tumor therapy is to promote activation of tumor infiltrating…”
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Understanding immunoactinopathies: A decade of research on WAS gene defects by Vieira, Rhaissa Calixto, Pinho, Lia Goncalves, Westerberg, Lisa S.

“…Immunoactinopathies caused by mutations in actin‐related proteins are a growing group of inborn errors of immunity (IEI). Immunoactinopathies are caused by a…”
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CD36 and LC3B initiated autophagy in B cells regulates the humoral immune response by He, Chenfei, Wang, Shan, Zhou, Chikai, He, Minghui, Wang, Jin, Ladds, Marcus, Lianoudaki, Danai, Sedimbi, Saikiran K., Lane, David P., Westerberg, Lisa S., Li, Shuijie, Karlsson, Mikael C.I.

“…Scavenger receptors are pattern recognition receptors that recognize both foreign and self-ligands, and initiate different mechanisms of cellular activation,…”
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Mutant p53 gain of function mediates cancer immune escape that is counteracted by APR-246 by Zhou, Xiaolei, Santos, Gema Sanz, Zhan, Yue, Oliveira, Mariana M. S., Rezaei, Shiva, Singh, Madhurendra, Peuget, Sylvain, Westerberg, Lisa S., Johnsen, John Inge, Selivanova, Galina

“…Background p53 mutants contribute to the chronic inflammatory tumour microenvironment (TME). In this study, we address the mechanism of how p53 mutants lead to…”
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Increased cross-presentation by dendritic cells and enhanced anti-tumour therapy using the Arp2/3 inhibitor CK666 by Oliveira, Mariana M. S., D’Aulerio, Roberta, Yong, Tracer, He, Minghui, Baptista, Marisa A. P., Nylén, Susanne, Westerberg, Lisa S.

“…Background Dendritic cell (DC) vaccines for cancer therapy offer the possibility to let the patient’s own immune system kill cancer cells. However, DC vaccines…”
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H1N1 vaccination in Sjögren's syndrome triggers polyclonal B cell activation and promotes autoantibody production by Brauner, Susanna, Folkersen, Lasse, Kvarnström, Marika, Meisgen, Sabrina, Petersen, Sven, Franzén-Malmros, Michaela, Mofors, Johannes, Brokstad, Karl A, Klareskog, Lars, Jonsson, Roland, Westerberg, Lisa S, Trollmo, Christina, Malmström, Vivianne, Ambrosi, Aurelie, Kuchroo, Vijay K, Nordmark, Gunnel, Wahren-Herlenius, Marie

“…Vaccination of patients with rheumatic disease has been reported to result in lower antibody titres than in healthy individuals. However, studies primarily…”
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Controlled WASp activity regulates the proliferative response for Treg cell differentiation in the thymus by Vasconcelos‐Fontes, Larissa, Vieira, Rhaissa C., He, Minghui, Ferreira‐Reis, Rafaella, Jurberg, Arnon Dias, Arêas Mendes‐da‐Cruz, Daniella, Andersson, John, Cotta‐de‐Almeida, Vinicius, Westerberg, Lisa S.

“…The Wiskott–Aldrich syndrome protein (WASp) regulates actin cytoskeletal dynamics and function of hematopoietic cells. Mutations in the WAS gene lead to two…”
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The interaction between iNKT cells and B cells by Zhu, Tong, Wang, Rongli, Miller, Heather, Westerberg, Lisa S., Yang, Lu, Guan, Fei, Lee, Pamela, Gong, Quan, Chen, Yan, Liu, Chaohong

“…Invariant natural killer T cells (iNKTs) bridge the innate immunity with the adaptive immunity and their interaction with B cells has been extensively studied…”
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Immune Dysregulation in IgG4-Related Disease by Liu, Jiachen, Yin, Wei, Westerberg, Lisa S., Lee, Pamela, Gong, Quan, Chen, Yan, Dong, Lingli, Liu, Chaohong

“…Immunoglobin G 4 -related disease (IgG 4 -RD) is one of the newly discovered autoimmune diseases characterized by elevated serum IgG 4 concentrations and…”
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