Search Results - "Wernick, I"

Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons by Virdi, Gurvir S., Choi, Minee L., Evans, James R., Yao, Zhi, Athauda, Dilan, Strohbuecker, Stephanie, Nirujogi, Raja S., Wernick, Anna I., Pelegrina-Hidalgo, Noelia, Leighton, Craig, Saleeb, Rebecca S., Kopach, Olga, Alrashidi, Haya, Melandri, Daniela, Perez-Lloret, Jimena, Angelova, Plamena R., Sylantyev, Sergiy, Eaton, Simon, Heales, Simon, Rusakov, Dmitri A., Alessi, Dario R., Kunath, Tilo, Horrocks, Mathew H., Abramov, Andrey Y., Patani, Rickie, Gandhi, Sonia

“…Mutations in the SNCA gene cause autosomal dominant Parkinson’s disease (PD), with loss of dopaminergic neurons in the substantia nigra, and aggregation of…”
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Multiple system atrophy and apolipoprotein E by Ogaki, Kotaro, Martens, Yuka A., Heckman, Michael G., Koga, Shunsuke, Labbé, Catherine, Lorenzo‐Betancor, Oswaldo, Wernick, Anna I., Walton, Ronald L., Soto, Alexandra I., Vargas, Emily R., Nielsen, Henrietta M., Fujioka, Shinsuke, Kanekiyo, Takahisa, Uitti, Ryan J., van Gerpen, Jay A., Cheshire, William P., Wszolek, Zbigniew K., Low, Phillip A., Singer, Wolfgang, Dickson, Dennis W., Bu, Guojun, Ross, Owen A.

“…ABSTRACT Background: Dysregulation of the specialized lipid metabolism involved in myelin synthesis and maintenance by oligodendrocytes has been associated…”
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MECR Mutations Cause Childhood-Onset Dystonia and Optic Atrophy, a Mitochondrial Fatty Acid Synthesis Disorder by Heimer, Gali, Kerätär, Juha M., Riley, Lisa G., Balasubramaniam, Shanti, Eyal, Eran, Pietikäinen, Laura P., Hiltunen, J. Kalervo, Marek-Yagel, Dina, Hamada, Jeffrey, Gregory, Allison, Rogers, Caleb, Hogarth, Penelope, Nance, Martha A., Shalva, Nechama, Veber, Alvit, Tzadok, Michal, Nissenkorn, Andreea, Tonduti, Davide, Renaldo, Florence, Bamshad, Michael J., Leal, Suzanne M., Nickerson, Deborah A., Anderson, Peter, Annable, Marcus, Blue, Elizabeth Marchani, Buckingham, Kati J., Chin, Jennifer, Chong, Jessica X., Cornejo, Rodolfo, Davis, Colleen P., Frazar, Christopher, He, Zongxiao, Jarvik, Gail P., Jimenez, Guillaume, Johanson, Eric, Kolar, Tom, Krauter, Stephanie A., Luksic, Daniel, Marvin, Colby T., McGee, Sean, McGoldrick, Daniel J., Patterson, Karynne, Perez, Marcos, Phillips, Sam W., Pijoan, Jessica, Robertson, Peggy D., Santos-Cortez, Regie, Shankar, Aditi, Slattery, Krystal, Shively, Kathryn M., Siegel, Deborah L., Smith, Joshua D., Tackett, Monica, Wang, Gao, Wegener, Marc, Weiss, Jeffrey M., Wernick, Riana I., Wheeler, Marsha M., Yi, Qian, Kraoua, Ichraf, Panteghini, Celeste, Valletta, Lorella, Garavaglia, Barbara, Cowley, Mark J., Gayevskiy, Velimir, Roscioli, Tony, Silberstein, Jonathon M., Hoffmann, Chen, Raas-Rothschild, Annick, Tiranti, Valeria, Anikster, Yair, Christodoulou, John, Kastaniotis, Alexander J., Ben-Zeev, Bruria, Hayflick, Susan J.

“…Mitochondrial fatty acid synthesis (mtFAS) is an evolutionarily conserved pathway essential for the function of the respiratory chain and several mitochondrial…”
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Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity by Choi, Minee L., Chappard, Alexandre, Singh, Bhanu P., Maclachlan, Catherine, Rodrigues, Margarida, Fedotova, Evgeniya I., Berezhnov, Alexey V., De, Suman, Peddie, Christopher J., Athauda, Dilan, Virdi, Gurvir S., Zhang, Weijia, Evans, James R., Wernick, Anna I., Zanjani, Zeinab Shadman, Angelova, Plamena R., Esteras, Noemi, Vinokurov, Andrey Y., Morris, Katie, Jeacock, Kiani, Tosatto, Laura, Little, Daniel, Gissen, Paul, Clarke, David J., Kunath, Tilo, Collinson, Lucy, Klenerman, David, Abramov, Andrey Y., Horrocks, Mathew H., Gandhi, Sonia

“…Aggregation of alpha-synuclein (α-Syn) drives Parkinson’s disease (PD), although the initial stages of self-assembly and structural conversion have not been…”
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Consequences of Differing MR and CT Contouring of the Prostate Base and Apex and Implications for Brachytherapy Post-implant Analysis by Maletz, K, Ennis, R, Wernick, I

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Increased Consistency and Time Savings for Delineation of Pelvic Lymph Nodes for Adjuvant Therapy of Endometrial Cancer by Ennis, R.D, Young, A.V, Wernick, I, Evans, A

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Declines in PSA Velocity below Threshold of 2 ng/ml/yr after Retesting by Wernick, I, Maletz, K, Ennis, R

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Clinicopathologic and genetic features of multiple system atrophy with Lewy body disease by Koga, Shunsuke, Li, Fuyao, Zhao, Na, Roemer, Shanu F., Ferman, Tanis J., Wernick, Anna I., Walton, Ronald L., Faroqi, Ayman H., Graff‐Radford, Neill R., Cheshire, William P., Ross, Owen A., Dickson, Dennis W.

“…Background: Abnormal aggregates of α‐synuclein are pathologic hallmarks of multiple system atrophy (MSA) and Lewy body disease (LBD). LBD sometimes coexists…”
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Sex and Mitonuclear Adaptation in Experimental Caenorhabditis elegans Populations by Wernick, Riana I, Christy, Stephen F, Howe, Dana K, Sullins, Jennifer A, Ramirez, Joseph F, Sare, Maura, Penley, McKenna J, Morran, Levi T, Denver, Dee R, Estes, Suzanne

“…To reveal phenotypic and functional genomic patterns of mitonuclear adaptation, a laboratory adaptation study with nematodes was conducted in which…”
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GBA variation and susceptibility to multiple system atrophy by Wernick, Anna I., Walton, Ronald L., Koga, Shunsuke, Soto-Beasley, Alexandra I., Heckman, Michael G., Gan-Or, Ziv, Ren, Yingxue, Rademakers, Rosa, Uitti, Ryan J., Wszolek, Zbigniew K., Cheshire, William P., Dickson, Dennis W., Ross, Owen A.

“…Genetic variants in the glucocerebrosidase (GBA) gene have been previously associated with susceptibility to synucleinopathies. The risk is well-established in…”
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Author Correction: Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity by Choi, Minee L., Chappard, Alexandre, Singh, Bhanu P., Maclachlan, Catherine, Rodrigues, Margarida, Fedotova, Evgeniya I., Berezhnov, Alexey V., De, Suman, Peddie, Christopher J., Athauda, Dilan, Virdi, Gurvir S., Zhang, Weijia, Evans, James R., Wernick, Anna I., Zanjani, Zeinab Shadman, Angelova, Plamena R., Esteras, Noemi, Vinokurov, Andrey Y., Morris, Katie, Jeacock, Kiani, Tosatto, Laura, Little, Daniel, Gissen, Paul, Clarke, David J., Kunath, Tilo, Collinson, Lucy, Klenerman, David, Abramov, Andrey Y., Horrocks, Mathew H., Gandhi, Sonia

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Modeling materials flow of waste concrete from construction and demolition wastes in Taiwan by Hsiao, T.Y., Huang, Y.T., Yu, Y.H., Wernick, I.K.

“…Material flows of concrete from construction and demolition (C&D) waste in Taiwan have grown considerably over the last two decades, Hsiao et al. (2001). This…”
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Investigating ELOVL7 coding variants in multiple system atrophy by Wernick, Anna I., Walton, Ronald L., Soto-Beasley, Alexandra I., Koga, Shunsuke, Ren, Yingxue, Heckman, Michael G., Milanowski, Lukasz M., Valentino, Rebecca R., Kondru, Naveen, Uitti, Ryan J., Cheshire, William P., Wszolek, Zbigniew K., Dickson, Dennis W., Ross, Owen A.

“…•Genome-wide association studies have implicated ELOVL7 variation in MSA risk.•Exonic screening of coding variants in MSA and control subjects for coding…”
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Frequency of spinocerebellar ataxia mutations in patients with multiple system atrophy by Wernick, Anna I., Walton, Ronald L., Soto-Beasley, Alexandra I., Koga, Shunsuke, Heckman, Michael G., Valentino, Rebecca R., Milanowski, Lukasz M., Hoffman-Zacharska, Dorota, Koziorowski, Dariusz, Hassan, Anhar, Uitti, Ryan J., Cheshire, William P., Singer, Wolfgang, Wszolek, Zbigniew K., Dickson, Dennis W., Low, Phillip A., Ross, Owen A.

“…Purpose Investigate single nucleotide variants and short tandem repeats in 39 genes related to spinocerebellar ataxia in clinical and pathologically defined…”
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Paths of Heritable Mitochondrial DNA Mutation and Heteroplasmy in Reference and gas-1 Strains of Caenorhabditis elegans by Wernick, Riana I, Estes, Suzanne, Howe, Dana K, Denver, Dee R

“…Heteroplasmy-the presence of more than one mitochondrial DNA (mtDNA) sequence type in a cell, tissue, or individual-impacts human mitochondrial disease and…”
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The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1 by Gustavsson, Emil K, Sethi, Siddharth, Gao, Yujing, Brenton, Jonathan W, García-Ruiz, Sonia, Zhang, David, Garza, Raquel, Reynolds, Regina H, Evans, James R, Chen, Zhongbo, Grant-Peters, Melissa, Macpherson, Hannah, Montgomery, Kylie, Dore, Rhys, Wernick, Anna I, Arber, Charles, Wray, Selina, Gandhi, Sonia, Esselborn, Julian, Blauwendraat, Cornelis, Douse, Christopher H, Adami, Anita, Atacho, Diahann A M, Kouli, Antonina, Quaegebeur, Annelies, Barker, Roger A, Englund, Elisabet, Platt, Frances, Jakobsson, Johan, Wood, Nicholas W, Houlden, Henry, Saini, Harpreet, Bento, Carla F, Hardy, John, Ryten, Mina

“…Mutations in cause Gaucher disease and are the most important genetic risk factor for Parkinson's disease. However, analysis of transcription at this locus is…”
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Adaptive Evolution under Extreme Genetic Drift in Oxidatively Stressed Caenorhabditis elegans by Christy, Stephen F, Wernick, Riana I, Lue, Michael J, Velasco, Griselda, Howe, Dana K, Denver, Dee R, Estes, Suzanne

“…Abstract A mutation-accumulation (MA) experiment with Caenorhabditis elegans nematodes was conducted in which replicate, independently evolving lines were…”
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Selfish Mitochondrial DNA Proliferates and Diversifies in Small, but not Large, Experimental Populations of Caenorhabditis briggsae by Phillips, Wendy S, Coleman-Hulbert, Anna L, Weiss, Emily S, Howe, Dana K, Ping, Sita, Wernick, Riana I, Estes, Suzanne, Denver, Dee R

“…Evolutionary interactions across levels of biological organization contribute to a variety of fundamental processes including genome evolution, reproductive…”
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Resource recovery from used rubber tires by Amari, Takeshi, Themelis, Nickolas J, Wernick, Iddo K

“…Including car, truck, bus, and airplane tires, 266 million tires were scrapped in the US in 1996 ( Scrap Tire Management Council (STMC), 1997.). More than…”
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THE FORESTER'S LEVER: INDUSTRIAL ECOLOGY & WOOD PRODUCTS by Wernick, Iddo K, Waggoner, Paul E, Ausubel, Jesse H

“…Abstract Despite increases in the nation's population, affluence, and timber removals, US forest area has remained constant and timber inventory has risen 30…”
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