Search Results - "Wessel, Thomas C."
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Erythropoietin therapy for acute stroke is both safe and beneficial
Published in Molecular medicine (Cambridge, Mass.) (01-08-2002)“…Erythropoietin (EPO) and its receptor play a major role in embryonic brain, are weakly expressed in normal postnatal/adult brain and up-regulated upon…”
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2
Nightly treatment of primary insomnia with eszopiclone for six months : Effect on sleep, quality of life, and work limitations
Published in Sleep (New York, N.Y.) (01-08-2007)“…To evaluate 6 months' eszopiclone treatment upon patient-reported sleep, fatigue and sleepiness, insomnia severity, quality of life, and work limitations…”
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Sustained efficacy of eszopiclone over 6 months of nightly treatment: Results of a Randomized, double-blind, placebo-controlled study in adults with chronic insomnia
Published in Sleep (New York, N.Y.) (01-11-2003)“…To determine the long-term efficacy of eszopiclone in patients with chronic insomnia. Randomized, double-blind, multicenter, placebo-controlled. Out-patient,…”
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4
A Post Hoc Analysis of the Effect of Nightly Administration of Eszopiclone and a Selective Serotonin Reuptake Inhibitor in Patients With Insomnia and Anxious Depression
Published in The journal of clinical psychiatry (01-04-2011)“…Patients with major depressive disorder (MDD) and significant anxiety are less responsive to antidepressants than those without anxiety. In this post hoc…”
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5
A 2-week efficacy and safety study of eszopiclone in elderly patients with primary insomnia
Published in Sleep (New York, N.Y.) (01-06-2005)“…Evaluate the efficacy of eszopiclone in primary insomnia. Randomized, double-blind, placebo-controlled multicenter in outpatient setting with weekly visits…”
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In situ hybridization analysis of c-fos and c-jun expression in the rat brain following transient forebrain ischemia
Published in Brain research (20-12-1991)“…Early induction of the mRNAs encoding the c-Fos and c-Jun nuclear proteins was examined in rat brain by in situ hybridization at various timepoints following…”
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7
Localization of monoamine oxidase A and B mRNA in the rat brain by in situ hybridization
Published in Synapse (New York, N.Y.) (01-01-1997)“…Monoamine oxidases A and B (MAOA and MAOB) are the major catabolic isoenzymes of catecholamines and serotonin in the mammalian brain. Although the distribution…”
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8
Nitrous Oxide Modulator: Lubeluzole
Published in Current medical research and opinion (2002)“…SUMMARY Lubeluzole was developed as a neuroprotective substance for use in acute ischaemic stroke. Its biological function is related to its ability to alter…”
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9
A Dual Role for the cAMP-Dependent Protein Kinase in Tyrosine Hydroxylase Gene Expression
Published in Proceedings of the National Academy of Sciences - PNAS (15-04-1993)“…Tyrosine hydroxylase (TH) catalyzes the conversion of L-tyrosine to 3,4-dihydroxy-L-phenylalanine, the first and rate-limiting step in catecholamine…”
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10
Temporal pattern of internucleosomal DNA fragmentation in the striatum and hippocampus after transient forebrain ischemia
Published in Neuroscience letters (17-02-1995)“…Transient forebrain ischemia in rodents caused internucleosomal DNA fragmentation that appeared in the striatum 24 h after reperfusion, and in the hippocampus…”
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Delayed histopathological neuronal damage in the substantia nigra compacta (nucleus A9) after transient forebrain ischaemia
Published in Neurobiology of disease (01-04-1995)“…Neurones in the rat substantia nigra compacta (SNC) are initially resistant to transient forebrain ischaemia in contrast to vulnerable neurones in the striatum…”
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12
Fatigue across the CNS spectrum: a clinical review
Published in Fatigue (Abingdon, Eng.) (02-10-2014)“…Fatigue is reflected in a broad array of symptoms that can be particularly impactful in patients with central nervous system (CNS) disorders. Fatigue symptoms…”
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13
The Sustained 6-Month Efficacy of Eszopiclone in the Treatment of Chronic Insomnia
Published in Sleep (New York, N.Y.) (15-03-2004)Get full text
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14
Increased c-fos expression in nucleus of the solitary tract correlated with conditioned taste aversion to sucrose in rats
Published in Neuroscience letters (19-05-1994)“…The pattern of neuronal activation in the rat nucleus of the solitary tract (NTS) in response to a standard gustatory stimulus was examined using c-Fos-like…”
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15
Differential in vivo regulation of mRNA encoding the norepinephrine transporter and tyrosine hydroxylase in rat adrenal medulla and locus ceruleus
Published in Journal of neurochemistry (01-08-1995)“…To investigate the regulation of norepinephrine transporter mRNA in vivo, we analyzed the effects of reserpine on its expression in the rat adrenal medulla and…”
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Transient forebrain ischemia induces delayed injury in the substantia nigra reticulata: degeneration of GABA neurons, compensatory expression of GAD mRNA
Published in Brain research (18-04-1994)“…In rodents, transient forebrain ischemia causes preferentially neuron death in small and medium size neurons of the striatum and hilar neurons in the…”
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17
Alternate promoters in the rat aromatic L-amino acid decarboxylase gene for neuronal and nonneuronal expression: an in situ hybridization study
Published in Journal of neurochemistry (01-01-1996)“…Aromatic L-amino acid decarboxylase (AADC) is found in both neuronal cells and nonneuronal cells, and a single gene encodes rat AADC in both neuronal and…”
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18
Differential spatial and temporal gene expression in response to axotomy and deafferentation following transection of the medial forebrain bundle
Published in The Journal of neuroscience (01-08-1993)“…Alterations in the levels of neurotransmitter biosynthetic enzymes are a concomitant of many neurodegenerative disorders. In order to elucidate potential…”
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Expression of catecholamine-synthesizing enzymes, peptidylglycine [alpha]-amidating monooxygenase, and neuropeptide Y mRNA in the rat adrenal medulla after acute systemic nicotine
Published in Journal of molecular neuroscience (01-02-1997)“…The expression of catecholamine-synthesizing enzymes in the adrenal medulla is upregulated in parallel by stress and pharmacological treatments. In this study…”
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Acute effects of reserpine on tryptophan hydroxylase activity and mRNA in rat brain
Published in Brain research (27-08-1993)“…The present study examined changes in tryptophan hydroxylase (TPH) activity in the rat brainstem 1-4 days after i.p. reserpine administration. TPH enzyme…”
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