Search Results - "West, Neva"

Early Stages of Alzheimer's Disease: Evolving the Care Team for Optimal Patient Management by Galvin, James E, Aisen, Paul, Langbaum, Jessica B, Rodriguez, Eric, Sabbagh, Marwan, Stefanacci, Richard, Stern, Robert A, Vassey, Elizabeth A, de Wilde, Arno, West, Neva, Rubino, Ivana

“…Alzheimer's disease (AD) is a progressive, neurodegenerative disease that creates complex challenges and a significant burden for patients and caregivers…”
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Aggregation Promoting C-Terminal Truncation of α-Synuclein Is a Normal Cellular Process and Is Enhanced by the Familial Parkinson's Disease-Linked Mutations by Li, Wenxue, West, Neva, Colla, Emanuela, Pletnikova, Olga, Troncoso, Juan C., Marsh, Laura, Dawson, Ted M., Jäkälä, Pekka, Hartmann, Tobias, Price, Donald L., Lee, Michael K., Snyder, Solomon H.

“…Abnormal biology of α-synuclein (α-Syn) is directly implicated in the pathogenesis of Parkinson's disease and other α-synucleinopathies. Herein, we demonstrate…”
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Resistance to MPTP-neurotoxicity in α-synuclein knockout mice is complemented by human α-synuclein and associated with increased β-synuclein and Akt activation by Thomas, Bobby, Mandir, Allen S, West, Neva, Liu, Ying, Andrabi, Shaida A, Stirling, Wanda, Dawson, Valina L, Dawson, Ted M, Lee, Michael K

“…Genetic and biochemical abnormalities of α-synuclein are associated with the pathogenesis of Parkinson's disease. In the present study we investigated the in…”
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Reversal of dopaminergic degeneration in a parkinsonian rat following micrografting of human bone marrow-derived neural progenitors by Glavaski-Joksimovic, Aleksandra, Virag, Tamas, Chang, Qin A, West, Neva C, Mangatu, Thomas A, McGrogan, Michael P, Dugich-Djordjevic, Millicent, Bohn, Martha C

“…Parkinson's disease (PD) is a common neurodegenerative disease characterized by the selective loss of dopaminergic (DA) neurons in the midbrain. Various types…”
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An alpha-synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson's disease, but displays toxicity in dopamine neurons by Khodr, Christina E, Sapru, Mohan K, Pedapati, Jyothi, Han, Ye, West, Neva C, Kells, Adrian P, Bankiewicz, Krystof S, Bohn, Martha C

“…Abstract Effects of silencing ectopically expressed hSNCA in rat substantia nigra (SN) were examined as a novel therapeutic approach to Parkinson's disease…”
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Shared Protein Components of SINE RNPs by West, Neva C, Roy-Engel, Astrid M, Imataka, Hiroaki, Sonenberg, Nahum, Deininger, Prescott L

“…The heterogeneous, short RNAs produced from the high, copy, short mobile elements (SINEs) interact with proteins to form RNA–protein (RNP) complexes. In…”
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Correction: Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation by Thomas, Bobby, Mandir, Allen S., West, Neva, Liu, Ying, Andrabi, Shaida A., Stirling, Wanda, Dawson, Valina L., Dawson, Ted M., Lee, Michael K.

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Aβ deposition is associated with enhanced cortical α-synuclein lesions in Lewy body diseases by Pletnikova, Olga, West, Neva, Lee, Michael K., Rudow, Gay L., Skolasky, Richard L., Dawson, Ted M., Marsh, Laura, Troncoso, Juan C.

“…In order to understand better the neuropathological substrate of dementia in Parkinson's disease (PD) and to examine its interactions with Alzheimer's disease…”
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Resistance to MPTP-Neurotoxicity in [alpha]-Synuclein Knockout Mice Is Complemented by Human [alpha]-Synuclein and Associated with Increased [beta]-Synuclein and Akt Activation by Thomas, Bobby, Mandir, Allen S, West, Neva, Liu, Ying, Andrabi, Shaida A, Stirling, Wanda, Dawson, Valina L, Dawson, Ted M, Lee, Michael K

“…Genetic and biochemical abnormalities of [alpha]-synuclein are associated with the pathogenesis of Parkinson's disease. In the present study we investigated…”
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Lack of humoral immune response to the tetracycline (Tet) activator in rats injected intracranially with Tet-off rAAV vectors by Han, Y, Chang, Q A, Virag, T, West, N C, George, D, Castro, M G, Bohn, M C

“…The ability to safely control transgene expression from viral vectors is a long-term goal in the gene therapy field. We have previously reported tight…”
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Upstream flanking sequences and transcription of SINEs by Roy, A M, West, N C, Rao, A, Adhikari, P, Alemán, C, Barnes, A P, Deininger, P L

“…SINEs, short interspersed repeated DNA elements, undergo amplification through retroposition and subsequent integration into a new location in the genome. Each…”
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Abeta deposition is associated with enhanced cortical alpha-synuclein lesions in Lewy body diseases by Pletnikova, Olga, West, Neva, Lee, Michael K, Rudow, Gay L, Skolasky, Richard L, Dawson, Ted M, Marsh, Laura, Troncoso, Juan C

“…In order to understand better the neuropathological substrate of dementia in Parkinson's disease (PD) and to examine its interactions with Alzheimer's disease…”
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Upstream flanking sequences and transcription of SINEs 1 1Edited by M. Gottesman by Roy, Astrid M, West, Neva C, Rao, Aravinda, Adhikari, Prateek, Alemán, Claudina, Barnes, Anthony P, Deininger, Prescott L

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Purification, Expression and Binding Properties of BC1 Ribonucleoproteins by West, Neva Christina

“…Brain Cytoplasmic 1 (BC1) is a member of the short interspersed repetitive elements (SINEs) in rodent genomes. This class of elements is able to retropose…”
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