Search Results - "Wernyj, Roman P."

Crucial Roles of Sp1 and Epigenetic Modifications in the Regulation of the CLDN4 Promoter in Ovarian Cancer Cells by Honda, Hiroshi, Pazin, Michael J., Ji, Hongxiu, Wernyj, Roman P., Morin, Patrice J.

“…Claudins form a large family of tight junction proteins that have essential roles in the control of paracellular ion flux and the maintenance of cell polarity…”
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Characterization of novel human ovarian cancer-specific transcripts (HOSTs) identified by serial analysis of gene expression by RANGEL, Leticia B. A, SHERMAN-BAUST, Cheryl A, WERNYJ, Roman P, SCHWARTZ, Donald R, CHO, Kathleen R, MORIN, Patrice J

“…A better understanding of changes in gene expression during ovarian tumorigenesis and the identification of specific tumor markers may lead to novel strategies…”
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Identification of function for CD44 intracytoplasmic domain (CD44-ICD): modulation of matrix metalloproteinase 9 (MMP-9) transcription via novel promoter response element by Miletti-González, Karl E, Murphy, Kyle, Kumaran, Muthu N, Ravindranath, Abhilash K, Wernyj, Roman P, Kaur, Swayamjot, Miles, Gregory D, Lim, Elaine, Chan, Rigel, Chekmareva, Marina, Heller, Debra S, Foran, David, Chen, Wenjin, Reiss, Michael, Bandera, Elisa V, Scotto, Kathleen, Rodríguez-Rodríguez, Lorna

“…CD44 is a multifunctional cell receptor that conveys a cancer phenotype, regulates macrophage inflammatory gene expression and vascular gene activation in…”
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CD44 promotes multi-drug resistance by protecting P-glycoprotein from FBXO21-mediated ubiquitination by Ravindranath, Abhilash K, Kaur, Swayamjot, Wernyj, Roman P, Kumaran, Muthu N, Miletti-Gonzalez, Karl E, Chan, Rigel, Lim, Elaine, Madura, Kiran, Rodriguez-Rodriguez, Lorna

“…Here we demonstrate that a ubiquitin E3-ligase, FBXO21, targets the multidrug resistance transporter, ABCB1, also known as P-glycoprotein (P-gp), for…”
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Molecular mechanisms of platinum resistance: still searching for the Achilles’ heel by Wernyj, Roman P., Morin, Patrice J.

“…The platinum compounds cisplatin and carboplatin are commonly used in cancer chemotherapy. However, tumors frequently develop resistance to these compounds,…”
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Identification of Function for CD44 Intracytoplasmic Domain (CD44-ICD) by Miletti-González, Karl E., Murphy, Kyle, Kumaran, Muthu N., Ravindranath, Abhilash K., Wernyj, Roman P., Kaur, Swayamjot, Miles, Gregory D., Lim, Elaine, Chan, Rigel, Chekmareva, Marina, Heller, Debra S., Foran, David, Chen, Wenjin, Reiss, Michael, Bandera, Elisa V., Scotto, Kathleen, Rodríguez-Rodríguez, Lorna

“…CD44 is a multifunctional cell receptor that conveys a cancer phenotype, regulates macrophage inflammatory gene expression and vascular gene activation in…”
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Modulation of specific protein expression levels by PTEN: identification of AKAP121, DHFR, G3BP, Rap1, and RCC1 as potential targets of PTEN by YANPING HUANG, WERNYJ, Roman P, NORTON, Darrell D, PRECHT, Patricia, SEMINARIO, Maria-Cristina, WANGE, Ronald L

“…The tumor suppressor PTEN is mutated in a high percentage of human cancers, and is implicated in pathways regulating cell growth, proliferation, survival, and…”
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Genomic mechanisms involved in the pleiotropic actions of 1,25-dihydroxyvitamin D3 by Christakos, S, Raval-Pandya, M, Wernyj, R P, Yang, W

“…The biologically active metabolite of vitamin D (cholecalciferol), i.e. 1,25-dihydroxyvitamin D3 [1,25(OH)2D3], is a secosteroid hormone whose mode of action…”
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Expression of calbindin-D 28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid β-peptide by Wernyj, Roman P, Mattson, Mark P, Christakos, Sylvia

“…The calcium binding protein, calbindin-D 28k is normally present in neurons. Recently we reported that brain injury and tumor necrosis factors (TNFs) induce…”
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Expression of calbindin-D28k in C6 glial cells stabilizes intracellular calcium levels and protects against apoptosis induced by calcium ionophore and amyloid β-peptide by WERNYJ, R. P, MATTSON, M. P, CHRISTAKOS, S

“…The calcium binding protein, calbindin-D28k is normally present in neurons. Recently we reported that brain injury and tumor necrosis factors (TNFs) induce…”
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Multiple antibodies to titin immunoreact with AHNAK and localize to the mitotic spindle machinery by Wernyj, Roman P., Ewing, Charles M., Isaacs, William B.

“…Recently, the large filamentous striated‐muscle protein titin has been observed in non‐muscle cells, and, in one instance, has been proposed to have a nuclear…”
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