Search Results - "West, Alexander"

Design and Evaluation of a Cyclobutane Diazirine Alkyne Tag for Photoaffinity Labeling in Cells by West, Alexander V., Amako, Yuka, Woo, Christina M.

“…Alkyl diazirines are frequently used in photoaffinity labeling to map small molecule–protein interactions in target identification studies. However, the alkyl…”
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Labeling Preferences of Diazirines with Protein Biomolecules by West, Alexander V, Muncipinto, Giovanni, Wu, Hung-Yi, Huang, Andrew C, Labenski, Matthew T, Jones, Lyn H, Woo, Christina M

“…Diazirines are widely used in photoaffinity labeling (PAL) to trap noncovalent interactions with biomolecules. However, design and interpretation of PAL…”
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cost of circadian desynchrony: Evidence, insights and open questions by West, Alexander C, Bechtold, David A

“…Coordinated daily rhythms are evident in most aspects of our physiology, driven by internal timing systems known as circadian clocks. Our understanding of how…”
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Evidence for circadian-based photoperiodic timekeeping in Svalbard ptarmigan, the northernmost resident bird by Appenroth, Daniel, Wagner, Gabriela C., Hazlerigg, David G., West, Alexander C.

“…The high Arctic archipelago of Svalbard (74°–81° north) experiences extended periods of uninterrupted daylight in summer and uninterrupted night in winter,…”
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Diversified regulation of circadian clock gene expression following whole genome duplication by West, Alexander C, Iversen, Marianne, Jørgensen, Even H, Sandve, Simen R, Hazlerigg, David G, Wood, Shona H

“…Across taxa, circadian control of physiology and behavior arises from cell-autonomous oscillations in gene expression, governed by a networks of so-called…”
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Misalignment with the external light environment drives metabolic and cardiac dysfunction by West, Alexander C., Smith, Laura, Ray, David W., Loudon, Andrew S. I., Brown, Timothy M., Bechtold, David A.

“…Most organisms use internal biological clocks to match behavioural and physiological processes to specific phases of the day–night cycle. Central to this is…”
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Photoaffinity Labeling Chemistries Used to Map Biomolecular Interactions by West, Alexander V., Woo, Christina M.

“…Photoaffinity labeling (PAL) is one of the few biochemical techniques that can give direct evidence of biomolecular interactions in cells. Several…”
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Tanycytes from a bird's eye view: gene expression profiling of the tanycytic region under different seasonal states in the Svalbard ptarmigan by Appenroth, Daniel, West, Alexander C, Wood, Shona H, Hazlerigg, David G

“…In mammals and birds, tanycytes are known to regulate thyroid hormone conversion, and this process is central to the control of seasonal reproduction. In…”
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Photoperiodic induction without light-mediated circadian entrainment in a High Arctic resident bird by Appenroth, Daniel, Melum, Vebjørn J, West, Alexander C, Dardente, Hugues, Hazlerigg, David G, Wagner, Gabriela C

“…Organisms use changes in photoperiod to anticipate and exploit favourable conditions in a seasonal environment. While species living at temperate latitudes…”
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Circadian coupling of mitochondria in a deep-diving mammal by Ciccone, Chiara, Kante, Fayiri, Folkow, Lars P, Hazlerigg, David G, West, Alexander C, Wood, Shona H

“…Regulation of mitochondrial oxidative phosphorylation is essential to match energy supply to changing cellular energy demands, and to cope with periods of…”
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Biological timekeeping in polar environments: lessons from terrestrial vertebrates by Hazlerigg, David G, Appenroth, Daniel, Tomotani, Barbara M, West, Alexander C, Wood, Shona H

“…The polar regions receive less solar energy than anywhere else on Earth, with the greatest year-round variation in daily light exposure; this produces highly…”
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The Reindeer Circadian Clock Is Rhythmic and Temperature-compensated But Shows Evidence of Weak Coupling Between the Secondary and Core Molecular Clock Loops by Appenroth, Daniel, Ravuri, Chandra S, Torppa, Sara K, Wood, Shona H, Hazlerigg, David G, West, Alexander C

“…Circadian rhythms synchronize the internal physiology of animals allowing them to anticipate daily changes in their environment. Arctic habitats may diminish…”
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Immunologic Profiling of the Atlantic Salmon Gill by Single Nuclei Transcriptomics by West, Alexander C, Mizoro, Yasutaka, Wood, Shona H, Ince, Louise M, Iversen, Marianne, Jørgensen, Even H, Nome, Torfinn, Sandve, Simen Rød, Martin, Samuel A M, Loudon, Andrew S I, Hazlerigg, David G

“…Anadromous salmonids begin life adapted to the freshwater environments of their natal streams before a developmental transition, known as smoltification,…”
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Colour as a signal for entraining the mammalian circadian clock by Walmsley, Lauren, Hanna, Lydia, Mouland, Josh, Martial, Franck, West, Alexander, Smedley, Andrew R, Bechtold, David A, Webb, Ann R, Lucas, Robert J, Brown, Timothy M

“…Twilight is characterised by changes in both quantity ("irradiance") and quality ("colour") of light. Animals use the variation in irradiance to adjust their…”
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A Novel Mechanism Controlling Resetting Speed of the Circadian Clock to Environmental Stimuli by Pilorz, Violetta, Cunningham, Peter S., Jackson, Anthony, West, Alexander C., Wager, Travis T., Loudon, Andrew S.I., Bechtold, David A.

“…Many aspects of mammalian physiology are driven through the coordinated action of internal circadian clocks. Clock speed (period) and phase (temporal…”
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Anugerah Sri Maharaja: Kumpulan Alihaksara dan Alihbahasa Prasasti-Prasasti Jawa Kuna dari Abad VIII-XI, by Edhie Wurjantoro by West, Alexander J

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Correction: RNA profiling identifies novel, photoperiod-history dependent markers associated with enhanced saltwater performance in juvenile Atlantic salmon by Iversen, Marianne, Mulugeta, Teshome, Blikeng, Børge Gellein, West, Alexander Christopher, Jørgensen, Even Hjalmar, Rød Sandve, Simen, Hazlerigg, David

“…[This corrects the article DOI: 10.1371/journal.pone.0227496.]…”
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RNA profiling identifies novel, photoperiod-history dependent markers associated with enhanced saltwater performance in juvenile Atlantic salmon by Iversen, Marianne, Mulugeta, Teshome, Gellein Blikeng, Børge, West, Alexander Christopher, Jørgensen, Even Hjalmar, Rød Sandven, Simen, Hazlerigg, David

“…Atlantic salmon migrate to sea following completion of a developmental process known as smolting, which establishes a seawater (SW) tolerant phenotype…”
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Methods of Sentinel Lymph Node Detection and Management in Urinary Bladder Cancer-A Narrative Review by Sinha, Ankit, West, Alexander, Hayes, John, Teoh, Jeremy, Decaestecker, Karel, Vasdev, Nikhil

“…Detection of lymph node status in bladder cancer significantly impacts clinical decisions regarding its management. There is a wide range of detection…”
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Newly expressed SUR1-regulated NCCa-ATP channel mediates cerebral edema after ischemic stroke by Simard, J Marc, Chen, Mingkui, Tarasov, Kirill V, Bhatta, Sergei, Ivanova, Svetlana, Melnitchenko, Ludmila, Tsymbalyuk, Natalya, West, G Alexander, Gerzanich, Volodymyr

“…Pathological conditions in the central nervous system, including stroke and trauma, are often exacerbated by cerebral edema. We recently identified a…”
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