Search Results - "Westbrook, Carol A"

Challenges to Forming Physician Unions by Westbrook, Carol A

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Molecular characterization and expression of the gene encoding human erythroid-potentiating activity by Gasson, Judith C, Golde, David W, Kaufman, Susan E, Westbrook, Carol A, Hewick, Rodney M, Kaufman, Randal J, Wong, Gordon G, Temple, Patricia A, Leary, Ann C, Brown, Eugene L, Orr, Elizabeth C, Clark, Steven C

“…Erythropoietin is the primary physiological regulator of erythropoiesis; however, in vitro studies have identified another class of mediators which appear to…”
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A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31 by ZHENBO HU, GOMES, Ignatius, WESTBROOK, Carol A, HORRIGAN, Stephen K, KRAVARUSIC, Jelena, MAR, Brenton, ARBIEVA, Zarema, CHYNA, Brent, FULTON, Noreen, EDASSERY, Seby, RAZA, Azra

“…Interstitial deletion or loss of chromosome 5, del(5q) or -5, is a frequent finding in myeloid leukemias and myelodysplasias, suggesting the presence of a…”
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Membrane-associated and secreted genes in breast cancer by STITZIEL, Nathan O, MAR, Brenton G, JIE LIANG, WESTBROOK, Carol A

“…The identification of membrane-associated and secreted genes that are differentially expressed is a useful step in defining new targets for the diagnosis and…”
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Challenges to Forming Physician Unions/Reply by Westbrook, Carol A, Richman, Barak D, Schulman, Kevin A

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Lineage specific treatment of adult patients with acute lymphoblastic leukemia in first remission with anti-B4-blocked ricin or high-dose cytarabine: Cancer and leukemia group B study 9311 by SZATROWSKI, Ted P, DODGE, Richard K, STONE, Richard M, BLOOMFIELD, Clara D, SCHIFFER, Charles A, LARSON, Richard A, REYNOLDS, Carol, WESTBROOK, Carol A, FRANKEL, Stanley R, SKLAR, Jeffrey, STEWART, Carleton C, HURD, David D, KOLITZ, Jonathan E, VELEZ-GARCIA, Enrique

“…Anti-B4-blocked ricin is an immunotoxin comprised of an anti-CD19 murine monoclonal antibody (B4) conjugated to blocked ricin, which has cytotoxic activity in…”
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Novel transcription factors in human CD34 antigen–positive hematopoietic cells by Gomes, Ignatius, Sharma, Tiffany T., Edassery, Seby, Fulton, Noreen, Mar, Brenton G., Westbrook, Carol A.

“…Transcription factors (TFs) and the regulatory proteins that control them play key roles in hematopoiesis, controlling basic processes of cell growth and…”
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Highly abundant genes in the transcriptosome of human and baboon CD34 antigen-positive bone marrow cells by Gomes, Ignatius, Sharma, Tiffany T., Mahmud, Nadim, Kapp, Jeffrey D., Edassery, Seby, Fulton, Noreen, Liang, Jie, Hoffman, Ronald, Westbrook, Carol A.

“…Nonhuman primates are useful large animal model systems for the in vivo study of hematopoietic stem cell biology. To better understand the degree of similarity…”
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High-resolution physical map and transcript identification of a prostate cancer deletion interval on 8p22 by Arbieva, Z H, Banerjee, K, Kim, S Y, Edassery, S L, Maniatis, V S, Horrigan, S K, Westbrook, C A

“…A genomic interval of approximately 1-1.5 Mb centered at the MSR marker on 8p22 has emerged as a possible site for a tumor suppressor gene, based on high rates…”
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Deletion mapping reveals two regions of chromosome 8 allele loss in colorectal carcinomas by Yaremko, M L, Wasylyshyn, M L, Paulus, K L, Michelassi, F, Westbrook, C A

“…Colorectal carcinogenesis is associated with the accumulation of genetic changes involving both dominant oncogenes and tumor suppressor genes. Although at…”
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Evidence for the Involvement of GM-CSF and FMS in the Deletion (5q) in Myeloid Disorders by Le Beau, Michelle M., Westbrook, Carol A., Diaz, Manuel O., Larson, Richard A., Rowley, Janet D., Gasson, Judith C., Golde, David W., Sherr, Charles J.

“…By in situ chromosomal hybridization, the GM-CSF and FMS genes were localized to human chromosome 5 at bands q23 to q31, and at band 5q33, respectively. These…”
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Delineation of a minimal interval and identification of 9 candidates for a tumor suppressor gene in malignant myeloid disorders on 5q31 by Horrigan, Stephen K., Arbieva, Zarema H., Xie, Hong Yan, Kravarusic, Jelena, Fulton, Noreen C., Naik, Haley, Le, Tiffany T., Westbrook, Carol A.

“…Interstitial deletion or loss of chromosome 5 is frequent in malignant myeloid disorders, including myelodysplasia (MDS) and acute myeloid leukemia (AML),…”
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Gene therapy of the gut: introduction of the APC tumor-suppressor gene for cancer prevention or treatment by Westbrook, Carol A., Arenas, Richard B.

“…Liposomal delivery of gene therapy to the colonic epithelium has been evaluated in a rodent model. The use of β-galactosidase as a reporter gene demonstrated…”
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Evidence for two distinct c- src loci on human chromosomes 1 and 20 by Le Beau, Michelle M, Westbrook, Carol A, Diaz, Manuel O, Rowley, Janet D

“…A number of proto-oncogenes have recently been localized to the chromosomal segments that are the breakpoints in the specific rearrangements noted in human…”
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Myotilin is mutated in limb girdle muscular dystrophy 1A by HAUSER, M. A, HORRIGAN, S. K, STAJICH, J. M, GASKELL, P. C, GILBERT, J. R, VANCE, J. M, PERICAK-VANCE, M. A, CARPEN, O, WESTBROOK, C. A, SPEER, M. C, SALMIKANGAS, P, TORIAN, U. M, VILES, K. D, DANCEL, R, TIM, R. W, TAIVAINEN, A, BARTOLONI, L, GILCHRIST, J. M

“…We have identified a mutation in the myotilin gene in a large North American family of German descent expressing an autosomal dominant form of limb girdle…”
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Exclusion of identified LGMD1 loci from four dominant limb-girdle muscular dystrophy families by Speer, M C, Vance, J M, Lennon-Graham, F, Stajich, J M, Viles, K D, Gilchrist, J M, Nigro, V, McMichael, R, Chutkow, J G, Bartoloni, L, Horrigan, S K, Westbrook, C A, Pericak-Vance, M A

“…The limb-girdle muscular dystrophies are a clinically and genetically heterogeneous group of disorders. Recent linkage analyses and positional cloning studies…”
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A Five-Drug Remission Induction Regimen With Intensive Consolidation for Adults With Acute Lymphoblastic Leukemia: Cancer and Leukemia Group B Study 8811 by Larson, Richard A., Dodge, Richard K., Burns, C.Patrick, Lee, Edward J., Stone, Richard M., Schulman, Philip, Duggan, David, Davey, Frederick R., Sobol, Robert E., Frankel, Stanley R., Hooberman, Arthur L., Westbrook, Carol A., Arthur, Diane C., George, Stephen L., Bloomfield, Clara D., Schiffer, Charles A.

“…The goal of this phase II multicenter clinical trial was to evaluate a new intensive chemotherapy program for adults with untreated acute lymphoblastic…”
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Delineation of a minimal interval and identification of 9 candidates for a tumor suppressor gene in malignant myeloid disorders on 5q31 by Horrigan, Stephen K., Arbieva, Zarema H., Xie, Hong Yan, Kravarusic, Jelena, Fulton, Noreen C., Naik, Haley, Le, Tiffany T., Westbrook, Carol A.

“…Interstitial deletion or loss of chromosome 5 is frequent in malignant myeloid disorders, including myelodysplasia (MDS) and acute myeloid leukemia (AML),…”
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Translocation of the p53 gene in t(15;17) in acute promyelocytic leukaemia by Le Beau, Michelle M, Westbrook, Carol A, Diaz, Manuel O, Rowley, Janet D, Oren, Moshe

“…Recent studies have demonstrated that the cellular tumour antigen p53 (ref. 1) can complement activated ras genes in the transformation of rat fibroblasts,…”
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Cytogenetic and Molecular Delineation of the Smallest Commonly Deleted Region of Chromosome 5 in Malignant Myeloid Diseases by Le Beau, Michelle M., Espinosa, Rafael, Neuman, Wilma L., Stock, Wendy, Roulston, Diane, Larson, Richard A., Keinanen, Mauri, Westbrook, Carol A.

“…Loss of a whole chromosome 5 or a deletion of its long arm (5q) is a recurring abnormality in malignant myeloid neoplasms. To determine the location of genes…”
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