Search Results - "Wessel, Howard"

Neuroprotection mediated by ST266 requires full complement of proteins secreted by amnion-derived multipotent progenitor cells by Willett, Keirnan, Khan, Reas S, Dine, Kimberly, Wessel, Howard, Kirshner, Ziv Z, Sauer, Jodie L, Ellis, Ashley, Brown, Larry R, Shindler, Kenneth S

“…ST266 is the biological secretome of cultured Amnion-derived Multipotent Progenitor cells containing multiple growth factors and cytokines. While…”
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Exploratory Phase II Multicenter, Open-Label, Clinical Trial of ST266, a Novel Secretome for Treatment of Persistent Corneal Epithelial Defects by Jeng, Bennie H, Hamrah, Pedram, Kirshner, Ziv Z, Mendez, Benjamin C, Wessel, Howard C, Brown, Larry R, Steed, David L

“…An exploratory phase II, multicenter, open-label, clinical trial (NCT03687632) was conducted to evaluate the safety and effectiveness in treating persistent…”
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Correlation of surrogate markers of Gaucher disease. Implications for long-term follow up of enzyme replacement therapy by Cabrera-Salazar, Mario A, O'Rourke, Erin, Henderson, Nadene, Wessel, Howard, Barranger, John A

“…Background: The excessive storage of cellular debris in the lysosomal storage disorders triggers a variety of cellular responses. Some of these responses are…”
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The novel secretome ST266 activates Akt and protects against oxidative stress-mediated injury in human RPE and Müller cells by Tang, Alan C., Besley, Nicholas A., Trimpey-Warfhatig, Rose, Yang, Ping, Wessel, Howard, Brown, Larry, Kirshner, Ziv, Jaffe, Glenn J.

“…Oxidative stress-mediated retinal pigment epithelial (RPE) cell damage is associated with age-related macular degeneration (AMD). ST266 is the biological…”
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RGC Neuroprotection Following Optic Nerve Trauma Mediated By Intranasal Delivery of Amnion Cell Secretome by Grinblat, Gabriela A, Khan, Reas S, Dine, Kimberly, Wessel, Howard, Brown, Larry, Shindler, Kenneth S

“…Intranasally delivered ST266, the biological, proteinaceous secretome of amnion-derived multipotent progenitor cells, reduces retinal ganglion cell (RGC) loss,…”
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Intranasal Delivery of A Novel Amnion Cell Secretome Prevents Neuronal Damage and Preserves Function In A Mouse Multiple Sclerosis Model by Khan, Reas S., Dine, Kimberly, Bauman, Bailey, Lorentsen, Michael, Lin, Lisa, Brown, Helayna, Hanson, Leah R., Svitak, Aleta L., Wessel, Howard, Brown, Larry, Shindler, Kenneth S.

“…The ability of a novel intranasally delivered amnion cell derived biologic to suppress inflammation, prevent neuronal damage and preserve neurologic function…”
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Effects of Varying Intranasal Treatment Regimens in ST266-Mediated Retinal Ganglion Cell Neuroprotection by Khan, Reas S, Dine, Kimberly, Wessel, Howard, Brown, Larry, Shindler, Kenneth S

“…INTRODUCTION:Previous studies have shown that intranasally administered ST266, a novel biological secretome of amnion‐derived multipotent progenitor cells…”
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The administration of amnion-derived multipotent cell secretome ST266 protects against necrotizing enterocolitis in mice and piglets by Sodhi, Chhinder P, Ahmad, Raheel, Jia, Hongpeng, Fulton, William B, Lopez, Carla, Gonzalez Salazar, Andres J, Ishiyama, Asuka, Sampah, Maame, Steinway, Steve, Wang, Sanxia, Prindle, Jr, Thomas, Wang, Menghan, Steed, David L, Wessel, Howard, Kirshner, Ziv, Brown, Larry R, Lu, Peng, Hackam, David J

“…Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease in premature infants and is steadily rising in frequency. Patients…”
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Effects of Varying Intranasal Treatment Regimens in ST266-Mediated RGC Neuroprotection by Khan, Reas S., Dine, Kimberly, Wessel, Howard, Brown, Larry, Shindler, Kenneth S.

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Type XII collagen contributes to diversities in human corneal and limbal extracellular matrices by Wessel, H, Anderson, S, Fite, D, Halvas, E, Hempel, J, SundarRaj, N

“…To characterize diversities in the extracelhtlar matrices (ECMs) of the corneal and the surrounding limbal epithelium and stroma. Immunohistochemical analyses…”
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Developmentally Regulated Appearance of Spliced Variants of Type XII Collagen in the Cornea by Anderson, Susan, SundarRaj, Sonali, Fite, Dana, Wessel, Howard, SundarRaj, Nirmala

“…To determine whether temporal and spatial changes in the distribution of the long and short alternatively spliced variants of type XII collagen are associated…”
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A Rho-associated protein kinase: differentially distributed in limbal and corneal epithelia by SundarRaj, N, Kinchington, PR, Wessel, H, Goldblatt, B, Hassell, J, Vergnes, JP, Anderson, SC

“…The authors have developed monoclonal antibodies (mAbs) to characterize the sequential biochemical changes in corneal epithelial cells after they differentiate…”
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