Search Results - "Westen, D"
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Apathy and anxiety are early markers of Alzheimer's disease
Published in Neurobiology of aging (01-01-2020)“…In this study, we investigated associations between neuropsychiatric symptoms (i.e., apathy, anxiety, and depression) and cerebral atrophy, white matter…”
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Plasma markers predict changes in amyloid, tau, atrophy and cognition in non-demented subjects
Published in Brain (London, England : 1878) (22-10-2021)“…It is currently unclear whether plasma biomarkers can be used as independent prognostic tools to predict changes associated with early Alzheimer's disease. In…”
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Glioma Grade Discrimination with MR Diffusion Kurtosis Imaging: A Meta-Analysis of Diagnostic Accuracy
Published in Radiology (01-04-2018)“…Purpose To assess the diagnostic test accuracy and sources of heterogeneity for the discriminative potential of diffusion kurtosis imaging (DKI) to…”
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Brain myoinositol as a potential marker of amyloid-related pathology: A longitudinal study
Published in Neurology (29-01-2019)“…OBJECTIVETo investigate the association between longitudinal changes in proton magnetic resonance spectroscopy (MRS) metabolites and amyloid pathology in…”
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5
Arterial Spin-Labeling in Children with Brain Tumor: A Meta-Analysis
Published in American journal of neuroradiology : AJNR (01-08-2018)“…The value of arterial spin-labeling in a pediatric population has not been assessed in a meta-analysis. Our aim was to assess the diagnostic accuracy of…”
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18F-Flortaucipir in TDP-43 associated frontotemporal dementia
Published in Scientific reports (15-04-2019)“…Retention of 18 F-Flortaucipir is reportedly increased in the semantic variant of primary progressive aphasia (svPPA), which is dominated by TDP-43 pathology…”
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Longitudinal degeneration of the basal forebrain predicts subsequent dementia in Parkinson's disease
Published in Neurobiology of disease (01-06-2020)“…Cholinergic dysfunction plays a prominent role in cognitive impairment in Parkinson's disease (PD). The aim of this study was to assess the relationship of…”
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Plasma neurofilament light protein correlates with diffusion tensor imaging metrics in frontotemporal dementia
Published in PloS one (27-10-2020)“…Neurofilaments are structural components of neurons and are particularly abundant in highly myelinated axons. The levels of neurofilament light chain (NfL) in…”
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MRI of the Swallow Tail Sign: A Useful Marker in the Diagnosis of Lewy Body Dementia?
Published in American journal of neuroradiology : AJNR (01-09-2017)“…There are, to date, no MR imaging diagnostic markers for Lewy body dementia. Nigrosome 1, containing dopaminergic cells, in the substantia nigra pars compacta…”
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White matter lesions and brain atrophy in systemic lupus erythematosus patients: correlation to cognitive dysfunction in a cohort of systemic lupus erythematosus patients using different definition models for neuropsychiatric systemic lupus erythematosus
Published in Lupus (01-06-2018)“…Aim The aim of this study was to evaluate the extent of white matter lesions, atrophy of the hippocampus and corpus callosum, and their correlation with…”
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Fixel-Based Analysis Reveals Tau-Related White Matter Changes in Early Stages of Alzheimer's Disease
Published in The Journal of neuroscience (01-05-2024)“…Several studies have shown white matter (WM) abnormalities in Alzheimer's disease (AD) using diffusion tensor imaging (DTI). Nonetheless, robust…”
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CSF Aβ42/Aβ40 and Aβ42/Aβ38 ratios: better diagnostic markers of Alzheimer disease
Published in Annals of clinical and translational neurology (2016)“…Objective The diagnostic accuracy of cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD) must be improved before widespread clinical use. This…”
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13
Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer's disease
Published in Alzheimer's & dementia (01-02-2020)“…Differential patterns of brain atrophy on structural magnetic resonance imaging (MRI) revealed four reproducible subtypes of Alzheimer's disease (AD): (1)…”
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CT‐based volumetric measures obtained through deep learning: Association with biomarkers of neurodegeneration
Published in Alzheimer's & dementia (01-01-2024)“…INTRODUCTION Cranial computed tomography (CT) is an affordable and widely available imaging modality that is used to assess structural abnormalities, but not…”
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Abnormal Structural Brain Connectome in Individuals with Preclinical Alzheimer's Disease
Published in Cerebral cortex (New York, N.Y. 1991) (01-10-2018)“…Abstract Alzheimer's disease has a long preclinical phase during which amyloid pathology and neurodegeneration accumulate in the brain without producing overt…”
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Imaging biomarkers of dementia: recommended visual rating scales with teaching cases
Published in Insights into imaging (01-02-2017)“…The diagnostic work up of dementia may benefit from structured reporting of CT and/or MRI and the use of standardised visual rating scales. We advocate a more…”
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Prenatal gyrification pattern affects age at onset in frontotemporal dementia
Published in Cerebral cortex (New York, N.Y. 1991) (04-09-2022)“…Abstract The paracingulate sulcus is a tertiary sulcus formed during the third trimester. In healthy individuals paracingulate sulcation is more prevalent in…”
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Arterial spin labeling MR imaging for differentiation between high- and low-grade glioma-a meta-analysis
Published in Neuro-oncology (Charlottesville, Va.) (09-10-2018)“…Arterial spin labeling is an MR imaging technique that measures cerebral blood flow (CBF) non-invasively. The aim of the study is to assess the diagnostic…”
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Deep learning from MRI-derived labels enables automatic brain tissue classification on human brain CT
Published in NeuroImage (Orlando, Fla.) (01-12-2021)“…•We developed a method for automatic brain tissue classification on CT images.•Used appropriately, the method may obviate the clinical need for MRI to quantify…”
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Amyloid Network Topology Characterizes the Progression of Alzheimer's Disease During the Predementia Stages
Published in Cerebral cortex (New York, N.Y. 1991) (01-01-2018)“…Abstract There is increasing evidence showing that the accumulation of the amyloid-β (Aβ) peptide into extracellular plaques is a central event in Alzheimer's…”
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