Search Results - "Werff‐ten Bosch, Jutte"

Deciphering the Non-Coding RNA Landscape of Pediatric Acute Myeloid Leukemia by Vanhooren, Jolien, Van Camp, Laurens, Depreter, Barbara, de Jong, Martijn, Uyttebroeck, Anne, Van Damme, An, Dedeken, Laurence, Dresse, Marie-Françoise, van der Werff Ten Bosch, Jutte, Hofmans, Mattias, Philippé, Jan, De Moerloose, Barbara, Lammens, Tim

“…Pediatric acute myeloid leukemia (pedAML) is a heterogeneous blood cancer that affects children. Although survival rates have significantly improved over the…”
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Response‐guided chemotherapy for pediatric acute myeloid leukemia without hematopoietic stem cell transplantation in first complete remission: Results from protocol DB AML‐01 by Moerloose, Barbara, Reedijk, Ardine, Bock, Geertruida H, Lammens, Tim, Haas, Valerie, Denys, Barbara, Dedeken, Laurence, den Heuvel‐Eibrink, Marry M., te Loo, Maroeska, Uyttebroeck, Anne, Damme, An, der Werff‐ten Bosch, Jutte, Zsiros, Jozsef, Kaspers, Gertjan, Bont, Eveline

“…Background Children with acute myeloid leukemia (AML) have a 70% survival rate with treatment regimens containing high doses of cytarabine and anthracyclines…”
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Gonadal development and function after immature testicular tissue banking as part of high‐risk gonadotoxic treatment by Braye, Aude, Delgouffe, Emily, Werff ten Bosch, Jutte, Gies, Inge, Ferster, Alina, Goossens, Ellen

“…Background Experimental fertility preservation programs have been started to safeguard the future fertility of prepubertal and pubertal males requiring…”
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Randomized controlled trial on the effect of 1‐hour infusion of vincristine versus push injection on neuropathy in children with cancer (final analysis) by Uittenboogaard, Aniek, Berg, Marleen H., Abbink, Floor C. H., Twisk, Jos W. R., Sluis, Inge M., Bos, Cor, Heuvel‐Eibrink, Marry M., Segers, Heidi, Chantrain, Christophe, Werff ten Bosch, Jutte, Willems, Leen, Kaspers, Gertjan J. L., Velde, Mirjam Esther

“…IntroductionVincristine is an integral component of treatment for children with cancer. Its main dose‐limiting side effect is vincristine‐induced peripheral…”
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Homozygous NLRP1 gain-of-function mutation in siblings with a syndromic form of recurrent respiratory papillomatosis by Drutman, Scott B., Haerynck, Filomeen, Zhong, Franklin L., Hum, David, Hernandez, Nicholas J., Belkaya, Serkan, Rapaport, Franck, de Jong, Sarah Jill, Creytens, David, Tavernier, Simon J., Bonte, Katrien, De Schepper, Sofie, van der Werff ten Bosch, Jutte, Lorenzo-Diaz, Lazaro, Wullaert, Andy, Bossuyt, Xavier, Orth, Gérard, Bonagura, Vincent R., Béziat, Vivien, Abel, Laurent, Jouanguy, Emmanuelle, Reversade, Bruno, Casanova, Jean-Laurent

“…Juvenile-onset recurrent respiratory papillomatosis (JRRP) is a rare and debilitating childhood disease that presents with recurrent growth of papillomas in…”
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Results of successive EORTC‐CLG 58 881 and 58 951 trials in paediatric T‐cell acute lymphoblastic leukaemia (ALL) by Hofmans, Mattias, Suciu, Stefan, Ferster, Alina, Van Vlierberghe, Pieter, Mazingue, Françoise, Sirvent, Nicolas, Costa, Vitor, Yakouben, Karima, Paillard, Catherine, Uyttebroeck, Anne, Plantaz, Dominique, Plat, Geneviève, Simon, Pauline, Millot, Frédéric, Poirée, Marilyne, van der Werff ten Bosch, Jutte, Piette, Caroline, Minckes, Odile, Rohrlich, Pierre, Girard, Sandrine, Cavé, Hélène, Bertrand, Yves, De Moerloose, Barbara

“…Summary Outcomes in childhood T‐cell acute lymphoblastic leukaemia (T‐ALL) are steadily improving due to intensive therapy. Between 1989 and 2008, 599 children…”
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Clinical characteristics of patients with low functional IL-6 production upon TLR/IL-1R stimulation by Frans, Glynis, MPharm, PhD, Van der Werff Ten Bosch, Jutte, MD, PhD, Moens, Leen, PhD, Wuyts, Greet, BSc, Schaballie, Heidi, MD, Tuerlinckx, David, MD, De Bie, Mia, MD, Vermeulen, Francois, MD, Schrijvers, Rik, MD, PhD, Meert, Wim, MSc, Hestand, Matthew S., PhD, Delanghe, Joris, MD, PhD, Vermeesch, Joris R., PhD, Meyts, Isabelle, MD, PhD, Bossuyt, Xavier, MD, PhD

“…Low IL-6 production upon stimulation by TLR/IL-1R ligands is associated with increased susceptibility to bacterial skin infections and to invasive infections…”
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Population Pharmacokinetics of Vincristine Related to Infusion Duration and Peripheral Neuropathy in Pediatric Oncology Patients by van de Velde, Mirjam Esther, Panetta, John Carl, Wilhelm, Abraham J., van den Berg, Marleen H., van der Sluis, Inge M., van den Bos, Cor, Abbink, Floor C.H., van den Heuvel-Eibrink, Marry M., Segers, Heidi, Chantrain, Christophe, van der Werff Ten Bosch, Jutte, Willems, Leen, Evans, William E., Kaspers, Gertjan L.

“…Vincristine (VCR) is frequently used in pediatric oncology and can be administered intravenously through push injections or 1 h infusions. The effects of…”
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Prospective, real‐time monitoring of pegylated Escherichia coli and Erwinia asparaginase therapy in childhood acute lymphoblastic leukaemia and non‐Hodgkin lymphoma in Belgium by Mondelaers, Veerle, Ferster, Alina, Uyttebroeck, Anne, Brichard, Bénédicte, Werff ten Bosch, Jutte, Norga, Koenraad, Francotte, Nadine, Piette, Caroline, Vandemeulebroecke, Katrien, Verbeke, Charlotte, Schmidt, Susanne, Benoit, Yves, Lammens, Tim, De Moerloose, Barbara

“…Summary Asparaginase (ASNase) is an important anti‐leukaemic drug in the treatment of childhood acute lymphoblastic leukaemia (ALL) and non‐Hodgkin lymphoma…”
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Ribosomal protein gene RPL9 variants can differentially impair ribosome function and cellular metabolism by Lezzerini, Marco, Penzo, Marianna, O’Donohue, Marie-Françoise, Marques dos Santos Vieira, Carolina, Saby, Manon, Elfrink, Hyung L, Diets, Illja J, Hesse, Anne-Marie, Couté, Yohann, Gastou, Marc, Nin-Velez, Alexandra, Nikkels, Peter G J, Olson, Alexandra N, Zonneveld-Huijssoon, Evelien, Jongmans, Marjolijn C J, Zhang, GuangJun, van Weeghel, Michel, Houtkooper, Riekelt H, Wlodarski, Marcin W, Kuiper, Roland P, Bierings, Marc B, van der Werff ten Bosch, Jutte, Leblanc, Thierry, Montanaro, Lorenzo, Dinman, Jonathan D, Da Costa, Lydie, Gleizes, Pierre-Emmanuel, MacInnes, Alyson W

“…Abstract Variants in ribosomal protein (RP) genes drive Diamond-Blackfan anemia (DBA), a bone marrow failure syndrome that can also predispose individuals to…”
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Healthcare interventions improving and reducing quality of life in children at the end of life: a systematic review by Piette, Veerle, Beernaert, Kim, Cohen, Joachim, Pauwels, Nele S., Scherrens, Anne-lore, van der Werff ten Bosch, Jutte, Deliens, Luc

“…Background Children with serious illness suffer from symptoms at the end of life that often fail to be relieved. An overview is required of healthcare…”
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Deciphering molecular heterogeneity in pediatric AML using a cancer vs. normal transcriptomic approach by Depreter, Barbara, De Moerloose, Barbara, Vandepoele, Karl, Uyttebroeck, Anne, Van Damme, An, Terras, Eva, Denys, Barbara, Dedeken, Laurence, Dresse, Marie-Françoise, Van der Werff Ten Bosch, Jutte, Hofmans, Mattias, Philippé, Jan, Lammens, Tim

“…Background Still 30–40% of pediatric acute myeloid leukemia (pedAML) patients relapse. Delineation of the transcriptomic profile of leukemic subpopulations…”
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A Congenital Neutrophil Defect Syndrome Associated with Mutations in VPS45 by Vilboux, Thierry, Lev, Atar, Malicdan, May Christine V, Simon, Amos J, Järvinen, Päivi, Racek, Tomas, Puchalka, Jacek, Sood, Raman, Carrington, Blake, Bishop, Kevin, Mullikin, James, Huizing, Marjan, Garty, Ben Zion, Eyal, Eran, Wolach, Baruch, Gavrieli, Ronit, Toren, Amos, Soudack, Michalle, Atawneh, Osama M, Babushkin, Tatiana, Schiby, Ginette, Cullinane, Andrew, Avivi, Camila, Polak-Charcon, Sylvie, Barshack, Iris, Amariglio, Ninette, Rechavi, Gideon, van der Werff ten Bosch, Jutte, Anikster, Yair, Klein, Christoph, Gahl, William A, Somech, Raz

“…Seven children in five families were found to have homozygous mutations in a gene associated with vacuolar protein sorting, VPS45, which regulates endosomal…”
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Risk of malignancy in 22q11.2 deletion syndrome by Stevens, Toer, Werff ten Bosch, Jutte, De Rademaeker, Marjan, Van Den Bogaert, Ann, Akker, Machiel

“…Key Clinical Message 22q11.2DS is a significant health problem because of its fairly high incidence. It is relevant to be vigilant regarding the diagnosis of…”
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Vincristine-Induced Peripheral Neuropathy in Pediatric Oncology: A Randomized Controlled Trial Comparing Push Injections with One-Hour Infusions (The VINCA Trial) by van de Velde, Mirjam Esther, Kaspers, Gertjan J L, Abbink, Floor C H, Twisk, Jos W R, van der Sluis, Inge M, van den Bos, Cor, van den Heuvel-Eibrink, Marry M, Segers, Heidi, Chantrain, Christophe, van der Werff Ten Bosch, Jutte, Willems, Leen, van den Berg, Marleen H

“…Vincristine (VCR) is a frequently used chemotherapeutic agent. However, it can lead to VCR-induced peripheral neuropathy (VIPN). In this study we investigated…”
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Long‐term outcome evaluation of medium/high risk acute lymphoblastic leukaemia children treated with or without cranial radiotherapy in the EORTC 58832 randomized study by Piette, Caroline, Suciu, Stefan, Bertrand, Yves, Uyttebroeck, Anne, Vandecruys, Els, Plat, Geneviève, Paillard, Catherine, Pluchart, Claire, Sirvent, Nicolas, Maurus, Renée, Poirée, Maryline, Simon, Pauline, Ferster, Alina, Hoyoux, Claire, Mazingue, Françoise, Paulus, Robert, Freycon, Claire, Thomas, Caroline, Philippet, Pierre, Gilotay, Caroline, Werff Ten Bosch, Jutte, Rohrlich, Pierre S., Benoit, Yves

“…Summary We investigated the long‐term outcome, the incidence of second neoplasms (SN) and the rate of late adverse effects (LAE) in children with central…”
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Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis by Matlung, Hanke L., Babes, Liane, Zhao, Xi Wen, van Houdt, Michel, Treffers, Louise W., van Rees, Dieke J., Franke, Katka, Schornagel, Karin, Verkuijlen, Paul, Janssen, Hans, Halonen, Pasi, Lieftink, Cor, Beijersbergen, Roderick L., Leusen, Jeanette H.W., Boelens, Jaap J., Kuhnle, Ingrid, van der Werff Ten Bosch, Jutte, Seeger, Karl, Rutella, Sergio, Pagliara, Daria, Matozaki, Takashi, Suzuki, Eiji, Menke-van der Houven van Oordt, Catharina Willemien, van Bruggen, Robin, Roos, Dirk, van Lier, Rene A.W., Kuijpers, Taco W., Kubes, Paul, van den Berg, Timo K.

“…Destruction of cancer cells by therapeutic antibodies occurs, at least in part, through antibody-dependent cellular cytotoxicity (ADCC), and this can be…”
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Attending school after treatment for a brain tumor: Experiences of children and key figures by Vanclooster, Stephanie, Bilsen, Johan, Peremans, Lieve, Van der Werff Ten Bosch, Jutte, Laureys, Geneviève, Willems, Elsie, Genin, Sophie, Van Bogaert, Patrick, Paquier, Philippe, Jansen, Anna

“…Reintegration into school is a milestone for childhood brain tumor survivors, as well as for their parents, teachers, and healthcare providers. We explored…”
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Pain science education for children living with and beyond cancer: Challenges and research agenda by Rheel, Emma, Heathcote, Lauren C., van der Werff ten Bosch, Jutte, Schulte, Fiona, Pate, Joshua W.

“…Pain in children living with and beyond cancer is understudied and undertreated. Pain science education (PSE) is a conceptual change strategy facilitating…”
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JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia by Boztug, Kaan, Järvinen, Päivi M, Salzer, Elisabeth, Racek, Tomas, Mönch, Sebastian, Garncarz, Wojciech, Gertz, E Michael, Schäffer, Alejandro A, Antonopoulos, Aristotelis, Haslam, Stuart M, Schieck, Lena, Puchałka, Jacek, Diestelhorst, Jana, Appaswamy, Giridharan, Lescoeur, Brigitte, Giambruno, Roberto, Bigenzahn, Johannes W, Elling, Ulrich, Pfeifer, Dietmar, Conde, Cecilia Domínguez, Albert, Michael H, Welte, Karl, Brandes, Gudrun, Sherkat, Roya, van der Werff ten Bosch, Jutte, Rezaei, Nima, Etzioni, Amos, Bellanné-Chantelot, Christine, Superti-Furga, Giulio, Penninger, Josef M, Bennett, Keiryn L, von Blume, Julia, Dell, Anne, Donadieu, Jean, Klein, Christoph

“…Christoph Klein and colleagues identify homozygous mutations in the JAGN1 gene in families and individuals with severe congenital neutropenia. They show that…”
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