Search Results - "Wesam H. Abdulaal"

Prospects of IL-2 in Cancer Immunotherapy by Jamal, Mohammad Sarwar, Rasool, Mahmood, Mahmoud, Maged Mostafa, Wu, Wei, Zamzami, Mazin A., Zeyadi, Mustafa, Abdulaal, Wesam H., Helmi, Nawal, Choudhry, Hani, Warsi, Mohiuddin K.

“…IL-2 is a powerful immune growth factor and it plays important role in sustaining T cell response. The potential of IL-2 in expanding T cells without loss of…”
Get full text

Cerium oxide nanoparticles impact on sepsis-induced cerebral injury: Deciphering miRNA / NF-κB/TLR signalling pathway by Wesam H. Abdulaal, Nawal Helmi, Amal Hamza, Neveen A. Salem

Get full text

Wasp venom peptide improves the proapoptotic activity of alendronate sodium in A549 lung cancer cells by Alhakamy, Nabil A, Okbazghi, Solomon Z, A Alfaleh, Mohamed, H Abdulaal, Wesam, Bakhaidar, Rana B, Alselami, Mohammed O, Zahrani, Majed Al, Alqarni, Hani M, F Alghaith, Adel, Alshehri, Sultan, Badr-Eldin, Shaimaa M, Aldawsari, Hibah M, Al-Hejaili, Omar D, Aldhabi, Bander M, Mahdi, Wael A

“…Lung cancer in men and women is considered the leading cause for cancer-related mortality worldwide. Anti-cancer peptides represent a potential untapped…”
Get full text

Untargeted Metabolic Profiling of Extracellular Vesicles of SARS-CoV-2-Infected Patients Shows Presence of Potent Anti-Inflammatory Metabolites by Alzahrani, Faisal A., Shait Mohammed, Mohammed Razeeth, Alkarim, Saleh, Azhar, Esam I., El-Magd, Mohammed A., Hawsawi, Yousef, Abdulaal, Wesam H., Yusuf, Abdulaziz, Alhatmi, Abdulaziz, Albiheyri, Raed, Fakhurji, Burhan, Kurdi, Bassem, Madani, Tariq A., Alguridi, Hassan, Alosaimi, Roaa S., Khan, Mohammad Imran

“…Extracellular vesicles (EVs) carry important biomolecules, including metabolites, and contribute to the spread and pathogenesis of some viruses. However, to…”
Get full text

Microneedles Drug Delivery Systems for Treatment of Cancer: A Recent Update by Seetharam, Aravindram Attiguppe, Choudhry, Hani, Bakhrebah, Muhammed A., Abdulaal, Wesam H., Gupta, Maram Suresh, Rizvi, Syed Mohd Danish, Alam, Qamre, Siddaramaiah, Gowda, Devegowda Vishakante, Moin, Afrasim

“…Microneedles (MNs) are tiny needle like structures used in drug delivery through layers of the skin. They are non-invasive and are associated with…”
Get full text

Determinants of breast cancer in Saudi women from Makkah region: a case-control study (breast cancer risk factors among Saudi women) by Alsolami, Fatmah J, Azzeh, Firas S, Ghafouri, Khloud J, Ghaith, Mazen M, Almaimani, Riyad A, Almasmoum, Hussain A, Abdulal, Rwaa H, Abdulaal, Wesam H, Jazar, Abdelelah S, Tashtoush, Sufyan H

“…There are various factors that play a major role in influencing the overall health conditions of women diagnosed with breast cancer. The population of women in…”
Get full text

An Update on the Association of Protein Kinases with Cardiovascular Diseases by Amin, Fakhra, Ahmed, Azaj, Feroz, Anna, Khaki, Peerzada Shariq Shaheen, Khan, Mohd Shahnwaz, Tabrez, Shams, Zaidi, Syed Kashif, Abdulaal, Wesam H, Shamsi, Anas, Khan, Wajihullah, Bano, Bilqees

“…Protein kinases are the enzymes involved in phosphorylation of different proteins which leads to functional changes in those proteins. They belong to…”
Get more information

Scorpion Venom-Functionalized Quercetin Phytosomes for Breast Cancer Management: In Vitro Response Surface Optimization and Anticancer Activity against MCF-7 Cells by Alhakamy, Nabil A, Fahmy, Usama A, Eldin, Shaimaa M Badr, Ahmed, Osama A A, Aldawsari, Hibah M, Okbazghi, Solomon Z, Alfaleh, Mohamed A, Abdulaal, Wesam H, Alamoudi, Abdulmohsin J, Mady, Fatma M

“…Breast cancer is a dangerous type of cancer in women. Quercetin (QRT), a naturally occurring flavonoid, has wide biological effects including antioxidant,…”
Get full text

Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition by Abdulaal, Wesam H, Asfour, Hani Z, Helmi, Nawal, Al Sadoun, Hadeel, Eldakhakhny, Basmah, Alhakamy, Nabil A, Alqarni, Hani Mohammed, Alzahrani, Saeed Ali Mohammed, El-Moselhy, Mohamed A, Sharkawi, Sara S, Aboubakr, Esam Mohamed

“…Bleomycin is an effective antibiotic with a significant anticancer properties, but its use is limited due to its potential to induce dose-dependent pulmonary…”
Get full text

Fabrication, assessment, and optimization of alendronate sodium nanoemulsion-based injectable in-situ gel formulation for management of osteoporosis by Abdulaal, Wesam H., Hosny, Khaled M., Alhakamy, Nabil A., Bakhaidar, Rana B., Almuhanna, Yasir, Sabei, Fahad Y., Alissa, Mohammed, Majrashi, Mohammed, Alamoudi, Jawaher Abdullah, Hazzazi, Mohannad S., Jafer, Ayman, Khallaf, Rasha A.

“…Low bone mass, degeneration of bone tissue, and disruption of bone microarchitecture are all symptoms of the disease osteoporosis, which can decrease bone…”
Get full text

Urolithins Attenuate Multiple Symptoms of Obesity in Rats Fed on a High-Fat Diet by Abdulrahman, Abdulrasheed O, Kuerban, Abudukadeer, Alshehri, Zuhair Ahmed, Abdulaal, Wesam H, Khan, Jalaluddin Awlia, Khan, Mohammad Imran

“…Urolithins are gut microbiota-derived polyphenol metabolites, produced following the consumption of pomegranate, berries, and nuts. Recent studies have shown…”
Get full text

Elevated Levels of IL-33, IL-17 and IL-25 Indicate the Progression from Chronicity to Hepatocellular Carcinoma in Hepatitis C Virus Patients by Askoura, Momen, Abbas, Hisham A, Al Sadoun, Hadeel, Abdulaal, Wesam H, Abu Lila, Amr S, Almansour, Khaled, Alshammari, Farhan, Khafagy, El-Sayed, Ibrahim, Tarek S, Hegazy, Wael A H

“…Hepatitis C virus (HCV) is one of the most epidemic viral infections in the world. Three-quarters of individuals infected with HCV become chronic. As a…”
Get full text

Evaluation in broilers of aerosolized nanoparticles vaccine encapsulating imuno-stimulant and antigens of avian influenza virus/Mycoplasma gallisepticum by Kumosani, Taha, Yaghmoor, Soonham, Abdulaal, Wesam H, Barbour, Elie

“…The global prevalence of economic primary infection of poultry by H9N2 virus, including the Lineage A, panzootic group ME1, and associated with secondary…”
Get full text

In Silico-Based Discovery of Natural Anthraquinones with Potential against Multidrug-Resistant E. coli by Alhadrami, Hani A, Abdulaal, Wesam H, Hassan, Hossam M, Alhakamy, Nabil A, Sayed, Ahmed M

“…is a Gram-negative bacterium that causes different human infections. Additionally, it resists common antibiotics due to its outer protective membrane. Natural…”
Get full text

Repurposing Anti-diabetic Drugs to Cripple Quorum Sensing in Pseudomonas aeruginosa by Hegazy, Wael A. H., Khayat, Maan T., Ibrahim, Tarek S., Nassar, Majed S., Bakhrebah, Muhammed A., Abdulaal, Wesam H., Alhakamy, Nabil A., Bendary, Mahmoud M.

“…Pseudomonas aeruginosa is a significant human pathogen, it possesses almost all of the known antimicrobial resistance mechanisms. Quorum sensing (QS) is an…”
Get full text

Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity by Alhakamy, Nabil A, Fahmy, Usama A, Ahmed, Osama A A, Caruso, Giuseppe, Caraci, Filippo, Asfour, Hani Z, Bakhrebah, Muhammed A, N Alomary, Mohammad, Abdulaal, Wesam H, Okbazghi, Solomon Z, Abdel-Naim, Ashraf B, Eid, Basma G, Aldawsari, Hibah M, Kurakula, Mallesh, Mohamed, Amir I

“…This work aimed at improving the targeting and cytotoxicity of simvastatin (SMV) against colon cancer cells. SMV was encapsulated in chitosan polymers,…”
Get full text

Synthetic SARS-CoV-2 Spike-Based DNA Vaccine Elicits Robust and Long-Lasting Th1 Humoral and Cellular Immunity in Mice by Alamri, Sawsan S, Alluhaybi, Khalid A, Alhabbab, Rowa Y, Basabrain, Mohammad, Algaissi, Abdullah, Almahboub, Sarah, Alfaleh, Mohamed A, Abujamel, Turki S, Abdulaal, Wesam H, ElAssouli, M-Zaki, Alharbi, Rahaf H, Hassanain, Mazen, Hashem, Anwar M

“…The ongoing global pandemic of coronavirus disease 2019 (COVID-19) calls for an urgent development of effective and safe prophylactic and therapeutic measures…”
Get full text

Targeting allosteric sites of human aromatase: a comprehensive in-silico and in-vitro workflow to find potential plant-based anti-breast cancer therapeutics by Alhadrami, Hani A., Sayed, Ahmed M., Melebari, Sami A., Khogeer, Asem A., Abdulaal, Wesam H., Al-Fageeh, Mohamed B., Algahtani, Mohammad, Rateb, Mostafa E.

“…Recent findings suggested several allosteric pockets on human aromatase that could be utilised for the development of new modulators able to inhibit this…”
Get full text

Ceftriaxone and Melittin Synergistically Promote Wound Healing in Diabetic Rats by Alhakamy, Nabil A, Caruso, Giuseppe, Eid, Basma G, Fahmy, Usama A, Ahmed, Osama A A, Abdel-Naim, Ashraf B, Alamoudi, Abdulmohsin J, Alghamdi, Shareefa A, Al Sadoun, Hadeel, Eldakhakhny, Basmah M, Caraci, Filippo, Abdulaal, Wesam H

“…High glucose levels in diabetic patients are implicated in delay wound healing that could lead to more serious clinical complications. The aim of the present…”
Get full text

Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae by Abdulaal, Wesam H, Alhakamy, Nabil A, Asseri, Amer H, Radwan, Mohamed F, Ibrahim, Tarek S, Okbazghi, Solomon Z, Abbas, Hisham A, Mansour, Basem, Shoun, Aly A, Hegazy, Wael A H, Abdel-Halim, Mahmoud Saad

“…The development of resistance to carbapenems in due to the production of metallo-β-lactamases (MBLs) is a critical public health problem because carbapenems…”
Get full text