Search Results - "West, Rachel C"
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Dynamics of trophoblast differentiation in peri-implantation-stage human embryos
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2019)“…Single-cell RNA sequencing of cells from cultured human blastocysts has enabled us to define the transcriptomic landscape of placental trophoblast (TB) that…”
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Shifting perspectives from "oncogenic" to oncofetal proteins; how these factors drive placental development
Published in Reproductive biology and endocrinology (19-10-2018)“…Early human placental development strongly resembles carcinogenesis in otherwise healthy tissues. The progenitor cells of the placenta, the cytotrophoblast,…”
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Androgen receptor and histone lysine demethylases in ovine placenta
Published in PloS one (12-02-2015)“…Sex steroid hormones regulate developmental programming in many tissues, including programming gene expression during prenatal development. While estradiol is…”
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Induced pluripotency in chicken embryonic fibroblast results in a germ cell fate
Published in Stem cells and development (01-08-2014)“…Germ cells (GCs) are critically important as the vehicle that passes genetic information from one generation to the next. Correct development of these cells is…”
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Sex differences in innate and adaptive immunity impact fetal, placental, and maternal health
Published in Biology of reproduction (12-09-2023)“…The differences between males and females begin shortly after birth, continue throughout prenatal development, and eventually extend into childhood and adult…”
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Beyond fusion: A novel role for ERVW-1 in trophoblast proliferation and type I interferon receptor expression
Published in Placenta (Eastbourne) (01-08-2022)“…Throughout human pregnancy there is a delicate balance between the maintenance of a proliferative, trophoblast stem cell pool (TSC) and the differentiation…”
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Transcriptome comparisons of trophoblasts from regenerative cell models with peri-implantation human embryos
Published in Biology of reproduction (11-11-2024)“…Mechanisms controlling trophoblast proliferation and differentiation during embryo implantation are poorly understood. Human trophoblast stem cells (TSC) and…”
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Maternal physiology and blastocyst morphology are correlated with an inherent difference in peri-implantation human embryo development
Published in Fertility and sterility (01-06-2022)“…To determine what patient and embryo characteristics are correlated with the developmental potential of the peri-implantation embryo. Retrospective study…”
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LIN28B regulates androgen receptor in human trophoblast cells through Let‐7c
Published in Molecular reproduction and development (01-09-2019)“…LIN28B is an RNA‐binding protein necessary for maintaining pluripotency in stem cells and plays an important role in trophoblast cell differentiation. LIN28B…”
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BRCA1 regulates HMGA2 levels in the Swan71 trophoblast cell line
Published in Molecular reproduction and development (01-11-2019)“…During early placental development, tumor suppressors and oncogenes work synergistically to regulate cell proliferation and differentiation in a restrained…”
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Absence of SARS-CoV-2 (COVID-19 virus) within the IVF laboratory using strict patient screening and safety criteria
Published in Reproductive biomedicine online (01-06-2021)“…Is there a risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral exposure and potential cross-contamination from follicular fluid, culture…”
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Androgen Receptor and Histone Lysine Demethylases in Ovine Placenta: e0117472
Published in PloS one (12-02-2015)“…Sex steroid hormones regulate developmental programming in many tissues, including programming gene expression during prenatal development. While estradiol is…”
Get full text
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Development and Evaluation of the Lifestyle History Questionnaire (LHQ) for People Entering Treatment for Substance Addictions
Published in The American journal of occupational therapy (01-05-2015)“…We developed and investigated the psychometric properties of the Lifestyle History Questionnaire (LHQ), a self-report instrument designed to measure the extent…”
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SENSITIVE TOXICITY TESTING OF ART DISPOSABLES USING HUMAN PLURIPOTENT STEM CELLS
Published in Fertility and sterility (01-09-2020)Get full text
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THE HUMAN ENDOGENOUS RETROVIRUS ERVW-1 REGULATES TROPHOBLAST STEM CELL PROLIFERATION
Published in Fertility and sterility (01-09-2020)Get full text
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IN VITRO PERI-IMPLANTATION DEVELOPMENT OF GOOD QUALITY HUMAN EMBRYOS IS AFFECTED BY BLASTOCYST MORPHOLOGICAL GRADE AND MATERNAL AGE
Published in Fertility and sterility (01-09-2020)Get full text
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ABSENCE OF COVID-19 VIRUS WITHIN AN ACTIVE IVF LABORATORY USING STRICT PATIENT SCREENING AND SAFETY CRITERIA
Published in Fertility and sterility (01-09-2020)Get full text
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Dynamics of trophoblast differentiation in periimplantation–stage human embryos
Published in Proceedings of the National Academy of Sciences - PNAS (05-11-2019)“…Single-cell RNA sequencing of cells from cultured human blastocysts has enabled us to define the transcriptomic landscape of placental trophoblast (TB) that…”
Get full text
Journal Article