Search Results - "Wenzel, Pamela L"

Fluid shear stress activates YAP1 to promote cancer cell motility by Lee, Hyun Jung, Diaz, Miguel F., Price, Katherine M., Ozuna, Joyce A., Zhang, Songlin, Sevick-Muraca, Eva M., Hagan, John P., Wenzel, Pamela L.

“…Mechanical stress is pervasive in egress routes of malignancy, yet the intrinsic effects of force on tumour cells remain poorly understood. Here, we…”
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Mitochondrial Transfer and Regulators of Mesenchymal Stromal Cell Function and Therapeutic Efficacy by Mohammadalipour, Amina, Dumbali, Sandeep P, Wenzel, Pamela L

“…Mesenchymal stromal cell (MSC) metabolism plays a crucial role in the surrounding microenvironment in both normal physiology and pathological conditions. While…”
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Editorial: Advances and methods in mesenchymal stem cells by Wenzel, Pamela L

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AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate by Gu, Qilin, Yang, Xiaojie, Lv, Jie, Zhang, Jiaxiong, Xia, Bo, Kim, Jun-Dae, Wang, Ruoyu, Xiong, Feng, Meng, Shu, Clements, Thomas P, Tandon, Bhavna, Wagner, Daniel S, Diaz, Miguel F, Wenzel, Pamela L, Miller, Yury I, Traver, David, Cooke, John P, Li, Wenbo, Zon, Leonard I, Chen, Kaifu, Bai, Yongping, Fang, Longhou

“…Hypercholesterolemia, the driving force of atherosclerosis, accelerates the expansion and mobilization of hematopoietic stem and progenitor cells (HSPCs). The…”
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Prostaglandin E2 Indicates Therapeutic Efficacy of Mesenchymal Stem Cells in Experimental Traumatic Brain Injury by Kota, Daniel J., Prabhakara, Karthik S., Toledano‐Furman, Naama, Bhattarai, Deepa, Chen, Qingzheng, DiCarlo, Bryan, Smith, Philippa, Triolo, Fabio, Wenzel, Pamela L., Cox, Charles S., Olson, Scott D.

“…Traumatic brain injury (TBI) is soon predicted to become the third leading cause of death and disability worldwide. After the primary injury, a complex set of…”
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Ex Vivo Modeling of Hematopoietic Stem Cell Homing to the Fetal Liver by Mohammadalipour, Amina, Diaz, Miguel F, Pareek, Sumedha, Wenzel, Pamela L

“…Hematopoietic stem cells (HSCs) are used in the clinic to provide life-saving therapies to patients with a variety of hematological malignancies and disorders…”
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Effect of Developmental Stage of HSC and Recipient on Transplant Outcomes by Arora, Natasha, Wenzel, Pamela L., McKinney-Freeman, Shannon L., Ross, Samantha J., Kim, Peter G., Chou, Stephanie S., Yoshimoto, Momoko, Yoder, Mervin C., Daley, George Q.

“…The first hematopoietic stem cells (HSCs) that engraft irradiated adult mice arise in the aorta-gonad-mesonephros (AGM) on embryonic day 11.5 (E11.5). However,…”
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Biomechanical forces promote blood development through prostaglandin E2 and the cAMP-PKA signaling axis by Diaz, Miguel F, Li, Nan, Lee, Hyun Jung, Adamo, Luigi, Evans, Siobahn M, Willey, Hannah E, Arora, Natasha, Torisawa, Yu-Suke, Vickers, Dwayne A, Morris, Samantha A, Naveiras, Olaia, Murthy, Shashi K, Ingber, Donald E, Daley, George Q, García-Cardeña, Guillermo, Wenzel, Pamela L

“…Blood flow promotes emergence of definitive hematopoietic stem cells (HSCs) in the developing embryo, yet the signals generated by hemodynamic forces that…”
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E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells by Chong, Jean-Leon, Wang, Shu-Huei, Ouseph, Madhu, Leone, Gustavo, Pipas, James M, Robinson, Michael L, Wenzel, Pamela L, Cantalupo, Paul G, Sharma, Nidhi, Culp, Brian, Sáenz-Robles, M. Teresa, Nair, Vivek, Mezache, Louise, Winton, Douglas J, Hagan, John P, Sansom, Owen J, Chen, Danian, Ferrey, Antoney, Chen, Hui-Zi, Bremner, Rod, Trikha, Prashant, Gomez, Yorman M

“…In the established model of mammalian cell cycle control, the retinoblastoma protein (Rb) functions to restrict cells from entering S phase by binding and…”
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Bone marrow stromal cell therapy improves survival after radiation injury but does not restore endogenous hematopoiesis by Diaz, Miguel F., Horton, Paulina D., Dumbali, Sandeep P., Kumar, Akshita, Livingston, Megan, Skibber, Max A., Mohammadalipour, Amina, Gill, Brijesh S., Zhang, Songlin, Cox, Charles S., Wenzel, Pamela L.

“…The only available option to treat radiation-induced hematopoietic syndrome is allogeneic hematopoietic cell transplantation, a therapy unavailable to many…”
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Mitochondrial permeability transition dictates mitochondrial maturation upon switch in cellular identity of hematopoietic precursors by Dumbali, Sandeep P., Horton, Paulina D., Moore, Travis I., Wenzel, Pamela L.

“…The mitochondrial permeability transition pore (mPTP) is a supramolecular channel that regulates exchange of solutes across cristae membranes, with executive…”
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Publisher Correction: Bone marrow stromal cell therapy improves survival after radiation injury but does not restore endogenous hematopoiesis by Diaz, Miguel F., Horton, Paulina D., Dumbali, Sandeep P., Kumar, Akshita, Livingston, Megan, Skibber, Max A., Mohammadalipour, Amina, Gill, Brijesh S., Zhang, Songlin, Cox, Charles S., Wenzel, Pamela L.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium by Jang, Il Ho, Lu, Yi-Fen, Zhao, Long, Wenzel, Pamela L., Kume, Tsutomu, Datta, Sumon M., Arora, Natasha, Guiu, Jordi, Lagha, Mounia, Kim, Peter G., Do, Eun Kyoung, Kim, Jae Ho, Schlaeger, Thorsten M., Zon, Leonard I., Bigas, Anna, Burns, Caroline E., Daley, George Q.

“…Hematopoietic and vascular development share many common features, including cell surface markers and sites of origin. Recent lineage-tracing studies have…”
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Mechanoregulation in Hematopoiesis and Hematologic Disorders by Horton, Paulina D., Dumbali, Sandeep, Wenzel, Pamela L.

“…Purpose of Review Hematopoietic stem cells (HSCs) are reliant on intrinsic and extrinsic factors for tight control of self-renewal, quiescence,…”
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Persistent tailoring of MSC activation through genetic priming by Beauregard, Michael A., Bedford, Guy C., Brenner, Daniel A., Sanchez Solis, Leonardo D., Nishiguchi, Tomoki, Abhimanyu, Longlax, Santiago Carrero, Mahata, Barun, Veiseh, Omid, Wenzel, Pamela L., DiNardo, Andrew R., Hilton, Isaac B., Diehl, Michael R.

“…Mesenchymal stem/stromal cells (MSCs) are an attractive platform for cell therapy due to their safety profile and unique ability to secrete broad arrays of…”
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Expression of Cre recombinase in early diploid trophoblast cells of the mouse placenta by Wenzel, Pamela L., Leone, Gustavo

“…An increasing number of genes known to be critical for cell cycle control, differentiation, and tumor suppression have been found to impact development of the…”
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RhoA‐ROCK competes with YAP to regulate amoeboid breast cancer cell migration in response to lymphatic‐like flow by Mohammadalipour, Amina, Diaz, Miguel F., Livingston, Megan, Ewere, Adesuwa, Zhou, Allen, Horton, Paulina D., Olamigoke, Loretta T., Lamar, John M., Hagan, John P., Lee, Hyun J., Wenzel, Pamela L.

“…Lymphatic drainage generates force that induces prostate cancer cell motility via activation of Yes‐associated protein (YAP), but whether this response to…”
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Cell proliferation in the absence of E2F1-3 by Wenzel, Pamela L., Chong, Jean-Leon, Sáenz-Robles, M. Teresa, Ferrey, Antoney, Hagan, John P., Gomez, Yorman M., Rajmohan, Ravi, Sharma, Nidhi, Chen, Hui-Zi, Pipas, James M., Robinson, Michael L., Leone, Gustavo

“…E2F transcription factors regulate the progression of the cell cycle by repression or transactivation of genes that encode cyclins, cyclin dependent kinases,…”
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Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment by Daley, George Q, Naveiras, Olaia, Nardi, Valentina, Wenzel, Pamela L, Hauschka, Peter V, Fahey, Frederic

“…Osteoblasts and endothelium constitute functional niches that support haematopoietic stem cells in mammalian bone marrow. Adult bone marrow also contains…”
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Rb is critical in a mammalian tissue stem cell population by Wenzel, Pamela L, Wu, Lizhao, de Bruin, Alain, Chong, Jean-Leon, Chen, Wen-Yi, Dureska, Geoffrey, Sites, Emily, Pan, Tony, Sharma, Ashish, Huang, Kun, Ridgway, Randall, Mosaliganti, Kishore, Sharp, Richard, Machiraju, Raghu, Saltz, Joel, Yamamoto, Hideyuki, Cross, James C, Robinson, Michael L, Leone, Gustavo

“…The inactivation of the retinoblastoma (Rb) tumor suppressor gene in mice results in ectopic proliferation, apoptosis, and impaired differentiation in…”
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