Search Results - "Werginz, Paul"
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1
The impact of calcium current reversal on neurotransmitter release in the electrically stimulated retina
Published in Journal of neural engineering (01-08-2016)“…In spite of intense theoretical and experimental investigations on electrical nerve stimulation, the influence of reversed ion currents on network activity…”
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2
Scaling of the AIS and Somatodendritic Compartments in α S RGCs
Published in Frontiers in cellular neuroscience (27-09-2019)“…The anatomical properties of the axon initial segment (AIS) are tailored in certain types of CNS neurons to help optimize different aspects of neuronal…”
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3
Block Phenomena During Electric Micro-Stimulation of Pyramidal Cells and Retinal Ganglion Cells
Published in Frontiers in cellular neuroscience (26-11-2021)“…Electric micro-stimulation of the nervous system is a means to restore various body functions. The stimulus amplitude necessary to generate action potentials,…”
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4
Simulating auditory nerve fiber response following micro-electrode stimulation
Published in Current directions in biomedical engineering (01-12-2023)“…The cochlear implant was the first effective and is still the most common neuroprosthetic device which is employed for people with severe to profound hearing…”
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5
Avoidance of axonal activation in epiretinal implants using short biphasic pulses
Published in Current directions in biomedical engineering (06-09-2022)“…Retinal implants allow patients suffering from degenerative retinal diseases to regain visual percepts. Despite considerable effort in developing and improving…”
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Local field potentials of the auricular Vagus nerve - In-silico stimulation and recording
Published in Current directions in biomedical engineering (02-09-2022)Get full text
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7
Membrane depolarization mediates both the inhibition of neural activity and cell-type-differences in response to high-frequency stimulation
Published in Communications biology (18-06-2024)“…Neuromodulation using high frequency (>1 kHz) electric stimulation (HFS) enables preferential activation or inhibition of individual neural types, offering the…”
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8
Response of Mouse Visual Cortical Neurons to Electric Stimulation of the Retina
Published in Frontiers in neuroscience (04-04-2019)“…Retinal prostheses strive to restore vision to the blind by electrically stimulating the neurons that survive the disease process. Clinical effectiveness has…”
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9
Morphological Factors that Underlie Neural Sensitivity to Stimulation in the Retina
Published in Advanced NanoBiomed Research (Online) (01-12-2021)“…Retinal prostheses are a promising therapeutic intervention for patients afflicted by outer retinal degenerative diseases such as retinitis pigmentosa and…”
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10
Electric stimulus duration alters network-mediated responses depending on retinal ganglion cell type
Published in Journal of neural engineering (01-06-2018)“…To improve the quality of artificial vision that arises from retinal prostheses, it is important to bring electrically-elicited neural activity more in line…”
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11
A finite element method framework to model extracellular neural stimulation
Published in Journal of neural engineering (01-04-2022)“…Increasing complexity in extracellular stimulation experiments and neural implant design also requires realistic computer simulations capable of modeling the…”
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12
The relationship between morphological properties and thresholds to extracellular electric stimulation in α RGCs
Published in Journal of neural engineering (27-08-2020)“…Retinal prostheses strive to restore vison to patients that are blind from retinal degeneration by electrically stimulating surviving retinal ganglion cells…”
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Journal Article -
13
On optimal coupling of the 'electronic photoreceptors' into the degenerate retina
Published in Journal of neural engineering (01-08-2020)“…To restore sight in atrophic age-related macular degeneration, the lost photoreceptors can be replaced with electronic implants, which replicate their two…”
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14
Avoidance of axonal stimulation with sinusoidal epiretinal stimulation
Published in Journal of neural engineering (01-04-2024)“…Neuromodulation, particularly electrical stimulation, necessitates high spatial resolution to achieve artificial vision with high acuity. In epiretinal…”
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15
Simulating auditory nerve fiber response following micro-electrode stimulation: Comparing efficiency of electrode placements in the scala tympani and scala vestibuli
Published in Current directions in biomedical engineering (01-12-2023)“…Abstract The cochlear implant was the first effective and is still the most common neuroprosthetic device which is employed for people with severe to profound…”
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Journal Article -
16
Morphological Factors that Underlie Neural Sensitivity to Stimulation in the Retina
Published in Advanced NanoBiomed Research (Online) (01-12-2021)“…Retinal Degenerative Diseases Recent advances in retinal protheses offer new opportunities to restore sight in patients with vision loss. Shown here is a…”
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17
Identification of Axon Bendings in Neurons by Multiphysics FEM Simulations of High-Density MEA Extracellular Recordings
Published in 2023 IEEE SENSORS (29-10-2023)“…A three-dimensional finite element method (FEM) simulation of a neuron (retinal ganglion cell) interfaced to a high-density CMOS-based microelectrode array…”
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Conference Proceeding -
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Tailoring of the axon initial segment shapes the conversion of synaptic inputs into spiking output in OFF-α T retinal ganglion cells
Published in Science advances (01-09-2020)“…Recently, mouse OFF-α transient (OFF-α T) retinal ganglion cells (RGCs) were shown to display a gradient of light responses as a function of position along the…”
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Simulation Of The Electrical Field Generated By Bipolar And Ganglion Cells In The Electrically Stimulated Retina
Published in Frontiers in neuroscience (2016)“…Abstract only…”
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20
Variability in Depolarization Sensitivity Underlies Differential Responses to High-frequency Stimulation of ON and OFF RGCs
Published in 2023 11th International IEEE/EMBS Conference on Neural Engineering (NER) (24-04-2023)“…Retinal prostheses aim to restore vision to patients with outer retinal degeneration, but the quality of restored vision is still far below that of the healthy…”
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Conference Proceeding