Search Results - "Wesolowska, Olga"

Interaction of phenothiazines, stilbenes and flavonoids with multidrug resistance-associated transporters, P-glycoprotein and MRP1 by Wesołowska, Olga

“…Multidrug resistance (MDR) of cancer cells poses a serious obstacle to successful chemotherapy. The overexpression of multispecific ATP-binding cassette…”
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Isobavachalcone as an Active Membrane Perturbing Agent and Inhibitor of ABCB1 Multidrug Transporter by Palko-Łabuz, Anna, Błaszczyk, Maria, Środa-Pomianek, Kamila, Wesołowska, Olga

“…Isobavachalcone (IBC) is an active substance from the medicinal plant Psoralea corylifolia. This prenylated chalcone was reported to possess antioxidative,…”
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Interaction of selected alkoxy naringenin oximes with model and bacterial membranes by Wesołowska, Olga, Duda-Madej, Anna, Błaszczyk, Maria, Środa-Pomianek, Kamila, Kozłowska, Joanna, Anioł, Mirosław

“…Naringenin is a flavonoid found in many fruits and herbs, most notably in grapefruits. In recent years, this compound and its derivatives have been of great…”
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MDR reversal and pro-apoptotic effects of statins and statins combined with flavonoids in colon cancer cells by Palko-Łabuz, Anna, Środa-Pomianek, Kamila, Wesołowska, Olga, Kostrzewa-Susłow, Edyta, Uryga, Anna, Michalak, Krystyna

“…[Display omitted] •Simvastatin and mevastatin inhibit proliferation of LoVo and LoVo/Dx cancer cells.•Antiproliferative effect is accompanied by apoptosis…”
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Conjugation with Phospholipids as a Modification Increasing Anticancer Activity of Phenolic Acids in Metastatic Melanoma-In Vitro and In Silico Studies by Palko-Łabuz, Anna, Gliszczyńska, Anna, Skonieczna, Magdalena, Poła, Andrzej, Wesołowska, Olga, Środa-Pomianek, Kamila

“…Phenolic acids possess many beneficial biological activities, including antioxidant and anti-inflammatory properties. Unfortunately, their low bioavailability…”
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Polyphenols counteract tumor cell chemoresistance conferred by multidrug resistance proteins by Michalak, Krystyna, Wesolowska, Olga

“…One of the main reasons of cancer resistance to chemotherapeutic treatment is the presence of different ABC multidrug transporters in plasma membranes. The…”
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Pretreatment of Melanoma Cells with Aqueous Ethanol Extract from Madhuca longifolia Bark Strongly Potentiates the Activity of a Low Dose of Dacarbazine by Środa-Pomianek, Kamila, Barycka, Anna, Gleńsk, Michał, Rajbhandari, Meena, Skonieczna, Magdalena, Palko-Łabuz, Anna, Wesołowska, Olga

“…is an evergreen tree distributed in India, Nepal, and Sri Lanka. This tree is commonly known as Mahua and is used in traditional medicine. It was demonstrated…”
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Modulators of cellular cholesterol homeostasis as antiproliferative and model membranes perturbing agents by Błaszczyk, Maria, Kozioł, Agata, Palko-Łabuz, Anna, Środa-Pomianek, Kamila, Wesołowska, Olga

“…Cholesterol is an important component of mammalian cell membranes affecting their fluidity and permeability. Together with sphingomyelin, cholesterol forms…”
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Organosilicon Compounds, SILA-409 and SILA-421, as Doxorubicin Resistance-Reversing Agents in Human Colon Cancer Cells by Wesołowska, Olga, Michalak, Krystyna, Błaszczyk, Maria, Molnár, Joseph, Środa-Pomianek, Kamila

“…Multidrug resistance (MDR) that occurs in cancer cells constitutes one of the major reasons for chemotherapy failure. The main molecular mechanism of MDR is…”
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Methoxychalcones as potential anticancer agents for colon cancer: Is membrane perturbing potency relevant? by Palko-Łabuz, Anna, Wesołowska, Olga, Błaszczyk, Maria, Uryga, Anna, Sobieszczańska, Beata, Skonieczna, Magdalena, Kostrzewa-Susłow, Edyta, Janeczko, Tomasz, Środa-Pomianek, Kamila

“…Chalcones are naturally produced by many plants, and constitute precursors for the synthesis of flavons and flavanons. They were shown to possess…”
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Interaction of prenylated chalcones and flavanones from common hop with phosphatidylcholine model membranes by Wesołowska, Olga, Gąsiorowska, Justyna, Petrus, Joanna, Czarnik-Matusewicz, Bogusława, Michalak, Krystyna

“…Common hop (Humulus lupulus) constitutes a source of numerous prenylated chalcones such as xanthohumol (XH) and flavanones such as 8-prenylnaringenin (8-PN)…”
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Newly Obtained Apple Pectin as an Adjunct to Irinotecan Therapy of Colorectal Cancer Reducing E. coli Adherence and β-Glucuronidase Activity by Palko-Łabuz, Anna, Maksymowicz, Jerzy, Sobieszczańska, Beata, Wikiera, Agnieszka, Skonieczna, Magdalena, Wesołowska, Olga, Środa-Pomianek, Kamila

“…Colorectal cancer (CRC) is the second cause of cancer death worldwide. The composition and enzymatic activity of colonic microbiota can significantly affect…”
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The Combined Use of Phenothiazines and Statins Strongly Affects Doxorubicin-Resistance, Apoptosis, and Cox-2 Activity in Colon Cancer Cells by Środa-Pomianek, Kamila, Michalak, Krystyna, Palko-Łabuz, Anna, Uryga, Anna, Świątek, Piotr, Majkowski, Michał, Wesołowska, Olga

“…Since none of the multidrug resistance (MDR) modulators tested so far found their way into clinic, a novel approach to overcome the MDR of cancer cells has…”
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Simvastatin Strongly Augments Proapoptotic, Anti-inflammatory and Cytotoxic Activity of Oxicam Derivatives in Doxorubicin-resistant Colon Cancer Cells by Środa-Pomianek, Kamila, Michalak, Krystyna, Palko-Łabuz, Anna, Uryga, Anna, Szczęśniak-Sięga, Berenika, Wesołowska, Olga

“…Incidence of cancer is still increasing. Chemotherapy is often unsuccessful; moreover, anticancer drugs cause serious side-effects. It is necessary to develop…”
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TMPE Derived from Saffron Natural Monoterpene as Cytotoxic and Multidrug Resistance Reversing Agent in Colon Cancer Cells by Środa-Pomianek, Kamila, Palko-Łabuz, Anna, Poła, Andrzej, Ferens-Sieczkowska, Mirosława, Wesołowska, Olga, Kozioł, Agata

“…Terpenes constitute one of the largest groups of natural products. They exhibit a wide range of biological activities including antioxidant, anticancer, and…”
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Increased lipid peroxidation, apoptosis and selective cytotoxicity in colon cancer cell line LoVo and its doxorubicin-resistant subline LoVo/Dx in the presence of newly synthesized phenothiazine derivatives by Środa-Pomianek, Kamila, Michalak, Krystyna, Świątek, Piotr, Poła, Andrzej, Palko-Łabuz, Anna, Wesołowska, Olga

“…[Display omitted] Cancer cells often develop the resistance to pro-apoptotic signaling that makes them invulnerable to conventional treatment. Therapeutic…”
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The Use of Endo-Cellulase and Endo-Xylanase for the Extraction of Apple Pectins as Factors Modifying Their Anticancer Properties and Affecting Their Synergy with the Active Form of Irinotecan by Maksymowicz, Jerzy, Palko-Łabuz, Anna, Sobieszczańska, Beata, Chmielarz, Mateusz, Ferens-Sieczkowska, Mirosława, Skonieczna, Magdalena, Wikiera, Agnieszka, Wesołowska, Olga, Środa-Pomianek, Kamila

“…Pectin constitutes an essential component of dietary fiber. Modified pectins from various sources possess potent anticancer and immunomodulatory activities. In…”
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Interaction of the chemopreventive agent resveratrol and its metabolite, piceatannol, with model membranes by Wesołowska, Olga, Kużdżał, Michał, Štrancar, Janez, Michalak, Krystyna

“…Resveratrol and piceatannol are plant-derived polyphenols possessing extremely wide range of biological activities such as cancer chemopreventive, cardio- and…”
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Cytotoxic and multidrug resistance reversal activity of phenothiazine derivative is strongly enhanced by theobromine, a phytochemical from cocoa by Środa-Pomianek, Kamila, Michalak, Krystyna, Palko-Łabuz, Anna, Poła, Andrzej, Dzięgiel, Piotr, Puła, Bartosz, Świątek, Piotr, Wesołowska, Olga

“…The idea of the use of anticancer drugs together with a chemosensitizer emerged as the strategy of reversal of multidrug resistance (MDR) of cancer cells…”
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Giant unilamellar vesicles - a perfect tool to visualize phase separation and lipid rafts in model systems by Wesołowska, Olga, Michalak, Krystyna, Maniewska, Jadwiga, Hendrich, Andrzej B

“…Model systems such as black lipid membranes or conventional uni- or multilamellar liposomes are commonly used to study membrane properties and structure…”
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