Search Results - "Wessels, D. H."

Pharmacokinetic and glucodynamic variability : assessment of insulin glargine, NPH insulin and insulin ultralente in healthy volunteers using a euglycaemic clamp technique by SCHOLTZ, H. E, PRETORIUS, S. G, WESSELS, D. H, BECKER, R. H. A

“…This single-dose, double-blind, randomised, parallel-group study evaluated the reproducibility in systemic exposure and glucodynamic effect of insulin…”
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Pharmacokinetics of the New Ketolide Telithromycin (HMR 3647) Administered in Ascending Single and Multiple Doses by NAMOUR, F, WESSELS, D. H, PASCUAL, M. H, REYNOLDS, D, SULTAN, E, LENFANT, B

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Biotransformation of insulin glargine after subcutaneous injection in healthy subjects by Kuerzel, G. U., Shukla, U., Scholtz, H. E., Pretorius, S. G., Wessels, D. H., Venter, C., Potgieter, M. A., Lang, A. M., Koose, T., Bernhardt, E.

“…Summary Objective: It is important to establish pharmacokinetic or pharmacodynamic differences between novel insulin analogues and human insulin. This study…”
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Pharmacokinetics and absolute oral bioavailability of an 800-mg oral dose of telithromycin in healthy young and elderly volunteers by Perret, C, Lenfant, B, Weinling, E, Wessels, D H, Scholtz, H E, Montay, G, Sultan, E

“…This two-way, randomized, single-dose, crossover study determined the pharmacokinetics and absolute oral bioavailability of telithromycin in young and elderly…”
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Equipotency of insulin glargine and regular human insulin on glucose disposal in healthy subjects following intravenous infusion by SCHOLTZ, H. E, PRETORIUS, S. G, WESSELS, D. H, VENTER, C, POTGIETER, M. A, BECKER, R. H. A

“…The absolute glucose disposal of insulin glargine (Lantus) was compared to that of regular human insulin in healthy subjects (n=20) using the euglycaemic clamp…”
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PI-46 by Lambert, J. R., Duliege, A. M., Stead, R., Wessels, D. H., Pcikup, E. M., Iwashita, J., Leuther, K., Woodburn, K., Schatz, P., Naso, R.

“…BACKGROUND/AIM Hematide is a synthetic, PEGylated, peptidic ESA that binds to and activates the erythropoietin (EPO) receptor. Hematide has comparable in vitro…”
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A randomised, double blind, placebo controlled single ascending dose study of PYM50018, with an open label cross-over stage to assess food effect by Wessels, D. H., Grover, R., Frend, A., Levene, S., Potgieter, L.

“…Background and Aims PYM50018 has neuroprotective properties and an emerging safety profile that make it a promising candidate for the treatment of…”
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