Search Results - "Werth, Kathrin"
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Solvent recovery and deacidification by organic solvent nanofiltration: Experimental investigation and mass transfer modeling
Published in Journal of membrane science (01-04-2017)Get full text
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2
Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance
Published in Nature communications (28-02-2020)“…Little is known regarding lymph node (LN)-homing of immune cells via afferent lymphatics. Here, we show, using a photo-convertible Dendra-2 reporter, that…”
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The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes
Published in Nature immunology (01-07-2014)“…Antigen-bearing dendritic cells transit through the lymphatics via chemokine receptor CCR7–dependent chemotactic cues. Rot and colleagues show that the…”
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Expression of ACKR4 demarcates the “peri-marginal sinus,” a specialized vascular compartment of the splenic red pulp
Published in Cell reports (Cambridge) (13-07-2021)“…The spleen comprises defined microanatomical compartments that uniquely contribute to its diverse host defense functions. Here, we identify a vascular…”
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CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo
Published in Frontiers in immunology (28-08-2018)“…To present antigens to cognate T cells, dendritic cells (DCs) exploit the chemokine receptor CCR7 to travel from peripheral tissue via afferent lymphatic…”
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The potential of organic solvent nanofiltration processes for oleochemical industry
Published in Separation and purification technology (12-07-2017)“…•Successful development of process model for membrane cascade design.•OSN enables significant energy savings in solvent recovery.•Efficient deacidification of…”
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Chemokines and other mediators in the development and functional organization of lymph nodes
Published in Immunological reviews (01-05-2019)“…Summary Secondary lymphoid organs like lymph nodes (LNs) are the main inductive sites for adaptive immune responses. Lymphocytes are constantly entering LNs,…”
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Hybrid separations combining distillation and organic solvent nanofiltration for separation of wide boiling mixtures
Published in Chemical engineering research & design (01-11-2014)“…•Design method for hybrid separations combining nanofiltration and distillation.•Optimisation under uncertainty with multi-objective optimization…”
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B cell hyperactivation in an Ackr4‐deficient mouse strain is not caused by lack of ACKR4 expression
Published in Journal of leukocyte biology (01-06-2020)“…The majority of genetically modified C57BL/6 mice contain congenic passenger DNA around the targeted gene locus as they were generated from 129‐derived…”
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In Vivo Killing Capacity of Cytotoxic T Cells Is Limited and Involves Dynamic Interactions and T Cell Cooperativity
Published in Immunity (Cambridge, Mass.) (16-02-2016)“…According to in vitro assays, T cells are thought to kill rapidly and efficiently, but the efficacy and dynamics of cytotoxic T lymphocyte (CTL)-mediated…”
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Active Shaping of Chemokine Gradients by Atypical Chemokine Receptors: A 4D Live-Cell Imaging Migration Assay
Published in Methods in enzymology (01-01-2016)“…Diffusion of chemokines away from their site of production results in the passive formation of chemokine gradients. We have recently shown that chemokine…”
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Biodiesel production from waste cooking oils through esterification: Catalyst screening, chemical equilibrium and reaction kinetics
Published in Chemical engineering research & design (01-03-2016)“…•Acid catalysed esterification enables biodiesel production from waste cooking oils.•Sulphuric acid identified as promising homogeneous catalyst for…”
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13
A 4-midable Connection: CCR7 Tetramers Link GPCR to Src Kinase Signaling
Published in Immunity (Cambridge, Mass.) (19-01-2016)“…Chemokine receptors are known to signal through heterotrimeric G proteins. In this issue, Hauser et al. (2016) report that inflammatory cues can induce…”
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CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability
Published in The Journal of clinical investigation (01-04-2016)“…Lymphatic collecting vessels direct lymph into and from lymph nodes (LNs) and can become hyperpermeable as the result of a previous infection. Enhanced…”
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15
Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses
Published in Cell reports (Cambridge) (22-06-2021)“…Immunosuppressive myeloid cells are frequently induced in tumors and attenuate anti-tumor effector functions. In this study, we differentiate immunosuppressive…”
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A systematic investigation of microwave-assisted reactive distillation: Influence of microwaves on separation and reaction
Published in Chemical engineering and processing (01-07-2015)“…•Microwave-assisted evaporation leads to superheating of liquids.•Microwaves do not enhance the separation efficiency in distillation.•The performance of…”
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Computer-aided process analysis of an integrated biodiesel process incorporating reactive distillation and organic solvent nanofiltration
Published in Computer Aided Chemical Engineering (2015)“…To enable the use of alternative cheap feedstock in the production of biodiesel, such as waste cooking oils, the contained free fatty acids have to be…”
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Book Chapter -
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CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability
Published in The Journal of clinical investigation (01-04-2016)“…Lymphatic collecting vessels direct lymph into and from lymph nodes (LNs) and can become hyperpermeable as the result of a previous infection. Enhanced…”
Get full text
Journal Article -
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CCR7 and IRF4-dependent dendritic cells regulate lymphatic collecting vessel permeability
Published in The Journal of clinical investigation (01-04-2016)“…Lymphatic collecting vessels direct lymph into and from lymph nodes (LNs) and can become hyperpermeable as the result of a previous infection. Enhanced…”
Get full text
Journal Article