Search Results - "Werner, M H"

The role of fat distribution and inflammation in the origin of endometrial cancer, study protocol of the ENDOCRINE study by van den Bosch, A. A. S, Pijnenborg, J. M. A, Romano, A, Haldorsen, I. S, Werner, H. M. J

“…Background Obesity is a growing problem worldwide, especially in countries with improved socioeconomic circumstances. Also, in the Netherlands the incidence of…”
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Current Status of Molecular Biomarkers in Endometrial Cancer by Werner, H. M. J., Salvesen, H. B.

“…In spite of the high and increasing incidence of endometrial cancer, our current models for prediction of prognosis and even more treatment response are…”
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Adjuvant Use of PlasmaJet Device During Cytoreductive Surgery for Advanced-Stage Ovarian Cancer: Results of the PlaComOv-study, a Randomized Controlled Trial in The Netherlands by Nieuwenhuyzen-de Boer, G. M., Hofhuis, W., Reesink-Peters, N., Willemsen, S., Boere, I. A., Schoots, I. G., Piek, J. M. J., Hofman, L. N., Beltman, J. J., van Driel, W. J., Werner, H. M. J., Baalbergen, A., van Haaften-de Jong, A. M. L. D., Dorman, M., Haans, L., Nedelcu, I., Ewing-Graham, P. C., van Beekhuizen, H. J.

“…Objective Standard surgical treatment of advanced-stage ovarian carcinoma with electrosurgery cannot always result in complete cytoreductive surgery (CRS),…”
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ASO Visual Abstract: The Role of Adjuvant Use of the PlasmaJet® Device During Cytoreductive Surgery for Advanced-Stage Ovarian Cancer—Results of the PlaComOv-Study, a Randomized, Controlled Trial in the Netherlands by Nieuwenhuyzen-de Boer, G. M., Hofhuis, W., Reesink-Peters, N., Willemsen, S., Boere, I. A., Schoots, I. G., Piek, J. M. J., Hofman, L. N., Beltman, J. J., van Driel, W. J., Werner, H. M. J., Baalbergen, A., van Haaften-de Jong, A. M. L. D., Dorman, M., Haans, L., Nedelcu, I., Ewing-Graham, P. C., van Beekhuizen, H. J.

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KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer by Birkeland, E, Wik, E, Mjøs, S, Hoivik, E A, Trovik, J, Werner, H M J, Kusonmano, K, Petersen, K, Raeder, M B, Holst, F, Øyan, A M, Kalland, K-H, Akslen, L A, Simon, R, Krakstad, C, Salvesen, H B

“…Background: Three quarter of endometrial carcinomas are treated at early stage. Still, 15 to 20% of these patients experience recurrence, with little effect…”
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Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas by Haldorsen, I S, Stefansson, I, Grüner, R, Husby, J A, Magnussen, I J, Werner, H M J, Salvesen, Ø O, Bjørge, L, Trovik, J, Taxt, T, Akslen, L A, Salvesen, H B

“…Background: We aimed to study the angiogenic profile based on histomorphological markers in endometrial carcinomas in relation to imaging parameters obtained…”
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A discordant histological risk classification in preoperative and operative biopsy in endometrial cancer is reflected in metastatic risk and prognosis by Werner, H.M.J, Trovik, J, Marcickiewicz, J, Tingulstad, S, Staff, A.C, Engh, M.E, Oddenes, K, Rokne, J.A, Tjugum, J, Lode, M.S, Amant, F, Salvesen, H.B

“…Abstract Introduction In endometrial cancer, tissue for histological evaluation is obtained preoperatively (endometrial biopsy) and operatively (hysterectomy…”
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ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO by LAUSEN, J, LIU, S, FLIEGAUF, M, LÜBBERT, M, WERNER, M. H

“…A 117 bp fragment of the human ELA2 promoter has been characterized that can act as a minimal promoter for the expression of neutrophil elastase. Chromatin…”
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Maintained survival outcome after reducing lymphadenectomy rates and optimizing adjuvant treatment in endometrial cancer by Forsse, D., Berg, H.F., Bozickovic, O., Engerud, H., Halle, M.K., Hoivik, E.A., Woie, K., Werner, H.M.J., Haldorsen, I.S., Trovik, J., Krakstad, C.

“…Main controversies in endometrial cancer treatment include the role of lymphadenectomy and optimal adjuvant treatment. We assessed clinical outcome in a…”
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Activation of the Sphingomyelin Cycle Through the Low-Affinity Neurotrophin Receptor by Dobrowsky, Rick T., Werner, Mark H., Castellino, Alexander M., Chao, Moses V., Hannun, Yusuf A.

“…The role of the low-affinity neurotrophin receptor (p75$^{NTR}$) in signal transduction is undefined. Nerve growth factor can activate the sphingomyelin cycle,…”
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Intercalation, DNA Kinking, and the Control of Transcription by Werner, Milton H., Gronenborn, Angela M., Clore, G. Marius

“…Biological processes involved in the control and regulation of transcription are dependent on protein-induced distortions in DNA structure that enhance the…”
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Harmonisation of biobanking standards in endometrial cancer research by Adishesh, M, Fyson, A, DeCruze, S B, Kirwan, J, Werner, H M J, Hapangama, D K

“…Background: Endometrial cancer is the most common gynaecological cancer and its incidence is predicted to escalate by 50–100% in 2025 with a parallel increase…”
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Revision of FIGO surgical staging in 2009 for endometrial cancer validates to improve risk stratification by Werner, H.M.J, Trovik, J, Marcickiewicz, J, Tingulstad, S, Staff, A.C, Amant, F, Salvesen, H.B

“…Abstract Objective Correct staging is a cornerstone in cancer treatment. The FIGO surgical staging for endometrial cancer was revised in 2009. We have…”
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Loss of GPER identifies new targets for therapy among a subgroup of ERα-positive endometrial cancer patients with poor outcome by Krakstad, C, Trovik, J, Wik, E, Engelsen, I B, Werner, H M J, Birkeland, E, Raeder, M B, Øyan, A M, Stefansson, I M, Kalland, K H, Akslen, L A, Salvesen, H B

“…Background: The G protein-coupled oestrogen receptor, GPER, has been suggested as an alternative oestrogen receptor. Our purpose was to investigate the…”
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DNA ploidy in curettage specimens identifies high-risk patients and lymph node metastasis in endometrial cancer by Njølstad, T S, Trovik, J, Hveem, T S, Kjæreng, M L, Kildal, W, Pradhan, M, Marcickiewicz, J, Tingulstad, S, Staff, A C, Haugland, H K, Eraker, R, Oddenes, K, Rokne, J A, Tjugum, J, Lode, M S, Amant, F, Werner, H M, Salvesen, H B, Danielsen, H E

“…Background: Preoperative risk stratification is essential in tailoring endometrial cancer treatment, and biomarkers predicting lymph node metastasis and…”
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The increasing incidence of malignant gliomas and primary central nervous system lymphoma in the elderly by Werner, M H, Phuphanich, S, Lyman, G H

“…Studies indicate that the incidence of primary malignant brain tumors in the elderly is increasing, but this may reflect increased case ascertainment due to…”
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Runt domains take the lead in hematopoiesis and osteogenesis by Werner, Milton H, Shigesada, Katsuya, Ito, Yoshiaki

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Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial–mesenchymal transition and PI3K alterations by Wik, E, Trovik, J, Kusonmano, K, Birkeland, E, Raeder, M.B, Pashtan, I, Hoivik, E.A, Krakstad, C, Werner, H.M.J, Holst, F, Mjøs, S, Halle, M.K, Mannelqvist, M, Mauland, K.K, Oyan, A.M, Stefansson, I.M, Petersen, K, Simon, R, Cherniack, A.D, Meyerson, M, Kalland, K.H, Akslen, L.A, Salvesen, H.B

“…Abstract Purpose Our previously reported 29-gene expression signature identified an aggressive subgroup of endometrial cancer patients with PI3K activation. We…”
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FADD self-association is required for stable interaction with an activated death receptor by Sandu, C, Morisawa, G, Wegorzewska, I, Huang, T, Arechiga, A F, Hill, J M, Kim, T, Walsh, C M, Werner, M H

“…Receptor-mediated programmed cell death proceeds through an activated receptor to which the death adaptor FADD and the initiator procaspases 8 and/or 10 are…”
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Localization of immunoreactive epidermal growth factor receptors in human nervous system by Werner, M H, Nanney, L B, Stoscheck, C M, King, L E

“…Epidermal growth factor is a well-defined peptide which stimulates cell growth and elicits cell responses in a variety of tissues by binding to specific…”
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