Search Results - "Wepy, James A."

Methylglyoxal-derived posttranslational arginine modifications are abundant histone marks by Galligan, James J., Wepy, James A., Streeter, Matthew D., Kingsley, Philip J., Mitchener, Michelle M., Wauchope, Orrette R., Beavers, William N., Rose, Kristie L., Wang, Tina, Spiegel, David A., Marnett, Lawrence J.

“…Histone posttranslational modifications (PTMs) regulate chromatin dynamics, DNA accessibility, and transcription to expand the genetic code. Many of these PTMs…”
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Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling[S] by Wepy, James A., Galligan, James J., Kingsley, Philip J., Xu, Shu, Goodman, Michael C., Tallman, Keri A., Rouzer, Carol A., Marnett, Lawrence J.

“…Lysophospholipids (LysoPLs) are bioactive lipid species involved in cellular signaling processes and the regulation of cell membrane structure. LysoPLs are…”
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Erratum: Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling by Wepy, James A., Galligan, James J., Kingsley, Phillip J., Xu, Shu, Goodman, Michael C., Tallman, Keri A., Rouzer, Carol A., Marnett, Lawrence J.

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Identification of the Major Prostaglandin Glycerol Ester Hydrolase in Human Cancer Cells by Manna, Joseph D., Wepy, James A., Hsu, Ku-Lung, Chang, Jae Won, Cravatt, Benjamin F., Marnett, Lawrence J.

“…Prostaglandin glycerol esters (PG-Gs) are produced as a result of the oxygenation of the endocannabinoid, 2-arachidonoylglycerol, by cyclooxygenase 2…”
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Quantitative Analysis and Discovery of Lysine and Arginine Modifications by Galligan, James J, Kingsley, Philip J, Wauchope, Orrette R, Mitchener, Michelle M, Camarillo, Jeannie M, Wepy, James A, Harris, Peter S, Fritz, Kristofer S, Marnett, Lawrence J

“…Post-translational modifications (PTMs) affect protein function, localization, and stability, yet very little is known about the ratios of these modifications…”
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Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D4 Receptor with in Vivo Activity by Berry, Cynthia B, Bubser, Michael, Jones, Carrie K, Hayes, John P, Wepy, James A, Locuson, Charles W, Daniels, J. Scott, Lindsley, Craig W, Hopkins, Corey R

“…Herein, we report the structure–activity relationship of a chiral morpholine-based scaffold, which led to the identification of a potent and selective dopamine…”
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Discovery and Characterization of ML398, a Potent and Selective Antagonist of the D 4 Receptor with in Vivo Activity by Berry, Cynthia B., Bubser, Michael, Jones, Carrie K., Hayes, John P., Wepy, James A., Locuson, Charles W., Daniels, J. Scott, Lindsley, Craig W., Hopkins, Corey R.

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