A small-scale robotic manipulandum for motor training in stroke rats

The investigation and characterization of sensori-motor learning and execution represents a key objective for the design of optimal rehabilitation therapies following stroke. By supplying new tools to investigate sensorimotor learning and objectively assess recovery, robot assisted techniques have o...

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Published in:2011 IEEE International Conference on Rehabilitation Robotics Vol. 2011; pp. 1 - 7
Main Authors: Vigaru, B., Lambercy, O., Graber, L., Fluit, R., Wespe, P., Schubring-Giese, M., Luft, A., Gassert, R.
Format: Conference Proceeding Journal Article
Language:English
Published: United States IEEE 01-01-2011
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Summary:The investigation and characterization of sensori-motor learning and execution represents a key objective for the design of optimal rehabilitation therapies following stroke. By supplying new tools to investigate sensorimotor learning and objectively assess recovery, robot assisted techniques have opened new lines of research in neurorehabilitation aiming to complement current clinical strategies. Human studies, however, are limited by the complex logistics, heterogeneous patient populations and large dropout rates. Rat models may provide a substitute to explore the mechanisms underlying these processes in humans with larger and more homogeneous populations. This paper describes the development and evaluation of a three-degrees-of-freedom robotic manipulandum to train and assess precision forelimb movement in rats before and after stroke. The mechanical design is presented based on the requirements of interaction with rat kinematics and kinetics. The characterization of the robot exhibits a compact, low friction device, with a sufficient bandwidth suitable for motor training studies with rodents. The manipulandum was integrated with an existing training environment for rodent experiments and a first study is currently underway.
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ISBN:1424498635
9781424498635
ISSN:1945-7898
1945-7901
DOI:10.1109/ICORR.2011.5975349