Search Results - "Werner, R.G."

Refine Results
  1. 1

    Investigations on oxygen limitations of adherent cells growing on macroporous microcarriers by PREISSMANN, A, WIESMANN, R, BUCHHOLZ, R, WERNER, R. G, NOE, W

    Published in Cytotechnology (Dordrecht) (01-07-1997)
    “…Macroporous microcarriers are commonly applied to fixed and fluidized bed bioreactors for the cultivation of stringent adherent cells. Several investigations…”
    Get full text
    Journal Article
  2. 2

    Stability of luciferase plasmid entrapped in cationic bilayer vesicles by Manosroi, A., Thathang, K., Werner, R.G., Schubert, R., Manosroi, J.

    Published in International journal of pharmaceutics (22-05-2008)
    “…Characteristics and physical stability of luciferase plasmid (pLuc) entrapped in cationic bilayer vesicles prepared from various molar ratios of amphiphiles…”
    Get full text
    Journal Article
  3. 3

    Enrichment of [tryptophan] auxotrophic mutants in Streptomyces griseus [Fungi] by Werner, R.G, Demain, A.L

    Published in Applied and Environmental Microbiology (01-09-1980)
    “…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
    Get full text
    Journal Article
  4. 4

    p27Kip1-mediated controlled proliferation technology increases constitutive sICAM production in CHO-DUKX adapted for growth in suspension and serum-free media by Meents, Heiko, Enenkel, Barbara, Werner, Rolf G., Fussenegger, Martin

    Published in Biotechnology and bioengineering (20-09-2002)
    “…We have engineered dihydrofolate reductase‐deficient (dhfr−) Chinese hamster ovary (CHO)‐DUKX B11 cells adapted for growth in serum‐free suspension cultures…”
    Get full text
    Journal Article
  5. 5

    Validation and Quality Assurance: Risk and Potential of Process Changes by Rolf G. Werner

    Published in Chimia (01-10-1994)
    “…The development of biotechnical processes is a very complex operation. It involves the creation and verification of a strong expression system, selection and…”
    Get full text
    Journal Article
  6. 6

    Monitoring of intracellular ribonucleotide pools is a powerful tool in the development and characterization of mammalian cell culture processes by Grammatikos, Stefanos I., Tobien, Kai, Noé, Wolfgang, Werner, Rolf G.

    Published in Biotechnology and bioengineering (05-08-1999)
    “…Efficient cell culture process development for the industrial production of recombinant therapeutics is characterized by constraints which pertain to issues…”
    Get full text
    Journal Article
  7. 7

    Safety and economic aspects of continuous mammalian cell culture by Werner, R G, Walz, F, Noé, W, Konrad, A

    Published in Journal of biotechnology (01-01-1992)
    “…Mammalian cell cultures are the most appropriate host cells for recombinant DNA derived products if complex protein structures have to be synthesized in their…”
    Get more information
    Journal Article
  8. 8
  9. 9

    Validation and Quality Assurance: Risk and Potential of Process Changes by Rolf G. Werner

    Published in Chimia (01-10-1994)
    “…The development of biotechnical processes is a very complex operation. It involves the creation and verification of a strong expression system, selection and…”
    Get full text
    Journal Article
  10. 10
  11. 11

    Safe biotechnology (4). Recommendations for safety levels for biotechnological operations with microorganisms that cause diseases in plants by Frommer, W, Archer, L, Boon, B, Brunius, G, Collins, C H, Crooy, P, Donikian, R, Economidis, I, Frontali, C, Gaal, T

    Published in Applied microbiology and biotechnology (01-11-1992)
    “…The Working Party on Safety in Biotechnology of the European Federation of Biotechnology has proposed a classification of microorganisms that cause diseases in…”
    Get full text
    Journal Article
  12. 12

    Appropriate mammalian expression systems for biopharmaceuticals by Werner, R G, Noé, W, Kopp, K, Schlüter, M

    Published in Arzneimittel-Forschung (01-08-1998)
    “…Process development for biopharmaceuticals is dictated by product quality, drug safety and economy of the manufacturing process. Not surprisingly, these…”
    Get more information
    Journal Article
  13. 13

    Identification and development of new biopharmaceuticals by Werner, R G

    Published in Arzneimittel-Forschung (01-05-1998)
    “…The 34 protein based biopharmaceuticals which are presently on the market reached a total sale of 10 Mio $ in 1996. Out of 500 biopharmaceutical under…”
    Get more information
    Journal Article
  14. 14

    Innovative and economic potential of mammalian cell culture by Werner, R G

    Published in Arzneimittel-Forschung (01-04-1998)
    “…Innovations for economic optimization of manufacturing processes of mammalian cell culture processes address new expression systems, optimized cell culture…”
    Get more information
    Journal Article
  15. 15

    Flip chip packaging by Werner, R.G., Frear, D.R., DeRosa, J., Sorongon, E.

    “…Some of the needs for improved performance can be met with versions of the packaging solutions that have been developed over the last 5-10 years. These…”
    Get full text
    Conference Proceeding
  16. 16

    Mammalian cell cultures. Part II: Genetic engineering, protein glycosylation, fermentation and process control by Werner, R G, Noé, W

    Published in Arzneimittel-Forschung (01-11-1993)
    “…For expression of human genes in mammalian cell culture regulatory sequences such as promotor or terminator region of viral origin are required. The most…”
    Get more information
    Journal Article
  17. 17

    Mammalian cell cultures. Part I: Characterization, morphology and metabolism by Werner, R G, Noé, W

    Published in Arzneimittel-Forschung (01-10-1993)
    “…Primary cell cultures are obtained by trypsinization from tissue cultures usually as a monolayer culture. The absence of fetal calf serum will support…”
    Get more information
    Journal Article
  18. 18

    Monitoring the glycosylation pattern of recombinant interferon-omega with high-pH anion-exchange chromatography and capillary electrophoresis by Kopp, K, Schlüter, M, Werner, R G

    Published in Arzneimittel-Forschung (01-12-1996)
    “…The enzymatic glycosylation of certain asparagine residues in the protein structure has a profound influence on their physico-chemical properties. Many…”
    Get more information
    Journal Article
  19. 19

    Biobusiness in the pharmaceutical industry by Werner, R G

    Published in Arzneimittel-Forschung (01-09-1987)
    “…Although conventional biotechnology used for the synthesis of antibiotics, vitamins, amino acids, nucleotides, enzyme inhibitors and immunomodulating compounds…”
    Get more information
    Journal Article
  20. 20

    New biotechnology as a logical outgrowth of molecular biology by Werner, R G

    Published in Arzneimittel-Forschung (01-01-1986)
    “…Since the dawn of civilization biotechnical methods have been used to improve lifestyle by increasing the variety of food products and enriching their taste or…”
    Get more information
    Journal Article