Search Results - "Wernicke, Catrin"

Qualitätsmanagement in der RT-qPCR by Wernicke, Catrin, Franke, Philipp, Radke, Lars, Berge, Stephan, Frohme, Marcus

Get full text

Long-Term Ethanol Exposure Impairs Neuronal Differentiation of Human Neuroblastoma Cells Involving Neurotrophin-Mediated Intracellular Signaling and in Particular Protein Kinase C by Hellmann, Julian, Rommelspacher, Hans, Wernicke, Catrin

“…Background:  Revealing the molecular changes in chronic ethanol‐impaired neuronal differentiation may be of great importance for understanding ethanol‐related…”
Get full text

Numerical aberrations of chromosomes 1, 2, and 7 in astrocytomas studied by interphase cytogenetics by Wernicke, Catrin, Thiel, Gundula, Lozanova, Tanka, Vogel, Siegfried, Witkowski, Regine

“…For both juvenile astrocytomas and astrocytomas of adults, numerical and structural aberrations of chromosomes 1 and 7 have been described. To study the…”
Get full text

Raf kinase inhibitor protein enhances neuronal differentiation in human SH-SY5Y cells by Hellmann, Julian, Rommelspacher, Hans, Mühlbauer, Eckhard, Wernicke, Catrin

“…Neuronal differentiation has evolved as an essential process even in the adult brain, once disturbed being associated with the pathogenesis of several…”
Get more information

GENOMIC STRUCTURE AND CHROMOSOMAL LOCALIZATION OF THE HUMAN INTERLEUKIN 15 GENE (IL–15) by Krause, Hans, Jandrig, Burkhard, Wernicke, Catrin, Bulfone-Paus, Silvia, Pohl, Thomas, Diamantstein, Tibor

“…Interleukin 15 (IL–15) is a novel cytokine whose biological activities are similar to those of interleukin 2 (IL–2). The genomic sequence of human IL–15 has…”
Get full text

Association of the dopamine D2 receptor gene with alcohol dependence: haplotypes and subgroups of alcoholics as key factors for understanding receptor function by Kraschewski, Adrian, Reese, Jörn, Anghelescu, Ion, Winterer, Georg, Schmidt, Lutz G, Gallinat, Jürgen, Finckh, Ulrich, Rommelspacher, Hans, Wernicke, Catrin

“…OBJECTIVESThe dopamine D2 receptor (DRD2) plays an important role in the reinforcing and motivating effects of ethanol. Several polymorphisms have been…”
Get full text

9-Methyl-β-carboline up-regulates the appearance of differentiated dopaminergic neurones in primary mesencephalic culture by Hamann, Juliane, Wernicke, Catrin, Lehmann, Jochen, Reichmann, Heinz, Rommelspacher, Hans, Gille, Gabriele

“…β-Carbolines (BCs) derive from tryptophan and its derivatives. They are formed endogenously in humans and mammals and occur inter alia in cooked meat and…”
Get full text

Chronic ethanol exposure changes dopamine D2 receptor splicing during retinoic acid-induced differentiation of human SH-SY5Y cells by Wernicke, Catrin, Hellmann, Julian, Finckh, Ulrich, Rommelspacher, Hans

“…There is evidence for ethanol-induced impairment of the dopaminergic system in the brain during development. The dopamine D2 receptor (DRD2) and the dopamine…”
Get full text

9-Methyl-β-carboline has restorative effects in an animal model of Parkinson’s disease by Wernicke, Catrin, Hellmann, Julian, Zięba, Barbara, Kuter, Katarzyna, Ossowska, Krystyna, Frenzel, Monika, Dencher, Norbert A., Rommelspacher, Hans

“…In a previous study, a primary culture of midbrain cells was exposed to 9-methyl-β-carboline for 48h, which caused an increase in the number of tyrosine…”
Get full text

Cytotoxicity of β-carbolines in dopamine transporter expressing cells: Structure–activity relationships by Wernicke, Catrin, Schott, Yvonne, Enzensperger, Christoph, Schulze, Gert, Lehmann, Jochen, Rommelspacher, Hans

“…Some β-carbolines (BC) are natural constituents in the human brain deriving from tryptophan, tryptamine, and serotonin. In vitro and animal experiments suggest…”
Get full text

RefPrimeCouch--a reference gene primer CouchApp by Silbermann, Jascha, Wernicke, Catrin, Pospisil, Heike, Frohme, Marcus

“…To support a quantitative real-time polymerase chain reaction standardization project, a new reference gene database application was required. The new database…”
Get full text

Haplotypes of dopamine and serotonin transporter genes are associated with antisocial personality disorder in alcoholics by Reese, Jörn, Kraschewski, Adrian, Anghelescu, Ion, Winterer, Georg, Schmidt, Lutz G, Gallinat, Jürgen, Rüschendorf, Franz, Rommelspacher, Hans, Wernicke, Catrin

“…A different genetic background is postulated for alcoholics with early onset and with antisocial personality disorder (type 2 alcoholics) compared with those…”
Get full text

Polymorphisms in the N-methyl-D-aspartate receptor 1 and 2B subunits are associated with alcoholism-related traits by Wernicke, Catrin, Samochowiec, Jerzy, Schmidt, Lutz G, Winterer, Georg, Smolka, Michael, Kucharska-Mazur, Jolanta, Horodnicki, Jan, Gallinat, Jürgen, Rommelspacher, Hans

“…This study examined the hypothesis that allelic variants of the ionotropic glutamatergic N-methyl-D-aspartate receptor (NMDAR) are associated with…”
Get full text

Serotonin transporter promoter polymorphism and dopaminergic sensitivity in alcoholics by Budde, Henning, Sander, Thomas, Wernicke, Catrin, Müller, Anett, Gallinat, Jürgen, Schmidt, Lutz G., Smolka, Michael N.

“…The central serotonin (5-HT) system plays an important role in the rewarding and addictive properties of alcohol by a direct activation of the mesolimbic…”
Get full text

Allelic Variants of the Functional Promoter Polymorphism of the Human Serotonin Transporter Gene is Associated with Auditory Cortical Stimulus Processing by GALLINAT, Jürgen, SENKOWSKI, Daniel, HERRMANN, Werner M, WERNICKE, Catrin, JUCKEL, Georg, BECKER, Isabell, SANDER, Thomas, SMOLKA, Michael, HEGERL, Ulrich, ROMMELSPACHER, Hans, WINTERER, Georg

“…The loudness dependence (LD) of the auditory-evoked N1/P2 component has been shown to be related to the central serotonergic neurotransmission. Allelic…”
Get full text

Association of human hippocampal neurochemistry, serotonin transporter genetic variation, and anxiety by Gallinat, Jürgen, Ströhle, Andreas, Lang, Undine E., Bajbouj, Malek, Kalus, Peter, Montag, Christiane, Seifert, Frank, Wernicke, Catrin, Rommelspacher, Hans, Rinneberg, Herbert, Schubert, Florian

“…The impact of the serotonin transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR) on anxiety-related behavior and related cerebral activation has…”
Get full text

Evidence for the importance of the human dopamine transporter gene for withdrawal symptomatology of alcoholics in a German population by Wernicke, Catrin, Smolka, Michael, Gallinat, Jürgen, Winterer, Georg, Schmidt, Lutz G., Rommelspacher, Hans

“…Two new polymorphisms in the 3′ untranslated region (3′UTR) of the dopamine transporter (DAT1) gene, adjacent to the known variable number of tandem repeats…”
Get full text

Parkinsonʼs disease-like syndrome in rats induced by 2,9-dimethyl-β-carbolinium ion, a β-carboline occurring in the human brain by Lorenc-Koci, Elżbieta, Rommelspacher, Hans, Schulze, Gert, Wernicke, Catrin, Kuter, Katarzyna, Śmiałowska, Maria, Wierońska, Joana, Zięba, Barbara, Ossowska, Krystyna

“…Regarding the pathogenesis of Parkinsonʼs disease, a neurotoxin hypothesis was proposed following the discovery that…”
Get full text

No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits by Lang, Undine E, Bajbouj, Malek, Wernicke, Catrin, Rommelspacher, Hans, Danker-Hopfe, Heidi, Gallinat, Jürgen

“…Serotonergic neurotransmission, which is involved in many psychiatric disorders, is mediated by the serotonin transporter protein. Gene coding for the…”
Get more information

Norepinephrine transporter gene polymorphism is not associated with susceptibility to alcohol dependence by Samochowiec, Jerzy, Kucharska–Mazur, Jolanta, Kaminski, Ryszard, Smolka, Michael, Rommelschpacher, Hans, Wernicke, Catrin, Tymicz, Agnieszka, Schmidt, Lutz Gerhardt

“…Abnormalities in monoamine neurotransmission have been implicated in the pathogenesis of alcoholism, mood disorders and schizophrenia. Murine norepinephrine…”
Get full text