Search Results - "Werneck, Miriam B. F."

Identification of dendritic antigen-presenting cells in the zebrafish by Lugo-Villarino, Geanncarlo, Balla, Keir M., Stachura, David L., Bañuelos, Karina, Werneck, Miriam B. F., Traver, David, Glimcher, Laurie H.

“…In mammals, dendritic cells (DCs) form the key link between the innate and adaptive immune systems. DCs act as immune sentries in various tissues and, upon…”
Get full text

Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation by Fazolini, Narayana P B, Cruz, André L S, Werneck, Miriam B F, Viola, João P B, Maya-Monteiro, Clarissa M, Bozza, Patrícia T

“…Accumulating evidence suggests that obesity and enhanced inflammatory reactions are predisposing conditions for developing colon cancer. Obesity is associated…”
Get full text

T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease by Werneck, Miriam B. F, Lugo-Villarino, Geanncarlo, Hwang, Eun Sook, Cantor, Harvey, Glimcher, Laurie H

“…Antitumor responses depend on type 1 immunity, which is severely impaired in mice deficient for the T-box expressed in T cells (T-bet) transcription factor…”
Get full text

T-Bet-Dependent Expression of Osteopontin Contributes to T Cell Polarization by Shinohara, Mari L., Jansson, Marianne, Hwang, Eun Sook, Miriam B. F. Werneck, Glimcher, Laurie H., Cantor, Harvey

“…The osteopontin (Opn) glycoprotein has been implicated in diverse physiological processes, including vascularization, bone formation, and inflammatory…”
Get full text

The immunoregulatory effects of Qa-1 by Lu, Linrong, Werneck, Miriam B. F., Cantor, Harvey

“…The immune system is not only well equipped to control infections but also tightly controlled to prevent autoimmune disease. Despite the negative selection of…”
Get full text

NFAT1 transcription factor is central in the regulation of tissue microenvironment for tumor metastasis by Werneck, Miriam B. F., Vieira-de-Abreu, Adriana, Chammas, Roger, Viola, João P. B.

“…Members of the nuclear factor of activated T cell (NFAT) family of transcription factors were originally described in T lymphocytes but later shown to be…”
Get full text

Regulation of Activated CD4 + T Cells by NK Cells via the Qa-1–NKG2A Inhibitory Pathway by Lu, Linrong, Ikizawa, Koichi, Hu, Dan, Werneck, Miriam B.F., Wucherpfennig, Kai W., Cantor, Harvey

“…The ability of natural-killer cells to regulate adaptive immunity is not well understood. Here we define an interaction between the class Ib major…”
Get full text

Regulation of CD8⁺ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease by Lu, Linrong, Kim, Hye-Jung, Werneck, Miriam B.F, Cantor, Harvey

“…Regulation of autoreactive CD4 T cells is essential to maintain self-tolerance and prevent autoimmune disease. Although CD8 T regulatory (Treg) cells that…”
Get full text

Dual Roles for NFAT Transcription Factor Genes as Oncogenes and Tumor Suppressors by Robbs, Bruno K., Cruz, Andre L. S., Werneck, Miriam B. F., Mognol, Giuliana P., Viola, João P. B.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Differentiation of Memory CD8 T Cells Unravel Gene Expression Pattern Common to Effector and Memory Precursors by Neitzke-Montinelli, Vanessa, Calôba, Carolina, Melo, Guilherme, Frade, Bianca B, Caramez, Enzo, Mazzoccoli, Luciano, Gonçalves, André N A, Nakaya, Helder I, Pereira, Renata M, Werneck, Miriam B F, Viola, João P B

“…Long-term immunological protection relies on the differentiation and maintenance of memory lymphocytes. Since the knowledge of memory generation has been…”
Get full text

Cutting Edge: Polycomb Repressive Complex 1 Subunit Cbx4 Positively Regulates Effector Responses in CD8 T Cells by Melo, Guilherme A, Xu, Tianhao, Calôba, Carolina, Schutte, Alexander, Passos, Thaís O, Neto, Moisés A N, Brum, Gabrielle, Oliveira-Vieira, Bárbara, Higa, Luiza, Monteiro, Fábio L L, Berbert, Luiz, Gonçalves, André N A, Tanuri, Amilcar, Viola, João P B, Werneck, Miriam B F, Nakaya, Helder I, Pipkin, Matthew E, Martinez, Gustavo J, Pereira, Renata M

“…CTL differentiation is controlled by the crosstalk of various transcription factors and epigenetic modulators. Uncovering this process is fundamental to…”
Get full text

Osteopontin expression is essential for interferon-α production by plasmacytoid dendritic cells by Cantor, Harvey, Shinohara, Mari L, Lu, Linrong, Bu, Jing, Werneck, Miriam B F, Kobayashi, Koichi S, Glimcher, Laurie H

“…The observation that the T-bet transcription factor allows tissue-specific upregulation of intracellular osteopontin (Opn-i) in plasmacytoid dendritic cells…”
Get full text

TCR-dependent transformation of mature memory phenotype T cells in mice by Wang, Xi, Werneck, Miriam B F, Wilson, Boris G, Kim, Hye-Jung, Kluk, Michael J, Thom, Christopher S, Wischhusen, Jonathan W, Evans, Julia A, Jesneck, Jonathan L, Nguyen, Phuong, Sansam, Courtney G, Cantor, Harvey, Roberts, Charles W M

“…A fundamental goal in cancer research is the identification of the cell types and signaling pathways capable of initiating and sustaining tumor growth, as this…”
Get full text

Cyclosporin A inhibits colon cancer cell growth independently of the calcineurin pathway by Werneck, Miriam B.F., Hottz, Eugênio, Bozza, Patrícia T., Viola, João P.B.

“…Chronic inflammation is a risk factor for the development of colon cancer, providing genotoxic insults, growth and pro-angiogenic factors that can promote…”
Get full text

NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: evidence of its involvement in the control of cyclin gene expression by Caetano, Mauricio S., Vieira‐De‐Abreu, Adriana, Teixeira, Leonardo K., Werneck, Miriam B.F., Barcinski, Marcello A., Viola, João P.B.

“…ABSTRACT Upon antigen stimulation, lymphocytes enter in cell cycle and proliferate, and most of the activated T cells die by apoptosis. Many of the proteins…”
Get full text

Polycomb Repressive Complex 1 subunit Cbx4 positively regulates effector responses in CD8 T cells by Melo, Guilherme A., Xu, Tianhao, Calôba, Carolina, Schutte, Alexander, Passos, Thaís O., Neto, Moisés A. N., Brum, Gabrielle, Vieira, Bárbara M., Higa, Luiza, Monteiro, Fábio L. L., Berbet, Luiz, Gonçalves, André N.A., Tanuri, Amilcar, Viola, João P.B., Werneck, Miriam B. F., Nakaya, Helder I., Pipkin, Matthew E., Martinez, Gustavo J., Pereira, Renata M.

“…Cytotoxic T lymphocyte (CTL) differentiation is controlled by the crosstalk of various transcription factors and epigenetic modulators. Uncovering this process…”
Get full text

T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease1 by Werneck, Miriam B. F., Lugo-Villarino, Geanncarlo, Hwang, Eun Sook, Cantor, Harvey, Glimcher, Laurie H.

“…Antitumor responses depend on type 1 immunity, which is severely impaired in mice deficient for the T-box expressed in T cells (T-bet) transcription factor…”
Get full text

The immunoregulatory effects of Qa-1: Regulatory T Cells by LINRONG LU, WERNECK, Miriam B. F, CANTOR, Harvey

Get full text

Osteopontin expression is essential for interferon-[alpha] production by plasmacytoid dendritic cells by Shinohara, Mari L, Lu, Linrong, Bu, Jing, Werneck, Miriam B F, Kobayashi, Koichi S, Glimcher, Laurie H, Cantor, Harvey

“…The observation that the T-bet transcription factor allows tissue-specific upregulation of intracellular osteopontin (Opn-i) in plasmacytoid dendritic cells…”
Get full text

Regulation of CD8 super(+) regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease by Lu, Linrong, Kim, Hye-Jung, Werneck, Miriam BF, Cantor, Harvey

“…Regulation of autoreactive CD4 T cells is essential to maintain self-tolerance and prevent autoimmune disease. Although CD8 T regulatory (Treg) cells that…”
Get full text