Search Results - "Wessels, Hans J."
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Nitric oxide-dependent anaerobic ammonium oxidation
Published in Nature communications (18-03-2019)“…Nitric oxide (NO) has important functions in biology and atmospheric chemistry as a toxin, signaling molecule, ozone depleting agent and the precursor of the…”
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The Assembly Pathway of Mitochondrial Respiratory Chain Complex I
Published in Cell metabolism (10-01-2017)“…Mitochondrial complex I is the largest integral membrane enzyme of the respiratory chain and consists of 44 different subunits encoded in the mitochondrial and…”
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Chemically triggered drug release from an antibody-drug conjugate leads to potent antitumour activity in mice
Published in Nature communications (04-05-2018)“…Current antibody-drug conjugates (ADCs) target internalising receptors on cancer cells leading to intracellular drug release. Typically, only a subset of…”
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Nitrite-driven anaerobic methane oxidation by oxygenic bacteria
Published in Nature (London) (25-03-2010)“…Only three biological pathways are known to produce oxygen: photosynthesis, chlorate respiration and the detoxification of reactive oxygen species. Here we…”
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Mixed-phase weak anion-exchange/reversed-phase LC–MS/MS for analysis of nucleotide sugars in human fibroblasts
Published in Analytical and bioanalytical chemistry (01-06-2024)“…Nucleotide sugars (NS) fulfil important roles in all living organisms and in humans, related defects result in severe clinical syndromes. NS can be seen as the…”
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The GlycoPaSER Prototype as a Real-Time N-Glycopeptide Identification Tool Based on the PaSER Parallel Computing Platform
Published in International journal of molecular sciences (26-04-2023)“…Real-time database searching allows for simpler and automated proteomics workflows as it eliminates technical bottlenecks in high-throughput experiments. Most…”
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Site-Specific, Platform-Based Conjugation Strategy for the Synthesis of Dual-Labeled Immunoconjugates for Bimodal PET/NIRF Imaging of HER2-Positive Tumors
Published in Bioconjugate chemistry (16-03-2022)“…Because positron emission tomography (PET) and optical imaging are very complementary, the combination of these two imaging modalities is very enticing in the…”
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Author Correction: Nitric oxide-dependent anaerobic ammonium oxidation
Published in Nature communications (07-06-2022)Get full text
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The metagenome of the marine anammox bacterium 'Candidatus Scalindua profunda' illustrates the versatility of this globally important nitrogen cycle bacterium
Published in Environmental microbiology (01-05-2013)“…Summary Anaerobic ammonium‐oxidizing (anammox) bacteria are responsible for a significant portion of the loss of fixed nitrogen from the oceans, making them…”
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Glycoproteomics in Cerebrospinal Fluid Reveals Brain-Specific Glycosylation Changes
Published in International journal of molecular sciences (18-01-2023)“…The glycosylation of proteins plays an important role in neurological development and disease. Glycoproteomic studies on cerebrospinal fluid (CSF) are a…”
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In Vitro Skeletal Muscle Model of PGM1 Deficiency Reveals Altered Energy Homeostasis
Published in International journal of molecular sciences (04-05-2023)“…Phosphoglucomutase 1 (PGM1) is a key enzyme for the regulation of energy metabolism from glycogen and glycolysis, as it catalyzes the interconversion of…”
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Whole cell formaldehyde cross-linking simplifies purification of mitochondrial nucleoids and associated proteins involved in mitochondrial gene expression
Published in PloS one (19-02-2015)“…Mitochondrial DNA/protein complexes (nucleoids) appear as discrete entities inside the mitochondrial network when observed by live-cell imaging and…”
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Proteomics-identified Bvg-activated autotransporters protect against bordetella pertussis in a mouse model
Published in PloS one (18-08-2014)“…Pertussis is a highly infectious respiratory disease of humans caused by the bacterium Bordetella pertussis. Despite high vaccination coverage, pertussis has…”
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Publisher Correction: Nitric oxide-dependent anaerobic ammonium oxidation
Published in Nature communications (18-04-2019)“…The original HTML version of this Article had an incorrect Published online date of 20 March 2019; it should have been 18 March 2019. This has been corrected…”
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Biallelic variants in SLC35C1 as a cause of isolated short stature with intellectual disability
Published in Journal of human genetics (01-09-2020)“…Variants in SLC35C1 underlie leucocyte adhesion deficiency (LADII) or congenital disorder of glycosylation type 2c (CDGIIc), an autosomal recessive disorder of…”
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Enrichment and characterization of a nitric oxide-reducing microbial community in a continuous bioreactor
Published in Nature microbiology (01-08-2023)“…Nitric oxide (NO) is a highly reactive and climate-active molecule and a key intermediate in the microbial nitrogen cycle. Despite its role in the evolution of…”
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Publisher Correction: Enrichment and characterization of a nitric oxide-reducing microbial community in a continuous bioreactor
Published in Nature microbiology (01-06-2024)Get full text
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18
Evolution of a new enzyme for carbon disulphide conversion by an acidothermophilic archaeon
Published in Nature (London) (20-10-2011)“…Evolution of novel enzyme activity Many extremophilic organisms require unusual enzymes to help them survive in harsh environments. For example, acid-loving…”
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Mutations in NDUFAF3 (C3ORF60), Encoding an NDUFAF4 (C6ORF66)-Interacting Complex I Assembly Protein, Cause Fatal Neonatal Mitochondrial Disease
Published in American journal of human genetics (12-06-2009)“…Mitochondrial complex I deficiency is the most prevalent and least understood disorder of the oxidative phosphorylation system. The genetic cause of many cases…”
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Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function
Published in Cell reports (Cambridge) (13-09-2016)“…Dendritic cells (DCs) play a key role in orchestrating adaptive immune responses. In human blood, three distinct subsets exist: plasmacytoid DCs (pDCs) and…”
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