Search Results - "Werhahn, J."

Impact of carbamazepine, lamotrigine, and levetiracetam on vascular risk markers and lipid‐lowering agents in the elderly by Mintzer, Scott, Trinka, Eugen, Kraemer, Günter, Chervoneva, Inna, Werhahn, Konrad J.

“…Summary Objective To examine serologic markers of vascular risk under treatment with commonly used antiepileptic drugs (AEDs) in the elderly in a randomized…”
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Efficacy, safety, and tolerability of lacosamide monotherapy versus controlled-release carbamazepine in patients with newly diagnosed epilepsy: a phase 3, randomised, double-blind, non-inferiority trial by Baulac, Michel, Prof, Rosenow, Felix, Prof, Toledo, Manuel, MD, Terada, Kiyohito, MD, Li, Ting, PhD, De Backer, Marc, MD, Werhahn, Konrad J, Prof, Brock, Melissa, PharmD

“…Summary Background Further options for monotherapy are needed to treat newly diagnosed epilepsy in adults. We assessed the efficacy, safety, and tolerability…”
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Feedbacks between air pollution and weather, part 2: Effects on chemistry by Makar, P.A., Gong, W., Hogrefe, C., Zhang, Y., Curci, G., Žabkar, R., Milbrandt, J., Im, U., Balzarini, A., Baró, R., Bianconi, R., Cheung, P., Forkel, R., Gravel, S., Hirtl, M., Honzak, L., Hou, A., Jiménez-Guerrero, P., Langer, M., Moran, M.D., Pabla, B., Pérez, J.L., Pirovano, G., San José, R., Tuccella, P., Werhahn, J., Zhang, J., Galmarini, S.

“…Fully-coupled air-quality models running in “feedback” and “no-feedback” configurations were compared against each other and observation network data as part…”
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Uncertainties of simulated aerosol optical properties induced by assumptions on aerosol physical and chemical properties: An AQMEII-2 perspective by Curci, G., Hogrefe, C., Bianconi, R., Im, U., Balzarini, A., Baró, R., Brunner, D., Forkel, R., Giordano, L., Hirtl, M., Honzak, L., Jiménez-Guerrero, P., Knote, C., Langer, M., Makar, P.A., Pirovano, G., Pérez, J.L., San José, R., Syrakov, D., Tuccella, P., Werhahn, J., Wolke, R., Žabkar, R., Zhang, J., Galmarini, S.

“…The calculation of aerosol optical properties from aerosol mass is a process subject to uncertainty related to necessary assumptions on the treatment of the…”
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Differential effects on motorcortical inhibition induced by blockade of GABA uptake in humans by Werhahn, Konrad J., Kunesch, Erwin, Noachtar, Soheyl, Benecke, Reiner, Classen, Joseph

“…Blockade of uptake carriers of γ-aminobutyric acid (GABA) has been shown to modulate inhibition in cortical slices of experimental animals, although little is…”
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The TERENO Pre‐Alpine Observatory: Integrating Meteorological, Hydrological, and Biogeochemical Measurements and Modeling by Kiese, R., Fersch, B., Baessler, C., Brosy, C., Butterbach-Bahl, K., Chwala, C., Dannenmann, M., Fu, J., Gasche, R., Grote, R., Jahn, C., Klatt, J., Kunstmann, H., Mauder, M., Rödiger, T., Smiatek, G., Soltani, M., Steinbrecher, R., Völksch, I., Werhahn, J., Wolf, B., Zeeman, M., Schmid, H.P.

“…Core Ideas Pre‐alpine areas face more intense warming and extreme hydrological events than the global average. Climate and land management change have…”
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Feedbacks between air pollution and weather, Part 1: Effects on weather by Makar, P.A., Gong, W., Milbrandt, J., Hogrefe, C., Zhang, Y., Curci, G., Žabkar, R., Im, U., Balzarini, A., Baró, R., Bianconi, R., Cheung, P., Forkel, R., Gravel, S., Hirtl, M., Honzak, L., Hou, A., Jiménez-Guerrero, P., Langer, M., Moran, M.D., Pabla, B., Pérez, J.L., Pirovano, G., San José, R., Tuccella, P., Werhahn, J., Zhang, J., Galmarini, S.

“…The meteorological predictions of fully coupled air-quality models running in “feedback” versus “no-feedback” simulations were compared against each other and…”
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Efficacy and safety of adjunctive padsevonil in adults with drug‐resistant focal epilepsy: Results from two double‐blind, randomized, placebo‐controlled trials by Rademacher, Michael, Toledo, Manuel, Van Paesschen, Wim, Liow, Kore K., Milanov, Ivan G., Esch, Maria‐Luise, Wang, Nan, MacPherson, Merran, Byrnes, William J., Minh, Timothy D. C., Webster, Elizabeth, Werhahn, Konrad J.

“…Objective To characterize efficacy, safety/tolerability, and pharmacokinetics of padsevonil (PSL) administered concomitantly with ≤3 antiseizure medications…”
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Latency of interictal epileptiform discharges in long-term EEG recordings in epilepsy patients by Werhahn, Konrad J, Hartl, Elisabeth, Hamann, Kristin, Breimhorst, Markus, Noachtar, Soheyl

“…Highlights • IED latency and frequency in EEG is not influenced by the presence of seizures. • IED latency correlates with epilepsy etiology, onset, and…”
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Reduced D2/D3 Receptor Binding of Extrastriatal and Striatal Regions in Temporal Lobe Epilepsy by Bernedo Paredes, Viviane E, Buchholz, Hans-Georg, Gartenschläger, Martin, Breimhorst, Markus, Schreckenberger, Mathias, Werhahn, Konrad J

“…Dopamine is an endogenous neuromodulator in cortical circuits and the basal ganglia. In animal models of temporal lobe epilepsy (TLE), seizure threshold is…”
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Contribution of the ipsilateral motor cortex to recovery after chronic stroke by Werhahn, Konrad J., Conforto, Adriana B., Kadom, Nadja, Hallett, Mark, Cohen, Leonardo G.

“…It has been proposed that the intact (ipsilateral) motor cortex play a significant role mediating recovery of motor function in the paretic hand of chronic…”
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Sensitivity of feedback effects in CBMZ/MOSAIC chemical mechanism by San José, R., Pérez, J.L., Balzarini, A., Baró, R., Curci, G., Forkel, R., Galmarini, S., Grell, G., Hirtl, M., Honzak, L., Im, U., Jiménez-Guerrero, P., Langer, M., Pirovano, G., Tuccella, P., Werhahn, J., Žabkar, R.

“…To investigate the impact of the aerosol effects on meteorological variables and pollutant concentrations two simulations with the WRF-Chem model have been…”
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Assessment of the MACC reanalysis and its influence as chemical boundary conditions for regional air quality modeling in AQMEII-2 by Giordano, L., Brunner, D., Flemming, J., Hogrefe, C., Im, U., Bianconi, R., Badia, A., Balzarini, A., Baró, R., Chemel, C., Curci, G., Forkel, R., Jiménez-Guerrero, P., Hirtl, M., Hodzic, A., Honzak, L., Jorba, O., Knote, C., Kuenen, J.J.P., Makar, P.A., Manders-Groot, A., Neal, L., Pérez, J.L., Pirovano, G., Pouliot, G., San José, R., Savage, N., Schröder, W., Sokhi, R.S., Syrakov, D., Torian, A., Tuccella, P., Werhahn, J., Wolke, R., Yahya, K., Žabkar, R., Zhang, Y., Galmarini, S.

“…The Air Quality Model Evaluation International Initiative (AQMEII) has now reached its second phase which is dedicated to the evaluation of online coupled…”
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Cortical excitability changes induced by deafferentation of the contralateral hemisphere by WERHAHN, Konrad J, MORTENSEN, Jennifer, KAELIN-LANG, Alain, BOROOJERDI, Babak, COHEN, Leonardo G

“…Short-term deprivation of sensory input by ischaemic nerve block (INB) leads to functional reorganization in the deafferented motor cortex. Here, we show that…”
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Functional connectivity between somatosensory and visual cortex in early blind humans by Wittenberg, George F., Werhahn, Konrad J., Wassermann, Eric M., Herscovitch, Peter, Cohen, Leonardo G.

“…Crossmodal plasticity occurs when loss of input in one sensory modality leads to reorganization in brain representations of other sensory modalities. In…”
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Enhanced tactile spatial acuity and cortical processing during acute hand deafferentation by Van Boven, Robert W, Cohen, Leonardo G, Werhahn, Konrad J, Mortensen, Jennifer, Zeuner, Kirsten E

“…Acute deafferentation of a limb results in bilateral cortical reorganization, but the behavioral consequences of this phenomenon are unknown. Here we found…”
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Evaluating the capability of regional-scale air quality models to capture the vertical distribution of pollutants by Solazzo, E, Bianconi, R, Pirovano, G, Moran, M. D, Vautard, R, Hogrefe, C, Appel, K. W, Matthias, V, Grossi, P, Bessagnet, B, Brandt, J, Chemel, C, Christensen, J. H, Forkel, R, Francis, X. V, Hansen, A. B, McKeen, S, Nopmongcol, U, Prank, M, Sartelet, K. N, Segers, A, Silver, J. D, Yarwood, G, Werhahn, J, Zhang, J, Rao, S. T, Galmarini, S

“…This study is conducted in the framework of the Air Quality Modelling Evaluation International Initiative (AQMEII) and aims at the operational evaluation of an…”
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Adjunctive brivaracetam in adults with uncontrolled focal epilepsy: Results from a double‐blind, randomized, placebo‐controlled trial by Ryvlin, Philippe, Werhahn, Konrad J., Blaszczyk, Barbara, Johnson, Martin E., Lu, Sarah

“…Summary Purpose Brivaracetam (BRV) is a novel high‐affinity synaptic vesicle protein 2A ligand in clinical development for the treatment of epilepsy. This…”
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Electroencephalography during functional echo-planar imaging: Detection of epileptic spikes using post-processing methods by Hoffmann, A., Jäger, L., Werhahn, K.J., Jaschke, M., Noachtar, S., Reiser, M.

“…EEG has been used to trigger functional MRI of patients with focal epilepsy, but EEG can be obscured by artifacts during MR data acquisition, and no continuous…”
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Early Diagnosis of Acanthamoeba Infection during Routine Cytological Examination of Cerebrospinal Fluid by Petry, Franz, Torzewski, Michael, Bohl, Jürgen, Wilhelm-Schwenkmezger, Thomas, Scheid, Patrick, Walochnik, Julia, Michel, Rolf, Zöller, Lothar, Werhahn, Konrad J, Bhakdi, Sucharit, Lackner, Karl J

“…Early identification of Acanthamoeba in cerebrospinal fluid is mandatory to prevent fatal granulomatous amebic encephalitis. In the case presented here amebic…”
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