Search Results - "West, John T."

High prevalence of pre-existing serological cross-reactivity against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in sub-Saharan Africa by Tso, For Yue, Lidenge, Salum J., Peña, Phoebe B., Clegg, Ashley A., Ngowi, John R., Mwaiselage, Julius, Ngalamika, Owen, Julius, Peter, West, John T., Wood, Charles

“…•Cross-reactivity vs. SARS-CoV-2 high in sub-Saharan Africa pre-pandemic samples.•Reactivity against other human coronaviruses high in pre-COVID-19 pandemic…”
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Reduction of Kaposi's Sarcoma-Associated Herpesvirus Latency Using CRISPR-Cas9 To Edit the Latency-Associated Nuclear Antigen Gene by Tso, For Yue, West, John T, Wood, Charles

“…Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS), an AIDS-defining cancer in HIV-1-infected individuals or…”
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Presence of antibody-dependent cellular cytotoxicity (ADCC) against SARS-CoV-2 in COVID-19 plasma by Tso, For Yue, Lidenge, Salum J, Poppe, Lisa K, Peña, Phoebe B, Privatt, Sara R, Bennett, Sydney J, Ngowi, John R, Mwaiselage, Julius, Belshan, Michael, Siedlik, Jacob A, Raine, Morgan A, Ochoa, Juan B, Garcia-Diaz, Julia, Nossaman, Bobby, Buckner, Lyndsey, Roberts, W Mark, Dean, Matthew J, Ochoa, Augusto C, West, John T, Wood, Charles

“…Neutralizing-antibody (nAb) is the major focus of most ongoing COVID-19 vaccine trials. However, nAb response against SARS-CoV-2, when present, decays rapidly…”
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Antibody profiling and predictive modeling discriminate between Kaposi sarcoma and asymptomatic KSHV infection by Bennett, Sydney J, Yalcin, Dicle, Privatt, Sara R, Ngalamika, Owen, Lidenge, Salum J, West, John T, Wood, Charles

“…Protein-level immunodominance patterns against Kaposi sarcoma-associated herpesvirus (KSHV), the aetiologic agent of Kaposi sarcoma (KS), have been revealed…”
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Brain is a potential sanctuary for subtype C HIV-1 irrespective of ART treatment outcome by Tso, For Yue, Kang, Guobin, Kwon, Eun Hee, Julius, Peter, Li, Qingsheng, West, John T, Wood, Charles

“…Subtype C HIV-1 is responsible for the largest proportion of people living with HIV-1 infection. However, there is limited information about the roles of the…”
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Whole-Genome Sequencing of Kaposi's Sarcoma-Associated Herpesvirus from Zambian Kaposi's Sarcoma Biopsy Specimens Reveals Unique Viral Diversity by Olp, Landon N, Jeanniard, Adrien, Marimo, Clemence, West, John T, Wood, Charles

“…Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent for Kaposi's sarcoma (KS). Both KSHV and KS are endemic in sub-Saharan Africa where…”
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Relationship between the Cervical Microbiome, HIV Status, and Precancerous Lesions by Klein, Cameron, Gonzalez, Daniela, Samwel, Kandali, Kahesa, Crispin, Mwaiselage, Julius, Aluthge, Nirosh, Fernando, Samodha, West, John T, Wood, Charles, Angeletti, Peter C

“…Nearly all cervical cancers are causally associated with human papillomavirus (HPV). The burden of HPV-associated dysplasias in sub-Saharan Africa is…”
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Pancreatic cancer tumor microenvironment is a major therapeutic barrier and target by Hartupee, Conner, Nagalo, Bolni Marius, Chabu, Chiswili Y, Tesfay, Mulu Z, Coleman-Barnett, Joycelynn, West, John T, Moaven, Omeed

“…Pancreatic Ductal Adenocarcinoma (PDAC) is projected to become the 2nd leading cause of cancer-related deaths in the United States. Limitations in early…”
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Longitudinal Variations in Antibody Responses against SARS-CoV-2 Spike Epitopes upon Serial Vaccinations by Yalcin, Dicle, Bennett, Sydney J, Sheehan, Jared, Trauth, Amber J, Tso, For Yue, West, John T, Hagensee, Michael E, Ramsay, Alistair J, Wood, Charles

“…The COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) impacted healthcare, the workforce, and worldwide…”
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Antibody epitope profiling of the KSHV LANA protein using VirScan by Bennett, Sydney J, Yalcin, Dicle, Privatt, Sara R, Ngalamika, Owen, Lidenge, Salum J, West, John T, Wood, Charles

“…The humoral antibody response against Kaposi sarcoma-associated herpesvirus (KSHV) in infected individuals has been characterized demonstrating the…”
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Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC by Edmonds, Tara G, Ding, Haitao, Yuan, Xing, Wei, Qing, Smith, Kendra S, Conway, Joan A, Wieczorek, Lindsay, Brown, Bruce, Polonis, Victoria, West, John T, Montefiori, David C, Kappes, John C, Ochsenbauer, Christina

“…Abstract Effective vaccine development for human immunodeficiency virus type 1 (HIV-1) will require assays that ascertain the capacity of vaccine immunogens to…”
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How the Cervical Microbiota Contributes to Cervical Cancer Risk in Sub-Saharan Africa by Klein, Cameron, Kahesa, Crispin, Mwaiselage, Julius, West, John T, Wood, Charles, Angeletti, Peter C

“…Despite ongoing efforts, sub-Saharan Africa faces a higher cervical cancer burden than anywhere else in the world. Besides HPV infection, definitive factors of…”
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RNA-Seq of Kaposi's sarcoma reveals alterations in glucose and lipid metabolism by Tso, For Yue, Kossenkov, Andrew V, Lidenge, Salum J, Ngalamika, Owen, Ngowi, John R, Mwaiselage, Julius, Wickramasinghe, Jayamanna, Kwon, Eun Hee, West, John T, Lieberman, Paul M, Wood, Charles

“…Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent of Kaposi's sarcoma (KS). It is endemic in a number of sub-Saharan African countries with…”
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Yes-associated protein-1 overexpression in ocular surface squamous neoplasia; a potential diagnostic marker and therapeutic target by Julius, Peter, Siyumbwa, Stepfanie N, Maate, Fred, Moonga, Phyllis, Kang, Guobin, Kaile, Trevor, West, John T, Wood, Charles, Angeletti, Peter C

“…Yes-associated protein-1 (YAP-1) is a Hippo system transcription factor, which serves as an oncogene in squamous cell carcinoma, and several solid tumors when…”
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Upregulation of Cell Surface Glycoproteins in Correlation with KSHV LANA in the Kaposi Sarcoma Tumor Microenvironment by Privatt, Sara R, Ngalamika, Owen, Zhang, Jianshui, Li, Qinsheng, Wood, Charles, West, John T

“…HIV-associated epidemic Kaposi sarcoma (EpKS) remains one of the most prevalent cancers in sub-Saharan Africa despite the widespread uptake of anti-retroviral…”
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Comparative transcriptome analysis of endemic and epidemic Kaposi's sarcoma (KS) lesions and the secondary role of HIV-1 in KS pathogenesis by Lidenge, Salum J, Kossenkov, Andrew V, Tso, For Yue, Wickramasinghe, Jayamanna, Privatt, Sara R, Ngalamika, Owen, Ngowi, John R, Mwaiselage, Julius, Lieberman, Paul M, West, John T, Wood, Charles

“…In sub-Saharan Africa, endemic Kaposi's sarcoma (EnKS) is still prevalent despite high incidence of epidemic Kaposi's sarcoma (EpKS) resulting from the…”
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Viral Epitope Scanning Reveals Correlation between Seasonal HCoVs and SARS-CoV-2 Antibody Responses among Cancer and Non-Cancer Patients by Lidenge, Salum J, Yalcin, Dicle, Bennett, Sydney J, Ngalamika, Owen, Kweyamba, Brenda B, Mwita, Chacha J, Tso, For Yue, Mwaiselage, Julius, West, John T, Wood, Charles

“…Seasonal coronaviruses (HCoVs) are known to contribute to cross-reactive antibody (Ab) responses against SARS-CoV-2. While these responses are predictable due…”
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Subtype C HIV-1 reservoirs throughout the body in ART-suppressed individuals by Liu, Zhou, Julius, Peter, Kang, Guobin, West, John T, Wood, Charles

“…Subtype B HIV-1 reservoirs have been intensively investigated, but reservoirs in other subtypes and how they respond to antiretroviral therapy (ART) is…”
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The Kaposi's Sarcoma-Associated Herpesvirus (KSHV) gH/gL Complex Is the Predominant Neutralizing Antigenic Determinant in KSHV-Infected Individuals by Mortazavi, Yasaman, Lidenge, Salum J, Tran, Tara, West, John T, Wood, Charles, Tso, For Yue

“…Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of Kaposi's sarcoma (KS), one of the most prevalent cancers of people living with…”
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Prevalence of Kaposi's sarcoma-associated herpesvirus and transfusion-transmissible infections in Tanzanian blood donors by Lidenge, Salum J., Tran, Tara, Tso, For Yue, Ngowi, John R., Shea, Danielle M., Mwaiselage, Julius, Wood, Charles, West, John T.

“…•Kaposi's sarcoma-associated herpesvirus (KSHV) in Tanzania is high (56.9%).•Increased risk of KSHV infection in persons from the Lake and Central…”
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