Search Results - "West, Zoe"
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Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing
Published in International journal of molecular sciences (17-07-2017)“…Macrophages and inflammation play a beneficial role during wound repair with macrophages regulating a wide range of processes, such as removal of dead cells,…”
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Invasion by activated macrophages requires delivery of nascent membrane‐type‐1 matrix metalloproteinase through late endosomes/lysosomes to the cell surface
Published in Traffic (Copenhagen, Denmark) (01-09-2019)“…Macrophage migration into injured or infected tissue is a key aspect in the pathophysiology of many diseases where inflammation is a driving factor…”
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Development and use of biomaterials as wound healing therapies
Published in Burns and trauma (2019)“…There is a vast number of treatments on the market for the management of wounds and burns, representing a multi-billion dollar industry worldwide. These…”
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The trans‐SNARE complex VAMP4/Stx6/Stx7/Vti1b is a key regulator of Golgi to late endosome MT1‐MMP transport in macrophages
Published in Traffic (Copenhagen, Denmark) (01-11-2021)“…The activity of the matrix metalloproteinase (MMP) MT1‐MMP is strictly regulated by expression and cellular location. In macrophages LPS activation leads to…”
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Whole-brain spatial transcriptional analysis at cellular resolution
Published in Science (American Association for the Advancement of Science) (22-11-2024)“…Editor’s summarySpatial transcriptomics is a powerful method that measures the localization of mRNA molecules. When applying this approach in tissues, analysis…”
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Disrupted Cacna1c gene expression perturbs spontaneous Ca2+ activity causing abnormal brain development and increased anxiety
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-2022)“…The L-type voltage-gated Ca2+ channel gene CACNA1C is a risk gene for various psychiatric conditions, including schizophrenia and bipolar disorder. However,…”
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Disrupted Cacna1c gene expression perturbs spontaneous Ca 2+ activity causing abnormal brain development and increased anxiety
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-2022)“…The L-type voltage-gated Ca channel gene is a risk gene for various psychiatric conditions, including schizophrenia and bipolar disorder. However, the cellular…”
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Relationships between maternal body mass index and child cognitive outcomes at 3 years of age are buffered by specific early environments in a prospective Canadian birth cohort
Published in Journal of developmental origins of health and disease (01-02-2023)“…Fetal and child development are shaped by early life exposures, including maternal health states, nutrition and educational and home environments. We aimed to…”
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Study protocol for Attachment & Child Health (ATTACHTM) program: promoting vulnerable Children’s health at scale
Published in BMC pediatrics (19-08-2022)“…Background Children's exposure to toxic stress (e.g., parental depression, violence, poverty) predicts developmental and physical health problems resulting in…”
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10
Three-dimensional imaging of upper tract urothelial carcinoma improves diagnostic yield and accuracy
Published in JCI insight (22-07-2024)“…Upper tract urothelial carcinoma (UTUC) is a rare form of urothelial cancer with a high incidence of recurrence and a low survival rate. Almost two-thirds of…”
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Healing into Power: An Approach for Confronting Workplace Sexual Violence
Published in New labor forum (01-05-2021)“…Since its emergence in the early 1990s, the Justice for Janitors campaign has held a place of prominence in the annals of the U.S. labor movement, helping to…”
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Negotiating Justice and Possibility : Alternative Labor Organizing in New York
Published 01-01-2017“…Amid broad consensus about the urgency of transforming and revitalizing the US labor movement, alternative labor organizations such as worker centers have…”
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